메뉴 건너뛰기




Volumn 2, Issue 20, 2000, Pages 3173-3176

A facile stereocontrolled synthesis of anti-α-(trifluoromethyl)-β-amino alcohols

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; ALDEHYDE; AMINOALCOHOL; BORONIC ACID DERIVATIVE; CINNAMALDEHYDE; DRUG DERIVATIVE; OZONE;

EID: 0034609673     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol000195f     Document Type: Article
Times cited : (98)

References (51)
  • 2
    • 0003314351 scopus 로고    scopus 로고
    • Biomedical frontiers of fluorine chemistry
    • American Chemical Society: Washington, DC
    • (b) Biomedical Frontiers of Fluorine Chemistry; Ojima, I., McGrath, J. R., Welch, J. T., Eds.; ACS Symposium Series 639, American Chemical Society: Washington, DC, 1996.
    • (1996) ACS Symposium Series 639 , vol.639
    • Ojima, I.1    McGrath, J.R.2    Welch, J.T.3
  • 30
    • 0042189438 scopus 로고    scopus 로고
    • note
    • Typical Reaction Procedure. To a solution of the aldehyde 5 in EtOH was added the amine 3a and 2-furylboronic acid (4a) successively. The reaction mixture was sealed and stirred at room temperature for 24 h. After concentration under vacuum, the residue was purified by chromatography with hexanes/ethyl acetate (9:1) to yield 6a as colorless oil (560 mg, 85% yield, >99% de).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.