Ghrelin-stimulation test in the diagnosis of canine pituitary dwarfism

Research in Veterinary Science

Volumn 81, Issue 1, 2006, Pages 24-30

  Bhatti, Sofie F M ^a   De Vliegher, S P ^a   Mol, J A ^b   Van Ham, L M L ^a   Kooistra, H S ^b  

^a GHENT UNIVERSITY   (Belgium)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Dog; Growth hormone deficiency; Growth hormone secretagogue; Hyposomatotropism; Pituitary gland

Indexed keywords

ADENOHYPOPHYSIS HORMONE; CORTICOTROPIN; GHRELIN; GROWTH HORMONE; HYDROCORTISONE; HYPOPHYSIS HORMONE; LUTEINIZING HORMONE; PROLACTIN; THYROTROPIN;

ARTICLE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DIAGNOSTIC VALUE; DOG DISEASE; FALSE NEGATIVE RESULT; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE DEFICIENCY; HORMONE RELEASE; HYDROCORTISONE BLOOD LEVEL; LUTEINIZING HORMONE BLOOD LEVEL; NONHUMAN; PITUITARY DWARFISM; PROVOCATION TEST; THYROTROPIN BLOOD LEVEL;

ANIMALS; DOG DISEASES; DOGS; DWARFISM, PITUITARY; FALSE NEGATIVE REACTIONS; FEMALE; GROWTH HORMONE; INFUSIONS, INTRAVENOUS; MALE; PEPTIDE HORMONES; SENSITIVITY AND SPECIFICITY;

CANIS FAMILIARIS;

EID: 33644660821     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2005.09.009     Document Type: Article

References (46)

1. G. Aimaretti C. Baffoni F. Broglio J.A. Janssen G. Corneli R. Deghenghi A.J. Van Der Lely E. Ghigo E. Arvat Endocrine responses to ghrelin in adult patients with isolated childhood-onset growth hormone deficiency Clinical Endocrinology 56 2002 765-771
2. E. Andresen P. Willeberg Pituitary dwarfism in German shepherd dogs: additional evidence of simple, autosomal recessive inheritance Nordisk Veterinaer Medicin 28 1976 481-486
3. E. Arvat L. Di Vito F. Broglio M. Papotti G. Muccioli C. Dieguez F.F. Casanueva R. Deghenghi F. Cammanni E. Ghigo Preliminary evidence that ghrelin, the natural growth hormone secretagogue receptor ligand, strongly stimulates GH secretion in humans Journal of Endocrinological Investigation 23 2000 493-495
4. E. Arvat M. Maccario L. Di Vito F. Broglio A. Benso C. Gottero M. Papotti G. Muccioli C. Dieguez FF. Casanueva R. Deghenghi F. Camanni E. Ghigo Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: Comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone Journal of Clinical Endocrinology and Metabolism 86 2001 1169-1174
5. J.A. Ascacio-Martinez H.A. Barrera-Saldana A dog growth hormone cDNA codes for a mature protein identical to pig growth hormone Gene 143 1994 277-280
6. M.A. Bednarek S.D. Feighner S.S. Pong K.K. McKee D.L. Hreniuk M.V. Silva V.A. Warren A.D. Howard L.H. Van Der Ploeg J.V. Heck Structure-function studies on the new growth hormone-releasing peptide, ghrelin: Minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a Journal of Medicinal Chemistry 43 2000 4370-4376
7. S.F.M. Bhatti S.P. De Vliegher L. Van Ham H.S. Kooistra Effects of growth hormone-releasing peptides in healthy dogs and in dogs with pituitary-dependent hyperadrenocorticism Molecular and Cellular Endocrinology 197 2002 97-103
8. Bhatti, S.F.M., Duchateau, L., Van Ham, L.M.L., De Vliegher, S.P., Mol, J.A., Rijnberk, A., Kooistra, H.S., 2005. Effects of growth hormone secretagogues on the release of adenohypophyseal hormones in young and old healthy dogs. The Veterinary Journal, [Epub ahead of print].
9. C.Y. Bowers J. Chang F.A. Momany K. Folkers Effect of the enkephalins and enkephalin analogs on release of pituitary hormones in vitro G. MacIntyre H. Szelke Molecular Endocrinology 1977 Elsevier The Netherlands 287-292
10. F.F. Casanueva C. Dieguez Growth hormone secretagogues: Physiological role and clinical utility Trends in Endocrinology and Metabolism 10 1999 30-38
11. Y. Date M. Kojima H. Hosoda A. Sawaguchi M.S. Mondal T. Suganuma S. Matsukura K. Kangawa M. Nakazato Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastro intestinal tracts of rats and humans Endocrinology 141 2000 4255-4261
12. J.E. Eigenmann R.Y. Eigenmann Radioimmunoassay of canine growth hormone Acta Endocrinologica 98 1981 514-520
13. J.E. Eigenmann D.F. Patterson E.R. Froesch Body size parallels insulin-like growth factor I levels but not growth hormone secretory capacity Acta Endocrinologica (Copenh) 106 1984 448-453
14. E. Ghigo E. Arvat R. Giordano F. Broglio L. Gianotti M. Maccario G. Bisi A. Graziani M. Papotti G. Muccioli R. Deghenghi F. Camanni Biologic activities of growth hormone secretagogues in humans Endocrine Reviews 14 2001 87-93
15. M.S. Gill A.A. Toogood P.A. O'Neill M.O. Thorner S.M. Shalet P.E. Clayton Urinary growth hormone (GH), insulin-like growth factor I (IGF-I), and IGF-binding protein-3 measurements in the diagnosis of adult GH deficiency Journal of Clinical Endocrinology and Metabolism 83 1998 2562-2565
16. F. Hamann H.S. Kooistra J.A. Mol S. Gottschalk T. Bartels A. Rijnberk Pituitary function and morphology in two German shepherd dogs with congenital dwarfism Veterinary Record 144 1999 644-646
17. T. Hayashida K. Murakami K. Mogi M. Nishihara M. Nakazato M.S. Mondal Y. Horii M. Kojima K. Kangawa N. Murakami Ghrelin in domestic animals: distribution in stomach and its possible role Domestic Animal Endocrinology 21 2001 17-24
18. A.D. Howard S.D. Feighner D.F. Cully J.P. Arena P.A. Liberator C.I. Rosenblum M. Hamelin D.L. Hreniuk O.C. Playha J. Anderson P.S. Paress C. Diaz M. Chou K.K. Liu K.K. McKee S.S. Pong L.Y. Chaung A. Elbrecht M. Dashkevicz R. Heavens M. Rigby D.J. Sirinathsiinghji D.C. Dean D.G. Melillo L.H. Van de Ploeg A receptor in pituitary and hypothalamus that functions in growth hormone release Science 16 1996 974-977
19. C.M. Knottenbelt M.E. Herrtage Use of proligestone in the management of three German shepherd dogs with pituitary dwarfism Journal of Small Animal Practice 43 2002 164-170
20. M. Kojima H. Hosoda Y. Date M. Nakazato H. Matsuo K. Kangawa Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature 402 1999 656-660
21. H.S. Kooistra G. Voorhout P.J. Selman A. Rijnberk Progestin-induced growth hormone (GH) production in the treatment of dogs with congenital GH deficiency Domestic Animal Endocrinology 15 1998 93-102
22. H.S. Kooistra G. Voorhout J.A. Mol A. Rijnberk Combined pituitary hormone deficiency in German shepherd dogs with dwarfism Domestic Animal Endocrinology 19 2000 177-190
23. I.S. Lantinga-van Leeuwen J.A. Mol H.S. Kooistra A. Rijnberk M. Breen C. Renier B.A. van Oost Cloning of the canine gene encoding transcription factor Pit-1 and its exclusion as candidate gene in a canine model of pituitary dwarfism Mammalian Genome 11 2000 31-36
24. I.S. Lantinga-van Leeuwen H.S. Kooistra J.A. Mol C. Renier M. Breen B.A. van Oost Cloning, characterization, and physical mapping of the canine Prop-1 gene (PROP1): Exclusion as a candidate for combined pituitary hormone deficiency in German shepherd dogs Cytogenetics and Cell Genetics 88 2000 140-144
25. L. Lazarus A guide to diagnosis R.A. Donald Endocrine Disorders 1984 Marcel Dekker, Inc. New York 273
26. C.D. Lothrop Pathophysiology of growth-hormone responsive dermatosis Compendium on Continuing Education for the Practicing Veterinarian 10 1988 1346
27. A.F. Massoud P.C. Hindmarsh D.G.D. Brook Hexarelin-induced growth hormone, cortisol and prolactin release: A dose-response study Journal of Clinical Endocrinology and Metabolism 81 1996 4338-4341
28. K.K. McKee O.C. Palyha S.D. Feighner D.L. Hreniuk C.P. Tan M.S. Phillips R.G. Smith L.H. Van der Ploeg A.D. Howard Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors Molecular Endocrinology 11 1997 415-423
29. B.P. Meij J.A. Mol M.M. Bevers A. Rijnberk Alterations in anterior pituitary function of dogs with pituitary-dependent hyperadrenocorticism Journal of Endocrinology 154 1997 505-512
30. J.A. Mol S.C. Henzen-Logmans P. Hageman W. Misdorp M.A. Blankenstein A. Rijnberk Expression of the gene encoding growth hormone in the human mammary gland Journal of Clinical Endocrinology and Metabolism 80 1995 3094-3096
31. R.C. Nap J.A. Mol H.A. Hazewinkel Age-related plasma concentrations of growth hormone (GH) and insulin-like growth factor I (IGF-I) in Great Dane pups fed different dietary levels of protein Domestic Animal Endocrinology 10 1993 237-247
32. T.M. Nett A.M. Akbar R.D. Phemister P.A. Holst L.E. Reichert G.D. Niswender Levels of luteinizing hormone, estradiol and progesterone in serum during the estrous cycle and pregnancy in the Beagle bitch Proceedings of the Society for Experimental Biology and Medicine 148 1975 134-139
33. A.C. Okkens S.J. Dieleman M.M. Bevers A.H. Willemse Evidence for the non-involvement of the uterus in the lifespan of the corpus luteum in the cyclic dog Veterinary Quarterly 7 1985 169-173
34. R. Peino R. Baldelli J. Rodriguez-Garcia S. Rodriguez-Segade M. Kojima K. Kangawa E. Arvat E. Ghigo C. Dieguez F.F. Casanueva Ghrelin-induced growth hormone secretion in humans European Journal of Endocrinology 143 2000 11-14
35. S.S. Pong L.Y.P. Chaung D.C. Dean R.P. Nargund A.A. Patchett R.G. Smith Identification of a new G-protein-linked receptor for growth hormone secretagogues Molecular Endocrinology 10 1996 57-61
36. P.M. Plotsky W. Vale Patterns of growth hormone-releasing factor and somatostatin secretion into the hypophysial-portal circulation of the rat Science 230 1985 461-463
37. A. Rijnberk H. van Herpen J.A. Mol G.R. Rutteman Disturbed release of growth hormone in mature dogs: A comparison with congenital growth hormone deficiency Veterinary Record 27 1993 542-545
38. S. Romagnoli P.W. Concannon Clinical use of progestins in bitches and queens: A review P.W. Concannon G. England J. Verstegen C. Linde-Forsberg Recent Advances in Small Animal Reproduction 2003 International Veterinary Information Service Ithaca, NY 1-17
39. P.J. Selman J.A. Mol G.R. Rutteman E. van Garderen A. Rijnberk Progestin-induced growth hormone excess in the dog originates in the mammary gland Endocrinology 134 1994 287-292
40. K. Takaya H. Ariyasu N. Kanamoto H. Iwakura A. Yoshimoto M. Harada K. Mori Y. Komatsu T. Usui A. Shimatsu Y. Ogawa K. Hosoda T. Akamizu M. Kojima K. Kangawa K. Nakao Ghrelin strongly stimulates growth hormone release in humans Journal of Clinical Endocrinology and Metabolism 85 2000 4908-4911
41. G.B. Thomas K.M. Fairhall I.C.A.F. Robinson Activation of the hypothalamo-pituitary-adrenal axis by the growth-hormone (GH) secretagogue, GH-releasing peptide-6, in rats Endocrinology 138 1997 1585-1591
42. C. Tomasetto C. Wendling M.C. Rio P. Poitras Identification of cDNA encoding motilin related peptide/ghrelin precursor from dog fundus Peptides 22 2001 2055-2059
43. E. van Garderen M. de Wit W.F. Voorhout G.R. Rutteman J.A. Mol H. Nederbragt W. Misdorp Expression of growth hormone in canine mammary tissue and mammary tumors. Evidence for a potential autocrine/paracrine stimulatory loop American Journal of Pathology 150 1997 1037-1047
44. H. van Herpen A. Rijnberk J.A. Mol Production of antibodies to biosynthetic human growth hormone in the dog Veterinary Record 134 1994 171
45. B.A. van Oost S.A. Versteeg S. Imholz H.S. Kooistra Exclusion of the lim homeodomain gene LHX4 as a candidate gene for pituitary dwarfism in German shepherd dogs Molecular and Cellular Endocrinology 29 2002 57-62
46. Yu, H., Cassorla, F., Tiulpakov, A., 1998. A double blind placebo-controlled efficacy trial of an oral growth hormone (GH) secretagogue (MK-0677) in GH deficient (GHD) children. Endocrine Society 1998 Abstract Book, p. 8.