Pomegranate flower extract diminishes cardiac fibrosis in zucker diabetic fatty rats: Modulation of cardiac endothelin-1 and nuclear factor-kappaB pathways

Journal of Cardiovascular Pharmacology

Volumn 46, Issue 6, 2005, Pages 856-862

  Huang, Tom H W ^a   Yang, Qinglin ^b   Harada, Masaki ^c   Li, George Q ^a   Yamahara, Johji ^d   Roufogalis, Basil D ^a   Li, Yuhao ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b MOREHOUSE SCHOOL OF MEDICINE   (United States)

^c KYOTO UNIVERSITY   (Japan)

^d Pharmafood Institute   (Japan)

Author keywords

Diabetes; Endothelin; Fibrosis; Heart; NF kappaB; Pomegranate

Indexed keywords

ANTIDIABETIC AGENT; COLLAGEN; COLLAGEN TYPE 1; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; FIBRONECTIN; GALLIC ACID; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; OLEANOLIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN C JUN; PUNICA GRANATUM EXTRACT; URSOLIC ACID; PLANT EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CONTROLLED STUDY; CORONARY ARTERY; DIABETES MELLITUS; DRUG ISOLATION; DRUG MECHANISM; FIBROBLAST; FLOWER; GENE EXPRESSION; HEART FUNCTION; HEART LEFT VENTRICLE; HEART MUSCLE FIBROSIS; HYPERGLYCEMIA; HYPERLIPIDEMIA; MACROPHAGE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POMEGRANATE; PRIORITY JOURNAL; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; STAINING; ANIMAL; BODY WEIGHT; CELL LINE; DRUG EFFECT; FIBROSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HEART; HEART MUSCLE; METABOLISM; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORGAN SIZE; PATHOLOGY; ZUCKER RAT;

ANIMALS; BODY WEIGHT; CELL LINE; DIABETES MELLITUS, TYPE 2; ENDOTHELIN-1; FIBROSIS; FLOWERS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEART; MALE; MICE; MYOCARDIUM; NF-KAPPA B; OBESITY; ORGAN SIZE; PLANT EXTRACTS; PUNICACEAE; RATS; RATS, ZUCKER;

EID: 33644681193     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fjc.0000190489.85058.7e     Document Type: Article

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