Molecular modeling of SWR-0342SA, a β3-selective agonist, with β1- and β3-adrenoceptor

Life Sciences

Volumn 78, Issue 17, 2006, Pages 2019-2023

  Ahmed, Maruf ^a   Ishiguro, Masaji ^b   Nagatomo, Takafumi ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

Author keywords

adrenoceptors; Molecular modeling; SWR 0342SA

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; CYANOPINDOLOL I 125; ISOPRENALINE; RADIOLIGAND; RHODOPSIN; SWR 0342SA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL STRAIN COS7; CONTROLLED STUDY; DRUG INHIBITION; DRUG RECEPTOR BINDING; ELECTRICITY; HYDROPHOBICITY; LIGAND BINDING; MAMMAL CELL; MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; RADIOASSAY; SIMULATION;

ACETIC ACIDS; ADRENERGIC BETA-AGONISTS; ANIMALS; BINDING SITES; CERCOPITHECUS AETHIOPS; COS CELLS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-3;

ANIMALIA; MAMMALIA;

EID: 33644629877     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.09.023     Document Type: Article

References (20)

1. J.P. Bilezikian, A.M. Dornfeld, and D.E. Gammon Structure binding activity analysis of beta-adrenergic amines: I. Binding to the beta receptor and activation of adenylate cyclase Biochemical Pharmacology 27 1978 1445 1454
2. B. Borhan, M.L. Souto, H. Imai, Y. Shichida, and K. Nakanishi Movement of retinal along the visual transduction path Science 288 2000 2209 2212
3. 50) of an enzymatic reaction Biochemical Pharmacology 22 1973 3099 3108
4. B.R. Cullen Use of eukaryotic expression technology in the functional analysis of a cloned genes S.L. Berger A.R. Kimmel Methods in Enzymology 1987 Academic Press San Diego, CA 684 704
5. D.L. Farrens, C. Altenbach, K. Yang, W.L. Hubbell, and H.G. Khorana Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin Science 274 1996 768 770
6. 3-adrenergic receptor messenger ribonucleic -acids Endocrinology 135 1994 1025 1031
7. M. Ishiguro Ligand-binding modes in cationic biogenic amine receptors ChemBioChem 5 2004 1210 1219
8. M. Ishiguro, Y. Oyama, and T. Hirano Structural models of the photointermediates in the rhodopsin photocascade, lumirhodopsin, metarhodopsin I, and metarhodopsin II ChemBioChem 5 2004 298 310
9. 2-adrenergic receptor for high affinity binding of salmeterol Molecular Pharmacology 54 1998 616 622
10. 2-selective agonist TA-2005 Molecular Pharmacology 53 1998 128 134
11. T. Kiso, T. Namikawa, T. Tokunaga, K. Sawada, T. Kakita, T. Shogaki, and Y. Ohtsubo Anti-obesity and anti-diabetic activities of a new β 3-adrenergic receptor agonist, (S)-(Z)-[4-[[1-[2-[(2-hydroxy-3-phenoxypropyl)] amino]ethyl]-1-propenyl] phenoxy] acetic acid ethanedioic acid (SWR-0342SA), in KK-Ay mice Biological and Pharmaceutical Bulletin 22 1999 1073 1078
12. 2 adrenergic receptors to bind subtype selective agonists Life Sciences 62 1998 1513 1517
13. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent Journal of Biological Chemistry 193 1951 265 275
14. B.G. Main, and H. Tucker Recent advances in β-adrenergic blocking agents Progress in Medicinal Chemistry 22 1985 121 164
15. S. Mizushima, and S. Nagata pEF-BOS, a powerful mammalian expression vector Nucleic Acids Research 18 1990 5322
16. K. Palczewski, T. Kumasaka, T. Hori, C.A. Behnke, H. Motoshima, B.A. Fox, I. Le Trong, D.C. Teller, T. Okada, R.E. Stenkamp, M. Yamamoto, and M. Miyano Crystal structure of rhodopsin: A G protein-coupled receptor Science 289 2000 739 745
17. 2-adrenergic receptor-Extending the ternary complex model Journal of Biological Chemistry 268 1993 4625 4636
18. Y. Sato, H. Kurose, M. Isogaya, and T. Nagao Molecular characterization of pharmacological properties of T-0509 for β-adrenoceptors European Journal of Pharmacology 315 1996 363 367
19. C.D. Strader, T.M. Fong, M.R. Tota, D. Underwood, and R.A.F. Dixon Structure and function of G protein-coupled receptors Annual Review of Biochemistry 63 1994 101 132
20. 3- adrenergic receptors Annual Review of Pharmacology and Toxicology 37 1997 421 450