Tetramethylpyrazine downregulates angiotensin II-induced endothelin-1 gene expression in vascular endothelial cells

Clinical and Experimental Pharmacology and Physiology

Volumn 32, Issue 10, 2005, Pages 845-850

  Lee, Wen Sen ^a   Yang, Hung Yu ^a   Kao, Pai Feng ^a   Liu, Ju Chi ^a   Chen, Cheng Hsien ^a   Cheng, Tzu Hurng ^a   Chan, Paul ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Angiotensin II; Endothelial cells; Endothelin 1; Extracellular signal regulated kinase; Reactive oxygen species; Tetramethylpyrazine

Indexed keywords

ANGIOTENSIN II; ENDOTHELIN 1; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; TETRAMETHYLPYRAZINE; ANTIOXIDANT; CHLORAMPHENICOL ACETYLTRANSFERASE; HYBRID PROTEIN; MESSENGER RNA; PYRAZINE DERIVATIVE; SUPEROXIDE;

ARTICLE; CARDIOVASCULAR SYSTEM; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INCUBATION TIME; NORTHERN BLOTTING; OXIDATION REDUCTION REACTION; PROMOTER REGION; SENSITIVITY ANALYSIS; VASCULAR ENDOTHELIUM; CYTOLOGY; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; PHOSPHORYLATION; WESTERN BLOTTING;

ANGIOTENSIN II; ANTIOXIDANTS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DOWN-REGULATION; ENDOTHELIAL CELLS; ENDOTHELIN-1; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HUMANS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PYRAZINES; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SUPEROXIDES; TRANSFECTION;

EID: 33644685199     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2005.04275.x     Document Type: Article

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