메뉴 건너뛰기




Volumn 34, Issue 3, 2006, Pages 785-791

Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model

Author keywords

Cardiac arrest; Chlorzoxazone; CYP2E1; Drug metabolism; Hypothermia; Pharmacokinetics

Indexed keywords

CHLORZOXAZONE; CYTOCHROME P450 2E1;

EID: 33644607442     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000201899.52739.4F     Document Type: Article
Times cited : (23)

References (36)
  • 1
    • 2942514479 scopus 로고    scopus 로고
    • Incidence of out-of-hospital cardiac arrest
    • Rea TD, Pearce RM, Raghunathan TE, et al: Incidence of out-of-hospital cardiac arrest. Am J Cardiol 2004; 93:1455-1460
    • (2004) Am J Cardiol , vol.93 , pp. 1455-1460
    • Rea, T.D.1    Pearce, R.M.2    Raghunathan, T.E.3
  • 2
    • 0023811589 scopus 로고
    • Postresuscitation disease
    • Negovsky VA: Postresuscitation disease. Crit Care Med 1988; 16:942-946
    • (1988) Crit Care Med , vol.16 , pp. 942-946
    • Negovsky, V.A.1
  • 3
    • 11144281876 scopus 로고    scopus 로고
    • Mode of death after admission to an intensive care unit following cardiac arrest
    • Laver S, Farrow C, Turner D, et al: Mode of death after admission to an intensive care unit following cardiac arrest. Intensive Care Med 2004; 30:2126-2128
    • (2004) Intensive Care Med , vol.30 , pp. 2126-2128
    • Laver, S.1    Farrow, C.2    Turner, D.3
  • 4
    • 0037148929 scopus 로고    scopus 로고
    • Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia
    • Bernard SA, Gray TW, Buist MD, et al: Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002; 346:557-563
    • (2002) N Engl J Med , vol.346 , pp. 557-563
    • Bernard, S.A.1    Gray, T.W.2    Buist, M.D.3
  • 5
    • 0037148926 scopus 로고    scopus 로고
    • Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest
    • Holzer M, Cerchiari E, Martens P, et al: Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002; 346:549-556
    • (2002) N Engl J Med , vol.346 , pp. 549-556
    • Holzer, M.1    Cerchiari, E.2    Martens, P.3
  • 6
    • 0038204205 scopus 로고    scopus 로고
    • Therapeutic hypothermia after cardiac arrest. An advisory statement by the Advancement Life Support Task Force of the International Liaison Committee on Resuscitation
    • Nolan JP, Morley PT, Hoek TL, et al: Therapeutic hypothermia after cardiac arrest. An advisory statement by the Advancement Life Support Task Force of the International Liaison Committee on Resuscitation. Resuscitation 2003; 57:231-235
    • (2003) Resuscitation , vol.57 , pp. 231-235
    • Nolan, J.P.1    Morley, P.T.2    Hoek, T.L.3
  • 7
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • Bertz RJ, Granneman GR: Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 1997; 32:210-258
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 8
    • 18544401586 scopus 로고    scopus 로고
    • Temperature-dependent pharmacokinetics and pharmacodynamics of vecuronium
    • Caldwell JE, Heier T, Wright PM, et al: Temperature-dependent pharmacokinetics and pharmacodynamics of vecuronium. Anesthesiology 2000; 92:84-93
    • (2000) Anesthesiology , vol.92 , pp. 84-93
    • Caldwell, J.E.1    Heier, T.2    Wright, P.M.3
  • 9
    • 0022257239 scopus 로고
    • Influence of hypothermia on the pharmacokinetics of gentamicin and theophylline in piglets
    • Koren G, Barker C, Bohn D, et al: Influence of hypothermia on the pharmacokinetics of gentamicin and theophylline in piglets. Crit Care Med 1985; 13:844-847
    • (1985) Crit Care Med , vol.13 , pp. 844-847
    • Koren, G.1    Barker, C.2    Bohn, D.3
  • 10
    • 0023269209 scopus 로고
    • The influence of hypothermia on the disposition of fentanyl - Human and animal studies
    • Koren G, Barker C, Goresky G, et al: The influence of hypothermia on the disposition of fentanyl - Human and animal studies. Eur J Clin Pharmacol 1987; 32:373-376
    • (1987) Eur J Clin Pharmacol , vol.32 , pp. 373-376
    • Koren, G.1    Barker, C.2    Goresky, G.3
  • 11
    • 1242292323 scopus 로고    scopus 로고
    • Biphasic concentration change during continuous midazolam administration in brain-injured patients undergoing therapeutic moderate hypothermia
    • Fukuoka N, Aibiki M, Tsukamoto T, et al: Biphasic concentration change during continuous midazolam administration in brain-injured patients undergoing therapeutic moderate hypothermia. Resuscitation 2004; 60:225-230
    • (2004) Resuscitation , vol.60 , pp. 225-230
    • Fukuoka, N.1    Aibiki, M.2    Tsukamoto, T.3
  • 12
    • 0028916450 scopus 로고
    • Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium
    • Leslie K, Sessler DI, Bjorksten AR, et al: Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium. Anesth Analg 1995; 80: 1007-1014
    • (1995) Anesth Analg , vol.80 , pp. 1007-1014
    • Leslie, K.1    Sessler, D.I.2    Bjorksten, A.R.3
  • 13
    • 0035019661 scopus 로고    scopus 로고
    • Effect of mild therapeutic hypothermia on phenytoin pharmacokinetics
    • Iida Y, Nishi S, Asada A: Effect of mild therapeutic hypothermia on phenytoin pharmacokinetics. Ther Drug Monit 2001; 23: 192-197
    • (2001) Ther Drug Monit , vol.23 , pp. 192-197
    • Iida, Y.1    Nishi, S.2    Asada, A.3
  • 14
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: Its physiological and pathological role
    • Lieber CS: Cytochrome P-4502E1: Its physiological and pathological role. Physiol Rev 1997; 77:517-544
    • (1997) Physiol Rev , vol.77 , pp. 517-544
    • Lieber, C.S.1
  • 15
    • 3843099479 scopus 로고    scopus 로고
    • Experimental model of pediatric asphyxial cardiopulmonary arrest in rats
    • Fink EL, Alexander H, Marco CD, et al: Experimental model of pediatric asphyxial cardiopulmonary arrest in rats. Pediatr Crit Care Med 2004; 5:139-144
    • (2004) Pediatr Crit Care Med , vol.5 , pp. 139-144
    • Fink, E.L.1    Alexander, H.2    Marco, C.D.3
  • 16
    • 0032870309 scopus 로고    scopus 로고
    • Effect of the acute-phase response on the pharmacokinetics of chlorzoxazone and cytochrome P-450 2E1 in vitro activity in rats
    • Rockich K, Blouin R: Effect of the acute-phase response on the pharmacokinetics of chlorzoxazone and cytochrome P-450 2E1 in vitro activity in rats. Drug Metab Dispos 1999; 27:1074-1077
    • (1999) Drug Metab Dispos , vol.27 , pp. 1074-1077
    • Rockich, K.1    Blouin, R.2
  • 17
    • 0035733289 scopus 로고    scopus 로고
    • In vitro investigation of the hepatic extraction of RSD1070, a novel antiarrhythmic compound
    • Tong V, Abbott FS, Mbofana S, et al: In vitro investigation of the hepatic extraction of RSD1070, a novel antiarrhythmic compound. J Pharm Pharm Sci 2001; 4:15-23
    • (2001) J Pharm Pharm Sci , vol.4 , pp. 15-23
    • Tong, V.1    Abbott, F.S.2    Mbofana, S.3
  • 18
    • 0029918923 scopus 로고    scopus 로고
    • Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans
    • Bachmann K, Sarver JG: Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans. Pharmacology 1996; 52: 169-177
    • (1996) Pharmacology , vol.52 , pp. 169-177
    • Bachmann, K.1    Sarver, J.G.2
  • 19
    • 0030790808 scopus 로고    scopus 로고
    • Preventable adverse drug events in hospitalized patients: A comparative study of intensive care and general care units
    • Cullen DJ, Sweitzer BJ, Bates DW, et al: Preventable adverse drug events in hospitalized patients: A comparative study of intensive care and general care units. Crit Care Med 1997; 25:1289-1297
    • (1997) Crit Care Med , vol.25 , pp. 1289-1297
    • Cullen, D.J.1    Sweitzer, B.J.2    Bates, D.W.3
  • 20
    • 0034763724 scopus 로고    scopus 로고
    • The pharmacokinetics of remifentanil in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass
    • Michelsen LG, Holford NH, Lu W, et al: The pharmacokinetics of remifentanil in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass. Anesth Analg 2001; 93:1100-1105
    • (2001) Anesth Analg , vol.93 , pp. 1100-1105
    • Michelsen, L.G.1    Holford, N.H.2    Lu, W.3
  • 21
    • 0037387487 scopus 로고    scopus 로고
    • Moderate hypothermia may be detrimental after traumatic brain injury in fentanylanesthetized rats
    • Statler KD, Alexander HL, Vagni VA, et al: Moderate hypothermia may be detrimental after traumatic brain injury in fentanylanesthetized rats. Crit Care Med 2003; 31: 1134-1139
    • (2003) Crit Care Med , vol.31 , pp. 1134-1139
    • Statler, K.D.1    Alexander, H.L.2    Vagni, V.A.3
  • 22
    • 0025879677 scopus 로고
    • Mild intraoperative hypothermia increases duration of action and spontaneous recovery of vecuronium blockade during nitrous oxideisoflurane anesthesia in humans
    • Heier T, Caldwell JE, Sessler DI, et al: Mild intraoperative hypothermia increases duration of action and spontaneous recovery of vecuronium blockade during nitrous oxideisoflurane anesthesia in humans. Anesthesiology 1991; 74:815-819
    • (1991) Anesthesiology , vol.74 , pp. 815-819
    • Heier, T.1    Caldwell, J.E.2    Sessler, D.I.3
  • 23
    • 0033550703 scopus 로고    scopus 로고
    • Opioid neurotoxicity: Fentanyl-induced exacerbation of cerebral ischemia in rats
    • Kofke WA, Garman RH, Garman R, et al: Opioid neurotoxicity: Fentanyl-induced exacerbation of cerebral ischemia in rats. Brain Res 1999; 818:326-334
    • (1999) Brain Res , vol.818 , pp. 326-334
    • Kofke, W.A.1    Garman, R.H.2    Garman, R.3
  • 24
    • 0028223010 scopus 로고
    • Mild intraoperative hypothermia does not change the pharmacodynamics (concentration-effect relationship) of vecuronium in humans
    • Heier T, Caldwell JE, Sharma ML, et al: Mild intraoperative hypothermia does not change the pharmacodynamics (concentration-effect relationship) of vecuronium in humans. Anesth Analg 1994; 78:973-977
    • (1994) Anesth Analg , vol.78 , pp. 973-977
    • Heier, T.1    Caldwell, J.E.2    Sharma, M.L.3
  • 25
    • 0017603437 scopus 로고
    • Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance
    • Pang KS, Rowland M: Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance. J Pharmacokinet Biopharm 1977; 5:625-653
    • (1977) J Pharmacokinet Biopharm , vol.5 , pp. 625-653
    • Pang, K.S.1    Rowland, M.2
  • 26
    • 0017603438 scopus 로고
    • Hepatic clearance of drugs. II. Experimental evidence for acceptance of the "well-stirred" model over the "parallel tube" model using lidocaine in the perfused rat liver in situ preparation
    • Pang KS, Rowland M: Hepatic clearance of drugs. II. Experimental evidence for acceptance of the "well-stirred" model over the "parallel tube" model using lidocaine in the perfused rat liver in situ preparation. J Pharmacokinet Biopharm 1977; 5:655-680
    • (1977) J Pharmacokinet Biopharm , vol.5 , pp. 655-680
    • Pang, K.S.1    Rowland, M.2
  • 27
    • 0017565370 scopus 로고
    • Hepatic clearance of drugs. III. Additional experimental evidence supporting the "well-stirred" model, using metabolite (MEGX) generated from lidocaine under varying hepatic blood flow rates and linear conditions in the perfused rat liver in situ preparation
    • Pang KS, Rowland M: Hepatic clearance of drugs. III. Additional experimental evidence supporting the "well-stirred" model, using metabolite (MEGX) generated from lidocaine under varying hepatic blood flow rates and linear conditions in the perfused rat liver in situ preparation. J Pharmacokinet Biopharm 1977; 5:681-699
    • (1977) J Pharmacokinet Biopharm , vol.5 , pp. 681-699
    • Pang, K.S.1    Rowland, M.2
  • 28
    • 0035165936 scopus 로고    scopus 로고
    • Chlorzoxazone: A probe drug the metabolism of which can be used to monitor one-point blood sampling in the carbon tetrachloride-intoxicated rat
    • Tanaka E: Chlorzoxazone: A probe drug the metabolism of which can be used to monitor one-point blood sampling in the carbon tetrachloride-intoxicated rat. Hum Exp Toxicol 2001; 20:381-385
    • (2001) Hum Exp Toxicol , vol.20 , pp. 381-385
    • Tanaka, E.1
  • 29
    • 0018881294 scopus 로고
    • Effect of hypothermia on drug metabolism. in vitro studies with propranolol and verapamil
    • McAllister RG Jr, Tan TG: Effect of hypothermia on drug metabolism. In vitro studies with propranolol and verapamil. Pharmacology 1980; 20:95-100
    • (1980) Pharmacology , vol.20 , pp. 95-100
    • McAllister Jr., R.G.1    Tan, T.G.2
  • 30
    • 0030799001 scopus 로고    scopus 로고
    • The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data
    • Obach RS, Baxter JG, Liston TE, et al: The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data. J Pharmacol Exp Ther 1997; 283:46-58
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 46-58
    • Obach, R.S.1    Baxter, J.G.2    Liston, T.E.3
  • 31
    • 0032112120 scopus 로고    scopus 로고
    • Interactions between nitric oxide and cytochrome P-450 in the liver
    • Khatsenko O: Interactions between nitric oxide and cytochrome P-450 in the liver. Biochemistry (Mosc) 1998; 63:833-839
    • (1998) Biochemistry (Mosc) , vol.63 , pp. 833-839
    • Khatsenko, O.1
  • 32
    • 0027443904 scopus 로고
    • Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
    • Abdel-Razzak Z, Loyer P, Fautrel A, et al: Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol Pharmacol 1993; 44:707-715
    • (1993) Mol Pharmacol , vol.44 , pp. 707-715
    • Abdel-Razzak, Z.1    Loyer, P.2    Fautrel, A.3
  • 33
    • 0034702826 scopus 로고    scopus 로고
    • Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 6: Advanced cardiovascular life support: Section 8: Postresuscitation care
    • The American Heart Association in collaboration with the International Liaison Committee on Resuscitation.
    • Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 6: Advanced cardiovascular life support: Section 8: Postresuscitation care. The American Heart Association in collaboration with the International Liaison Committee on Resuscitation. Circulation 2000; 102(8 Suppl): I166-I171
    • (2000) Circulation , vol.102 , Issue.8 SUPPL.
  • 34
    • 0037199448 scopus 로고    scopus 로고
    • Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome
    • Adrie C, Adib-Conquy M, Laurent I, et al: Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome. Circulation 2002; 106:562-568
    • (2002) Circulation , vol.106 , pp. 562-568
    • Adrie, C.1    Adib-Conquy, M.2    Laurent, I.3
  • 35
    • 3342969328 scopus 로고    scopus 로고
    • NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle
    • Qi WN, Chaiyakit P, Cai Y, et al: NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle. Microsurgery 2004; 24:316-323
    • (2004) Microsurgery , vol.24 , pp. 316-323
    • Qi, W.N.1    Chaiyakit, P.2    Cai, Y.3
  • 36
    • 0030822729 scopus 로고    scopus 로고
    • Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
    • Tateishi T, Watanabe M, Nakura H, et al: Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits. Anesth Analg 1997; 85: 199-203
    • (1997) Anesth Analg , vol.85 , pp. 199-203
    • Tateishi, T.1    Watanabe, M.2    Nakura, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.