DNA intramolecular triplexes containing dT → du substitutions: Unfolding energetics and ligand binding

Biochemistry

Volumn 45, Issue 9, 2006, Pages 3051-3059

  Soto, Ana Maria ^a,c   Rentzeperis, Dionisios ^a,d   Shikiya, Ronald ^a,e   Alonso, Michelle ^a   Marky, Luis A ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c The College of New Jersey   (United States)

^d Development LLC   (United States)

^e CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; CALORIMETERS; CONCENTRATION (PROCESS); ENTHALPY; HYDROPHOBIC CHROMATOGRAPHY; SCANNING; SPECIFIC HEAT; STABILIZATION; STACKING FAULTS; THERMODYNAMIC STABILITY;

BINDING ENTHALPY; DESTABILIZING EFFECT; ELECTRONIC EFFECT; HEAT CAPACITY EFFECT; HYDROPHOBIC GROOVE; INTRAMOLECULAR TRIPLEXES; LOWER UNFOLDING ENTHALPIES; MINOR GROOVE; SALT CONCENTRATION; UNFOLDING ENERGETICS AND LIGAND BINDING;

DNA;

CONGOCIDINE; DEOXYURIDINE; METHYL GROUP; THYMIDINE; URIDINE;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; DIFFERENTIAL SCANNING CALORIMETRY; DNA DENATURATION; DNA STRUCTURE; ENERGY TRANSFER; ENTHALPY; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR INTERACTION; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; THERMODYNAMICS; THERMOSTABILITY; ULTRAVIOLET SPECTROSCOPY;

BINDING SITES; CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; DEOXYURIDINE; DNA; LIGANDS; NETROPSIN; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; THERMODYNAMICS; THYMIDINE;

EID: 33644676583     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052203b     Document Type: Article

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