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Volumn 20, Issue 8, 2001, Pages 381-385
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Chlorzoxazone: A probe drug the metabolism of which can be used to monitor one-point blood sampling in the carbon tetrachloride-intoxicated rat
a
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Author keywords
Carbon tetrachloride; Chlorzoxazone; CYP2E1; Hepatic enzyme activity; Liver disease; Rat
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Indexed keywords
ANILINE;
CARBON TETRACHLORIDE;
CHLORZOXAZONE;
CYTOCHROME P450;
CYTOCHROME P450 2E1;
CYTOCHROME P450 INHIBITOR;
DIETHYLDITHIOCARBAMIC ACID;
OLIVE OIL;
UNSPECIFIC MONOOXYGENASE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ARTICLE;
BLOOD SAMPLING;
CONTROLLED STUDY;
CORRELATION FUNCTION;
DRUG BLOOD LEVEL;
DRUG CONCENTRATION;
DRUG ELIMINATION;
DRUG HALF LIFE;
DRUG INTOXICATION;
DRUG METABOLISM;
ENZYME ACTIVITY;
ENZYME KINETICS;
HYDROXYLATION;
IC 50;
IN VITRO STUDY;
IN VIVO STUDY;
LIVER INJURY;
LIVER MICROSOME;
METABOLIC INHIBITION;
MONITORING;
NONHUMAN;
PREDICTION;
PRIORITY JOURNAL;
RAT;
ANILINE HYDROXYLASE;
ANIMALS;
CARBON TETRACHLORIDE;
CHLORZOXAZONE;
CYTOCHROME P-450 CYP2E1;
INHIBITORY CONCENTRATION 50;
INJECTIONS, INTRAPERITONEAL;
LIVER DISEASES;
MALE;
METABOLIC CLEARANCE RATE;
MICROSOMES, LIVER;
MUSCLE RELAXANTS, CENTRAL;
RATS;
RATS, SPRAGUE-DAWLEY;
ANIMALIA;
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EID: 0035165936
PISSN: 09603271
EISSN: None
Source Type: Journal
DOI: 10.1191/096032701682692937 Document Type: Article |
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Times cited : (7)
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References (5)
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