RT-PCR determination of maspin and mammaglobin B in peripheral blood of healthy donors and breast cancer patients

Annals of Oncology

Volumn 17, Issue 3, 2006, Pages 424-428

  Mercatali, L ^a   Valenti, V ^a   Calistri, D ^a   Calpona, S ^a   Rosti, G ^b   Folli, S ^c   Gaudio, M ^c   Frassineti, G L ^c   Amadori, D ^c   Flamini, E ^c  

^a ISTITUTO ONCOLOGICO ROMAGNOLO   (Italy)

^b SANTA MARIA DELLE CROCI HOSPITAL   (Italy)

^c MORGAGNI PIERANTONI HOSPITAL   (Italy)

Author keywords

Breast cancer; Mammaglobin B; Maspin; Peripheral blood; RT PCR

Indexed keywords

BIOLOGICAL MARKER; MAMMAGLOBIN; MASPIN; RNA;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BREAST CANCER; CANCER PATIENT; CANCER RELAPSE; CANCER RISK; CANCER STAGING; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DONOR; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; NON INVASIVE MEASUREMENT; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA PRIMERS; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; MIDDLE AGED; NEOPLASM PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SERPINS; TUMOR MARKERS, BIOLOGICAL; UTEROGLOBIN;

EID: 33644673751     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdj109     Document Type: Article

References (38)

1. Landis SH, Murray T, Bolden S, Wingo PA. Cancer Statistics. CA Cancer J Clin 1998; 48: 6-29.
2. Henderson BE, Ross RK, Pike MC. Toward the primary prevention of cancer. Science 1991; 254: 1131-1137.
3. Chu KC, Tarone RE, Kessler LG et al. Recent trends in US breast cancer incidence, survival and mortality rates. J Natl Cancer Inst 1996; 88: 1571-1579.
4. Hortobagyi GN. Treatment of breast cancer. New Engl J Med 1998; 14: 974-984.
5. Ross AA, Cooper BW, Lazarus HL et al. Detection and viability of tumor cells in peripheral blood stem cell collections from breast cancer patients using immunocytochemical and clonogenic assay techniques. Blood 1993; 82: 2605-2610.
6. Schulze R, Schulze M, Wischnik A et al. Tumor cell contamination of peripheral blood stem cell transplants and bone marrow in high-risk breast cancer patients. Bone Marrow Transplant 1997; 19: 1223-1228.
7. Judkins T, Hendrickson BC, Deffenbaugh AM, Scholl T. Single nucleotide polymorphisms in clinical genetic testing: The characterization of the clinical significance of genetic variants and their application in clinical research for BRCA1. Mutat Res 2005; 573: 168-179.
8. Stathopoulou A, Mavroudis D, Perraki M et al. Molecular detection of cancer cells in the peripheral blood of patients with breast cancer: comparison of CK-19, CEA and maspin as detection markers. Anticancer Res 2003; 23: 1883-1890.
9. Grunewald K, Haun M, Urbanek M et al. Mammaglobin gene expression: A superior marker of breast cancer cells in peripheral blood in comparison to epidermal-growth-factor receptor and cytokeratin-19. Lab Invest 2000; 80: 1071-1077.
10. Stathopoulou A, Vlachonikolis I, Mavroudis D et al. Molecular detection of cytokeratin-19-positive cells in the peripheral blood of patients with operable breast cancer: Evaluation of their prognostic significance. J Clin Oncol 2002; 20: 3404-3412.
11. Salven P, Perhoniemi V, Tykka H et al. Serum VEGF levels in women with a benign breast tumor or breast cancer. Breast Cancer Res Treat 1999; 53: 161-166.
12. Granato AM, Nanni O, Falcini F et al. Basic fibroblast growth factor and vascular endothelial growth factor serum levels in breast cancer patients and healthy women: Useful as diagnostic tool? Breast Cancer Res 2004; 6: 38-45.
13. Heer K, Kumar H, Read JR et al. Serum vascular endothelial growth factor in breast cancer: Its relation with cancer type and estrogen receptor status. Clin Cancer Res 2001; 7: 3491-3494.
14. Osborne MP, Rosen PP. Detection and management of bone marrow micrometastases in breast cancer. Oncology (Huntingt) 1994; 8: 25-31.
15. Datta YH, Adams PT, Drobyski WR et al. Sensitive detection of occult breast cancer by the reverse transcriptase polymerase chain reaction. J Clin Oncol 1994; 12: 475-482.
16. Fields KK, Elfenbein GJ, Trudeau WL et al. Clinical significance of bone marrow metastases as detected using the polymerase chain reaction in patients with breast cancer undergoing high-dose chemotherapy and bone marrow transplantation. J Clin Oncol 1996; 14: 1868-1876.
17. Battaglia M, Pedrazzoli P, Palermo B et al. Epithelial tumor cell detection and the unsolved problems of nested RT-PCR: A new sensitive one step method without false positive results. Bone Marrow Transplant 1998; 22: 693-698.
18. Traystman MD, Cochran GT, Hake SJ et al. Comparison of molecular cytocheratin 19 reverse transcriptase polymerase chain reaction (CK19 RT-PCR) and immunocytochemical detection of micrometastatic breast cancer cells in hematopoietic harvests. J Hematother 1997; 6: 551-561.
19. Luppi M, Morselli M, Bandieri E et al. Sensitive detection of circulating breast cancer by reverse-transcriptase polymerase chain reaction of maspin gene. Ann Oncol 1996; 7: 619-624.
20. Sabbatini R, Federico M, Morselli M et al. Detection of circulating tumor cells by reverse transcriptase polymerase chain reaction of maspin in patients with breast cancer undergoing conventional-dose chemotherapy. J Clin Oncol 2000; 18: 1914-1920.
21. Corradini P, Voena C, Astolfi M et al. Maspin and mammaglobin genes are specific markers for RT-PCR detection of minimal residual disease in patients with breast cancer. Ann Oncol 2001; 12: 1693-1698.
22. Manzotti M, Dell'Orto P, Maisonneuve P et al. Reverse transcription-polymerase chain reaction assay for multiple mRNA markers in the detection of breast cancer metastases in sentinel lymph nodes. Int J Cancer 2001; 95: 307-312.
23. Aihara T, Fujiwara Y, Ooka M et al. Mammaglobin B as a novel marker for detection of breast cancer micrometastases in axillary lymph nodes by reverse transcription-polymerase chain reaction. Breast Cancer Res Treat 1999; 58: 137-140.
24. Marchetti A, Buttitta F, Bertacca G et al. mRNA markers of breast cancer nodal metastases: Comparison between mammaglobin and carcinoembryonic antigen in 248 patients. J Pathol 2001; 195: 186-190.
25. Cerveira N, Torres L, Rocha P et al. Highly sensitive detection of the MGB1 transcript (mammaglobin) in the peripheral blood of breast cancer patients. Int J Cancer 2004; 108: 592-595.
26. Zach O, Kasparu H, Krieger O et al. Detection of circulating mammary carcinoma cells in the peripheral blood of breast cancer patients via a nested reverse transcriptase polymerase chain reaction assay for mammaglobin mRNA. J Clin Oncol 1999; 17: 2015-2019.
27. Zach O, Kasparu H, Wagner H et al. Prognostic value of tumor cell detection in peripheral blood of breast cancer patients. Acta Med Austriaca Suppl 2002; 59: 2-4.
28. Silva AL, Tome MJ, Correia AE, Passos-Coelho JL. Human mammaglobin RT-PCR assay for detection of occult breast cancer cells in hematopoietic products. Ann Oncol 2002; 13: 429-442.
29. Ricotti L, Barzanti F, Amadori D et al. Combined 4-hydroxy-ifosfamide and vinorelbine treatment in established and primary human breast cell cultures. Ann Oncol 2000; 11: 587-594.
30. Stathopoulou A, Vlachonikolis I, Mavroudis D et al. Molecular detection of cytokeratin-19-positive cells in the peripheral blood of patients with operable breast cancer: Evaluation of their prognostic significance. J Clin Oncol 2002; 20: 3404-3412.
31. Lòpez-Guerrero JA, Gilabert PB, Barragan Gonzales E et al. Use of reverse-transcriptase polymerase chain reaction (RT-PCR) for carcinoembryonic antigen, cytokeratin 19, and maspin in the detection of tumor cells in leukapheresis products from patients with breast cancer: comparison with immunocytochemistry. J Hematother 1999; 8: 53-61.
32. Min JC, Tafra L, Verbanac K. Identification of superior markers for polymerase chain reaction detection of breast cancer metastases in sentinel lymph nodes. Cancer Res 1998; 58: 4581-4584.
33. Ballestrero A, Coviello DA, Garuti A et al. Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination. Cancer 2001; 92: 2030-2035.
34. Bosma AJ, Weigelt B, Lambrechts AC et al. Detection of circulating breast tumor cells by differential expression of marker genes. Clin Cancer Res 2002; 8: 1871-1877.
35. Baker MK, Mikhitarian K, Osta W et al. Molecular detection of breast cancer cells in the peripheral blood of advanced-stage breast cancer patients using multimarker real-time reverse transcription-polymerase chain reaction and a novel porous barrier density gradient centrifugation technology. Clin Cancer Res 2003; 9: 4865-4871.
36. Mitas M, Mikhitarian K, Walters C et al. Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel. Int J Cancer 2001; 2: 162-171.
37. Ko Y, Grunewald E, Totzke et al. High percentage of false-positive results of cytokeratin 19 RT-PCR in blood: A model for the analysis of illegitimate gene expression. Oncology 2000; 59: 81-88.
38. Ballestrero A, Garuti A, Bertolotto M et al. Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: Possible relevance to the assays for the detection of micrometastatic breast cancer. Br J Cancer 2005; 92: 1948-1952.