The C-terminal tail of protein kinase D2 and protein kinase D3 regulates their intracellular distribution

Biochemical and Biophysical Research Communications

Volumn 342, Issue 3, 2006, Pages 685-689

  Papazyan, Romeo ^a   Rozengurt, Enrique ^a   Rey, Osvaldo ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

G protein coupled receptor; Green fluorescent protein; Imaging; Intracellular distribution; Protein kinase C; Protein kinase D; Protein kinase D2; Protein kinase D3

Indexed keywords

GREEN FLUORESCENT PROTEIN; PROTEIN KINASE; PROTEIN KINASE D; PROTEIN KINASE D2; PROTEIN KINASE D3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENZYME REGULATION; HUMAN; HUMAN CELL; INFORMATION PROCESSING; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN KINASE C; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SWISS 3T3 CELLS;

ANIMALIA;

EID: 33644621946     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.02.013     Document Type: Article

References (18)

1. E. Rozengurt, O. Rey, and R.T. Waldron Protein kinase D signaling J. Biol. Chem. 280 2005 13205 13208
2. S. Jaken Protein kinase C isozymes and substrates Curr. Opin. Cell Biol. 8 1996 168 173
3. A.C. Newton Regulation of protein kinase C Curr. Opin. Cell Biol. 9 1997 161 167
4. M.N. Teruel, and T. Meyer Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction Cell 103 2000 181 184
5. S. Matthews, T. Iglesias, D. Cantrell, and E. Rozengurt Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: dissociation from PKD activation FEBS Lett. 457 1999 515 521
6. J. Prestle, K. Pfizenmaier, J. Brenner, and F.J. Johannes Protein kinase C mu is located at the Golgi compartment J. Cell Biol. 134 1996 1401 1410
7. O. Rey, S.H. Young, D. Cantrell, and E. Rozengurt Rapid protein kinase D translocation in response to G protein-coupled receptor activation: dependence on protein kinase C J. Biol. Chem. 276 2001 32616 32626
8. P. Storz, A. Hausser, G. Link, J. Dedio, B. Ghebrehiwet, K. Pfizenmaier, and F.J. Johannes Protein kinase Cμ is regulated by the multifunctional chaperon protein p32 J. Biol. Chem. 275 2000 24601 24607
9. O. Rey, J. Sinnett-Smith, E. Zhukova, and E. Rozengurt Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation J. Biol. Chem. 276 2001 49228 49235
10. O. Rey, E. Zhukova, J. Sinnett-Smith, and E. Rozengurt Vasopressin-induced intracellular redistribution of protein kinase D in intestinal epithelial cells J. Cell. Physiol. 196 2003 483 492
11. 12, Rho, filamin-A and the actin cytoskeleton J. Biol. Chem. 280 2005 22875 22882
12. O. Rey, J. Yuan, and E. Rozengurt Intracellular redistribution of protein kinase D2 in response to G-protein coupled receptor agonists Biochem. Biophys. Res. Commun. 302 2003 817 824
13. O. Rey, J.R. Reeve Jr., E. Zhukova, J. Sinnett-Smith, and E. Rozengurt G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: depende onn plasma membrane translocation and protein kinase Cε J. Biol. Chem. 279 2004 34361 34372
14. O. Rey, J. Yuan, S.H. Young, and E. Rozengurt Protein kinase Cν/protein kinase D3 nuclear localization, catalytic activation, and intracellular redistribution in response to G protein-coupled receptor agonists J. Biol. Chem. 278 2003 23773 23785
15. O. Rey, R. Papazyan, R.T. Waldron, S.H. Young, J. Lippincott-Schwartz, R. Jacamo, E. Rozengurt, The nuclear import of protein kinase D3 requires its catalytic activity, J. Biol. Chem., in press at < www.jbc.org/cgi/content/ abstract/M508014200v1 /〉.
16. D.A. Jans, C.K. Chan, and S. Huebner Signals mediating nuclear targeting and their regulation: application in drug delivery Med. Res. Rev. 18 1998 189 223
17. R.H. Kehlenbach, A. Dickmanns, and L. Gerace Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT in vitro J. Cell Biol. 141 1998 863 874
18. J.D. Thompson, D.G. Higgins, and T.J. Gibson CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Nucleic Acids Res. 22 1994 4673 4680