Engineered bone from bone marrow stromal cells: A structural study by an advanced x-ray microdiffraction technique

Physics in Medicine and Biology

Volumn 51, Issue 6, 2006, Pages

  Cedola, A ^a,b   Mastrogiacomo, M ^c   Burghammer, M ^d   Komlev, V ^b,e   Giannoni, P ^f   Favia, A ^g   Cancedda, R ^c   Rustichelli, F ^b   Lagomarsino, S ^a,b  

^a IFN CNR   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^e RUSSIAN ACADEMY OF SCIENCES   (Russian Federation)

^f Biorigen Srl   (Italy)

^g UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; BONE; CELLS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; X RAY DIFFRACTION;

BONE CRYSTALS; MICRODIFFRACTION; TISSUE ENGINEERING;

RADIOGRAPHY;

BIOMATERIAL; COLLAGEN; COLLAGEN FIBRIL;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE TISSUE; CERAMICS; CONTROLLED STUDY; FIBER; MOUSE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STROMA CELL; TISSUE ENGINEERING; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANISOTROPY; BIOCOMPATIBLE MATERIALS; BONE AND BONES; BONE DENSITY; BONE MARROW CELLS; CERAMICS; COLLAGEN; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; SCATTERING, RADIATION; STROMAL CELLS; SYNCHROTRONS; TISSUE ENGINEERING; TOLONIUM CHLORIDE; X-RAY DIFFRACTION; X-RAYS;

EID: 33644681564     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/51/6/N02     Document Type: Article

References (22)

1. Camacho N P, Rinnerthaler S, Paschalis E P, Mendelsohn R, Boskey A L and Fratzl P 1999 Complementary information on bone ultrastructure from scanning small angle scattering and Fourier-transform infrared microspectroscopy Bone 25 287-93
2. Cameron G J, Alberts I L, Laing J H and Wess T J 2002 Structure of type I and type III heterotypic collagen fibrils: an X-ray diffraction study J. Struct. Biol. 137 15-22
3. Dalconi M C, Meneghini C, Nuzzo S, Wenk R H and Mobilio S 2003 Structure of bioapatite in human foetal bones: an x-ray microdiffraction study Nucl. Instrum. Methods Phys. Res. 200 406
4. EEC 1987 EEC Council Directive 86/609, OJL 358, December 12th 1987
5. Fratzl P, Fratzl-Zelman N, Klaushofer K, Vogl G and Koller K 1991 Nucleation and growth of mineral crystals in bone studied by small-angle X-ray scattering Calcif. Tissue Int. 48 407
6. Giacovazzo C, Monaco H, Artioli G, Viterbo D, Ferraris G and Gilli G 2002 Fundamentals of Crystallography 2nd edn (Oxford: OUP)
7. Guide for the Care and Use of Laboratory Animals 1996 US Natl. Res. Council and www.bvet.admin.ch
8. Jark W, Di Fonzo S, Lagomarsino S, Cedola A, Di Fabrizio E, Bram A and Riekel C 1996 Properties of a submicrometer x-ray beam at the exit of a waveguide J. Appl. Phys. 80 4831
9. Jark W, Cedola A, Di Fonzo S, Fiordelisi M, Lagomarsino S, Kovalenko N V and Chernov V A 2001 A new generation x-ray microscpy and nanodiffraction Appl. Phys. Lett. 78 1192
10. Kon E, Muraglia A, Corsi A, Bianco P, Marcacci M, Martin I, Boyde A, Ruspantini I, Chistolini P, Rocca M, Giardino R, Cancedda R and Quarto R 2000 Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones J. Biomed. Mater. Res. 49 328
11. Lagomarsino S, Jark W, Di Fonzo S, Cedola A, Mueller B, Engstrom P and Riekel C 1996 Sub-micro-meter X-ray beam production by a thin film waveguide J. Appl. Phys. 79 4471
12. Lagomarsino S, Cedola A, Di Fonzo S, Jark W, Mocella V, Pelka J and Riekel C 2002 Advances in microdiffraction with x-ray waveguide Cryst. Res. Technol. 37 758
13. Lagomarsino S and Cedola A 2004 X-ray Microscopy and Nanodiffraction Encyclopedia of Nanoscience and Nanotechnology ed L Nalwa (Stevenson Ranch, CA: American Scientific Publishers) pp 681-710
14. Martin I, Muraglia A, Campanile G, Cancedda R and Quarto R 1997 Fibroblast growth factor-2 supports ex vivo expansion and maintenance of osteogenic precursors from human bone marrow Endocrinology 138 4456
15. Meneghini C, Dalconi M C, Nuzzo S, Mobilio S and Wenk R H 2003 Refinement on x-ray diffraction patterns of bioapatite in human fetal bones Biophys. J. 84 2021
16. Muller M, Burghammer M, Flot D, Riekel C, Morawe C, Murphy B and Cedola A 2000 Microcrystallography with X-ray waveguide J. Appl. Crystallogr. 33 1231
17. Muraglia A, Martin I, Cancedda R and Quarto R 1998 A nude mouse model for human bone formation in unloaded conditions Bone 22 131S
18. Quarto R, Mastrogiacomo M, Cancedda R, Kutepov S M, Mukhachev V, Lavroukov A, Kon E and Marcacci M 2001 Repair of large bone defects with the use of autologous bone marrow stromal cells N. Engl. J. Med. 344 385
19. Rinnerthaler S, Roschger P, Jakob H F, Nader A, Klaushofer K and Fratzl P 1999 Scanning small angle X-ray scattering analysis of human bone sections Calcif. Tissue Int. 64 422
20. Su X, Sun K, Cui F Z and Landis W J 2003 Organization of apatite crystals in human woven bone Bone 32 150-62
21. Zizak I, Paris O, Roschger P, Bernstorff S, Amenitsch H, Klaushofer K and Fratzl P 2000 Investigation of bone and cartilage by synchrotron scanning-SAXS and WAXS with micrometer spatial resolution J. Appl. Crystallogr. 33 820
22. Zizak I, Roschger P, Paris O, Misof B M, Berzlanovich A, Bernstorff S, Amenitsch H, Klaushofer K and Fratzl P 2003 Characteristics of mineral particles in the human bone/cartilage interface J. Struct. Biol. 141 208