Reproductive aspects of celiac disease;Aspetti riproduttivi della malattia celiaca

Annali Italiani di Medicina Interna

Volumn 20, Issue 3, 2005, Pages 143-157

  Stazi, Anna Velia ^a   Trinti, Biagino ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Abortion; Celiac disease; Female infertility; Hormones; Male infertility; Malformations; Nutritional deficiency; Pregnancy; Spermatogenesis

Indexed keywords

CELIAC DISEASE; DIET THERAPY; FEMALE; FEMALE INFERTILITY; FOLIC ACID DEFICIENCY; HUMAN; IRON DEFICIENCY ANEMIA; MALE; MALE INFERTILITY; OSTEOPOROSIS; PREGNANCY; REVIEW; SPONTANEOUS ABORTION; TREATMENT OUTCOME; VITAMIN K DEFICIENCY;

ABORTION, SPONTANEOUS; ANEMIA, IRON-DEFICIENCY; CELIAC DISEASE; FEMALE; FOLIC ACID DEFICIENCY; HUMANS; INFERTILITY, FEMALE; INFERTILITY, MALE; MALE; OSTEOPOROSIS; PREGNANCY; TREATMENT OUTCOME; VITAMIN K DEFICIENCY;

EID: 33644618670     PISSN: 03939340     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (95)

1. Rossi T. Celiac disease. Adolesc Med Clin 2004; 15: 91-103.
2. Sollid LM. Genetics of the immune response to gluten in coeliac disease. Dig Dis 1998; 16: 345-7.
3. Fornaroli F, Drago S, Di Pierro MR, Catassi C, Fasano A. Celiac disease: a world in exploration. Minerva Pediatr 2003; 55: 23-31.
4. Cronin CC, Shanahan F. Why is celiac disease so common in Ireland? Perspect Biol Med 2001; 44: 342-52.
5. Esposito C, Paparo F, Caputo I, et al. Expression and enzymatic activity of small intestinal tissue trasglutaminase in celiac disease. Am J Gastroenterol 2003; 98: 1813-20.
6. Caputo I, D'Amato A, Troncone R, Auricchio S, Esposito C. Transglutaminase 2 in celiac disease. Minireview article. Amino Acids 2004; 26: 381-6.
7. Thompson T. Wheat starch, gliadin, and the gluten-free diet. J Am Diet Assoc 2001; 101: 1456-9.
8. Stazi AV, Mantovani A. La malattia celiaca: fattore di rischio per la donna in età fertile. Minerva Ginecologica 2000; 52: 189-96.
9. Stazi AV, Mantovani A. A risk factor for female fertility and pregnancy: celiac disease. Gynecol Endocrinol 2000; 14: 454-63.
10. Stazi AV, Mantovani A. Malattia celiaca e implicazioni endocrine e nutrizionali nella riproduzione maschile. Minerva Med 2004; 95: 243-54.
11. Iughetti L, Bulgarelli S, Forese S, Lorini R, Balli F, Bernasconi S. Endocrine aspects of coeliac disease. J Pediatr Endocrinol Metabol 2003; 16: 805-18.
12. Sategna Guidetti C, Solerio E, Scaglione N, Aimo G, Mengozzi. Duration of gluten exposure in adult coeliac disease does not correlate with the risk for autoimmune disorders. Gut 2001; 49: 502-5.
13. Bianchi ML, Bardella MT. Bone and celiac disease. Calcif Tissue Int 2002; 71: 465-71.
14. Sandmberg-Bennich S, Dahlquist G, Kallen B. Coeliac disease is associated with intrauterine growth and neonatal infections. Acta Paediatr 2002; 91: 30-3.
15. Ludvigsson JF, Ludvigsson J. Stressful life events, social support and confidence in the pregnant woman and risk coeliac disease in the offspring. Scand J Gastroenterol 2003; 38: 516-21.
16. Ciacci C, Cirillo M, Auriemma G, Di Dato G, Sabbatini F, Mazzacca G. Celiac disease and pregnancy outcome. Am J Gastroenterol 1996; 91: 718-22.
17. Stazi AV, Mantovani A. Possibili modelli animali delle complicanze endocrine, immunologiche e riproduttive della malattia celiaca. Minerva Med 2002; 93: 457-70.
18. Bottaro G, Cataldo F, Rotolo N, Spina M, Corazza GR. The clinical pattern of subclinical/silent celiac disease: an analysis on 1026 consecutive cases. Am J Gastroenterol 1999; 94: 691-6.
19. Sher KS, Jayanthi V, Probert CS, Stewart CR, Maybarry JF. Infertility, obstetric and gynaecological problems in coeliac sprue. Dig Dis 1994; 12: 186-90.
20. Foschi F, Diani F, Zardini E, Zanoni G, Caramaschi P. Celiac disease and spontaneous abortion. Minerva Ginecol 2002; 54: 151-9.
21. Collin P, Vilska S, Heinonen PK, Hallstrom O, Pikkarinen P. Infertility and coeliac disease. Gut 1996; 39: 382-4.
22. Machac S, Kolek A, Dostal J, et al. Celiac disease and fertility disorders in women. Ceska Gynekol 2003; 68: 80-3.
23. Ogborn AD. Pregnancy in patients with coeliac disease. Brit J Obstet Gynaecol 1975; 82: 293-6.
24. Sher KS, Mayberry JF. Female fertility, obstetric and gynaecological history in coeliac disease. A case-control study. Digestion 1994; 55: 243-6.
25. Molteni N, Bardella MT, Bianchi PA. Obstetric and gynecological problems in women with untreated celiac sprue. J Clin Gastroenterol 1990; 12: 37-9.
26. Eastell R. Management of osteoporosis due to ovarian failure. Med Pediatr Oncol 2003; 41: 222-7.
27. Michael M. Recognizing and managing celiac disease in primary care. J Am Acad Nurse Pract 2003; 15: 108-14.
28. Eliakim R, Sherer DM. Celiac disease: fertility and pregnancy. Gynecol Obstet Invest 2001; 51: 3-7.
29. Szulc P, Delmas PD. Osteoporosis in the aged male. Presse Med 2002; 31 (Part 1): 1760-6.
30. Chiechi LM, Valerio T, Loizzi P. Postmenopausal osteoporosis and celiac disease. Clin Exp Obstet Gynecol 2002; 29: 187-8.
31. Nuti R, Martini G, Valenti R, Giovani S, Salvatori S, Avanzati A. Prevalence of undiagnosed coeliac disease sindrome in osteoporotic women. J Intern Med 2001; 250: 361-6.
32. Thomason K, West J, Logan RF, Coupland C, Holmes GK. Fracture experience of patients with celiac disease: a population based survey. Gut 2003; 52: 518-22.
33. West J, Logan RF, Card TR, Smith C, Hubbard R. Fracture risk in people with celiac disease: a population-based cohort study. Gastroenterology 2003; 125: 429-36.
34. Smecuol E, Maurino E, Vazquez H, et al. Gynecological and obstetric disorders in coeliac disease: frequent clinical onset during pregnancy or the puerperium. Eur J Gastroenterol Hepatol 1996; 8: 63-9.
35. Corrado F, Magazzu G, Sferlazzas C. Diagnosis of celiac disease in pregnancy and puerperium: think about it. Acta Obstet Gynecol Scand 2002; 81: 180-1.
36. Erdozain JC, Martin de Argila C, Cerezo E, Lizasoain J, Presa M. Adult celiac disease: reactivation during pregnancy and puerperium. Am J Gastroenterol 1993; 88: 1139-40.
37. Dickey W, Stewart F, Nelson J, McBreen G, McMillan SA, Porter KG. Screening for coeliac disease as a possible maternal risk factor for neural tube defect. Clin Genet 1996; 49: 107-8.
38. Dahele A, Ghosh S. Vitamin B12 deficiency in untreated celiac disease. Am J Gastroenterol 2001; 96: 745-50.
39. De Sandre G, Caramaschi P. Untreated celiac disease with bad outcome of three pregnancies followed by a fourth normal pregnancy after two years of gluten-free diet [letter]. Am J Gastroenterol 1996; 91: 2653.
40. Haslam N, Lock RJ, Unsworth DJ. Coeliac disease, anemia and pregnancy. Clin Lab 2001; 47: 467-9.
41. Jameson S. Zinc status in pregnancy: the effect of zinc therapy on perinatal mortality, prematurity and placental ablation. Ann NY Acad Sci 1993; 678: 178-92.
42. Stoll C, Dott B, Alembik Y, Koehl C. Maternal trace elements, vitamin B12, folic acid and fetal malformations. Reprod Toxicol 1999; 13: 53-7.
43. Hall J, Solehdin F. Folic acid for the prevention of congenital anomalies. Eur J Pediatr 1998; 157: 445-50.
44. Steen MT, Boddie AM, Fisher AJ, et al. Neural-tube defects are associated with low concentration of cobalamine (vitamin B12) in amniotic fluid. Prenat Diagn 1998; 18: 545-55.
45. Rothenberg SP. Increasing the dietary intake of folate: pros and cons. Semin Hematol 1999; 36: 65-74.
46. Menger H, Lin AE, Toriello HV, Bernert G, Spranger JW. Vitamin K deficiency embryopathy: a phenocopy of the warfarin embryopathy due to a disorder of embryonic vitamin K metabolism. Am J Med Genet 1997; 72: 129-34.
47. Reinken L, Zieglauer H, Berger H. Vitamin B6 nutriture of children with acute celiac disease, celiac disease in remission, and of children with normal duodenal mucosa. Am J Clin Nutr 1976; 29: 750-3.
48. Merrill AH, Herderson JM. Disease associated with defects in vitamin B6 metabolism or utilisation. Ann Rev Nutr 1987; 7: 137-56.
49. Jacobsson C, Granstrom G. Effects of vitamin B6 on beta- aminoproprionitrile-induced palatal cleft formation in the rat. Cleft Palate Craniofac J 1997; 34: 95-100.
50. Bona G, Marinello D, Oderda G. Mechanisms of abnormal puberty in coeliac disease. Horm Res 2002; 57 (Suppl 2): 63-5.
51. Howard MR, Turnbull AJ, Morley P, Hollier P, Webb R, Clarke A. A prospective study of the prevalence of undiagnosed celiac disease in laboratory defined iron and folate deficiency. J Clin Pathol 2002; 55: 754-7.
52. Ong DE, Takase S, Chytil F. Cellular vitamin A-binding proteins in the testis. Ann NY Acad Sci 1987; 513: 172-8.
53. Livera G, Rouiller-Fabre V, Pairault C, Levacher C, Habert R. Regulation and perturbation of testicular functions by vitamins A. Reproduction 2002; 124: 173-80.
54. Gaemers IC, van Pelt AM, van der Saag PT, de Rooij DG. Alltrans-4-oxo-retinoic acid: a potent inducer of in vivo proliferation of grown-arrested A spermatogonia in the vitamin Adeficient mouse testis. Endocrinology 1996; 137: 479-85.
55. Mohindra S, Yachha SK, Srivastava A, et al. Coeliac disease in Indian children: assessment of clinical, nutritional and pathologic characteristics. J Health Popul Nutr 2001; 19: 204-8.
56. Bensoussan K, Morales CR, Hermo L. Vitamin E deficiency causes incomplete spermatogenesis and affects the structural differentiation of epithelial cells of the epididymis in the rat. J Androl 1998; 19: 266-88.
57. Wilson MJ, Kaye D, Quach HT, Sinka AA, Vatassery GT. Effect of vitamin E deficiency on the growth and secretory function of the rat prostatic complex. Exp Mol Pathol 2003; 74: 267-5.
58. Deshpande UR, Joseph LJ, Patwardhan UN, Samuel AM. Effect of antioxidants (vitamin C, E and turmeric extract) on methimalazole induced hypothyroidism in rats. Indian J Exp Biol 2002; 40: 735-8.
59. Reynaert H, Debeuckelaere S, De Waele B, Meysman M, Goossens A, Devis G. The brown bowel syndrome and gastrointestinal adenocarcinoma: two complications of vitamin E deficiency in celiac sprue and chronic pancreatitis. J Clin Gastroenterol 1993; 16: 48-51.
60. Mauro A, Orsi L, Mortara P, Costa P, Schiffer D. Cerebellar syndrome in adult celiac with vitamin E deficiency. Acta Neurol Scand 1991; 84: 167-70.
61. Takenaka A, Takahasci S, Noguchi T. Effect of protein nutrition on insulin-like grown factor-I (IGF-I) receptor in various tissues of rats. J Nutr Sci Vitaminol 1996; 42: 347-57.
62. Keene DE, Suescun MO, Bostwick MG, Chandrashekar V, Bartke A, Kopchick JJ. Puberty is delayed in male growth hormone receptor gene-disrupter mice. J Androl 2002; 23: 661-8.
63. Federico G, Favilli T, Cinquanta L, Ughi C, Saggese G. Effect of celiac disease and gluten-free diet on growth hormone-binding protein, insulin-like growth factor-I, and insulin-like growth factor-binding proteins. Horm Res 1997; 48: 108-14.
64. Valdimarsson T, Arnqvist HJ, Toss G, Jarnerot G, Nystrom F, Strom M. Low circulating insulin-like growth factor I in coeliac disease and its relation to bone mineral density. Scand J Gastroenterol 1999; 34: 904-8.
65. Farthing MJ, Edwards CR, Rees LH, Dawson AM. Male gonadal function in coeliac disease. I. Sexual dysfunction, infertility and semen quality. Gut 1982; 23: 608-14.
66. Ludvigsson JF, Ludvigsson J. Coeliac disease in the father affects the newborn. Gut 2001; 49: 169-75.
67. Greco L. The father figure in celiac disease. Gut 2001; 49: 163-6.
68. Green JR, Goble HL, Edwards CR, Dawson AM. Reversible insensitivity to androgens in men with untreated gluten enteropathy. Lancet 1977; 1: 280-2.
69. Farthing MJ, Rees LH, Edwards CR, Dawson AM. Male gonadal function in coeliac disease. II. Sex hormones. Gut 1983; 24: 127-35.
70. Farthing MJ, Mattei AM, Edwards CR, Dawson AM. Relationship between plasma testosterone and dihydrotestosterone concentrations and male facial hair growth. Br J Dermatol 1982; 107: 559-64.
71. Farthing MJ, Rees LH, Dawson AM. Male gonadal function in coeliac disease. III. Pituitary regulation. Clin Endocrinol 1983; 19: 661-71.
72. Reifen R, Buskila D, Maislos M, Lerner A. Serum prolactin in coeliac disease: a marker for disease activity. Arch Dis Child 1997; 77: 155-7.
73. Theintz GE, Nussle D, Cox J, Carmignac D, Duhamel D, Sizonenko PC. Prolactin and the gut: a controversy. J Pediatr Gastroenterol Nutr 1984; 3: 523-8.
74. Varkonyi A, Boda M, Endreffy E, Nemeth I, Timer E. Coeliac disease: always something to discover. Scand J Gastroenterol Suppl 1998; 228: 122-9.
75. Bartke A. Role of growth hormone and prolactin in the control of reproduction: what are we learning from transgenic and knock-out animals? Steroids 1999; 64: 598-604.
76. Marietta F, Black K, Camilleri M, et al. A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice. J Clin Invest 2004; 114: 1090-7.
77. Gawkrodger DJ, Sweeting VM, Edwards CR, Barnetson RS. Male sex hormone status in dermatitis herpetiformis. Br J Dermatol 1985; 112: 57-61.
78. Kinsley CH, Bridges RS. Prenatal stress reduces estradiolinduced prolactin release in male and female rats. Physiol Behav 1987; 40: 647-53.
79. Abraham EJ, Frawley LS. Octylphenol (OP), an environmental estrogen, stimulates prolactin (PRL) gene expression. Life Sci 1997; 60: 1457-65.
80. Neubert D. Vulnerability of the endocrine system to xenobiotic influence. Regul Toxicol Pharmacol 1997; 26 (Part 1): 9-29.
81. Gilberg P, Mallmin H, Petren-Mallmin M, Ljunghall S, Nilsson AG. Two years of treatment with recombinant human growth hormone increases bone mineral density in men with idiopathic osteoporosis. J Clin Endocrinol Metab 2002; 87: 4900-6.
82. Diamond T, Sambrook P, Williamson M, et al. Guidelines for treatment of osteoporosis in men. Aust Fam Physician 2001; 30: 787-91.
83. Kemppainen T, Kroger H, Janatuinen E, et al. Osteoporosis in adult patients with celiac disease. Bone 1999; 24: 249-55.
84. Argente J. Diagnosis of late puberty. Horm Res 1999; 51 (Suppl 3): 95-100.
85. Hancock R, Koren G. Celiac disease during pregnancy. Can Fam Physician 2004; 50: 1361-3.
86. Aslam A, Misbah SA, Talbot K, Chabel H. Vitamin E deficiency induced neurological disease in common variable immunodeficiency: two cases and a review of the literature of vitamin E deficiency. Clin Immunol 2004; 12; 24-9.
87. Dickey W. Low serum vitamin B12 is common in coeliac disease and is not due to autoimmune gastritis. Eur J Gastroenterol Hepatol 2002; 14: 425-7.
88. Hallert C, Grant C, Grehn S, et al. Evidence of poor status in celiac patients on a gluten-free diet for 10 years. Aliment Pharmacol Ther 2002; 16: 1333-9.
89. Reece EA, Homko CJ, Wu YK. Multifactorial basis of the syndrome of diabetic embryopathy. Teratology 1996; 54: 171-82.
90. Stoll C, Dott B, Alembik Y, Koehl C. Congenital anomalies associated with congenital hypothyroidism. Ann Genet 1999; 42: 17-20.
91. Reece EA, Homko CJ, Wu YK, Wiznitzer A. The role of free radicals and membrane lipids in diabetes-induced congenital malformations. J Soc Gynecol Investig 1998; 5: 178-87.
92. Odetti P, Valentini S, Aragno I, et al. Oxidative stress in subjects affected by celiac disease. Free Radic Res 1998; 29: 17-24.
93. Skakkebaek NE, Rajpert-De Meyts E, Jorgensen N, et al. Germ cell cancer and disorders of spermatogenesis: an environmental connection? APMIS 1998; 106: 3-11.
94. Gennari L, Becherini F, Falchetti A, Masi L, Massart F, Brandi ML. Genetics of osteoporosis: role of steroid hormone receptor gene polymorphisms. J Steroid Biochem Mol Biol 2002; 81: 1-24.
95. Abdulkarim AS, Murray JA. Celiac disease. Curr Treat Options Gastroenterol 2002; 5: 27-38.