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Volumn 29, Issue 1, 2006, Pages 51-59

Animal models for the study of portal hypertension;Modelos animales en el estudio de la hipertensión portal

Author keywords

[No Author keywords available]

Indexed keywords

EXPERIMENTAL MODEL; LIVER CIRCULATION; LIVER CIRRHOSIS; NONHUMAN; PORTAL HYPERTENSION; PORTAL VEIN BLOOD FLOW; REVIEW; SPLEEN BLOOD FLOW;

EID: 33644556207     PISSN: 02105705     EISSN: None     Source Type: Journal    
DOI: 10.1157/13083254     Document Type: Article
Times cited : (2)

References (82)
  • 1
    • 0020677377 scopus 로고
    • Hyperdynamic circulation in a portal hypertensive rat model: A primary factor for maintenance of chronic portal hypertension
    • Vorobioff J, Bredfeldt J, Groszmann RJ. Hyperdynamic circulation in a portal hypertensive rat model: A primary factor for maintenance of chronic portal hypertension. Am J Physiol. 1983;244:G52-6.
    • (1983) Am J Physiol , vol.244
    • Vorobioff, J.1    Bredfeldt, J.2    Groszmann, R.J.3
  • 2
    • 0021194801 scopus 로고
    • Increased blood flow through the portal system in cirrhotic rats
    • Vorobioff J, Bredfeldt JE, Groszmann RJ. Increased blood flow through the portal system in cirrhotic rats. Gastroenterology. 1984;87:1120-3.
    • (1984) Gastroenterology , vol.87 , pp. 1120-1123
    • Vorobioff, J.1    Bredfeldt, J.E.2    Groszmann, R.J.3
  • 4
    • 0024498240 scopus 로고
    • Problems with animal models of chronic liver disease: Suggestions for improvement in standardization
    • Mullen KD, McCullough AJ. Problems with animal models of chronic liver disease: suggestions for improvement in standardization. Hepatology. 1989;9:500-3.
    • (1989) Hepatology , vol.9 , pp. 500-503
    • Mullen, K.D.1    McCullough, A.J.2
  • 5
    • 0025233652 scopus 로고
    • Splanchnic and systemic hemodynamics in mice using a radioactive microsphere technique
    • Sarin SK, Sabba C, Groszmann RJ. Splanchnic and systemic hemodynamics in mice using a radioactive microsphere technique. Am J Physiol. 1990;258:G365-G9.
    • (1990) Am J Physiol , vol.258
    • Sarin, S.K.1    Sabba, C.2    Groszmann, R.J.3
  • 6
    • 1542347683 scopus 로고    scopus 로고
    • Anti-VEGF receptor-2 monoclonal antibody prevents portal-systemic collateral vessel formation in portal hypertensive mice
    • Fernandez M, Vizzutti F, Garcia-Pagan JC, Rodes J, Bosch J. Anti-VEGF receptor-2 monoclonal antibody prevents portal-systemic collateral vessel formation in portal hypertensive mice. Gastroenterology. 2004;126:886-94.
    • (2004) Gastroenterology , vol.126 , pp. 886-894
    • Fernandez, M.1    Vizzutti, F.2    Garcia-Pagan, J.C.3    Rodes, J.4    Bosch, J.5
  • 8
    • 0021053609 scopus 로고
    • Chronic bile duct ligation in the dog: Hemodynamic characterization of a portal hypertensive model
    • Bosch J, Enriquez R, Groszmann RJ, Storer EH. Chronic bile duct ligation in the dog: hemodynamic characterization of a portal hypertensive model. Hepatology. 1983;3:1002-7.
    • (1983) Hepatology , vol.3 , pp. 1002-1007
    • Bosch, J.1    Enriquez, R.2    Groszmann, R.J.3    Storer, E.H.4
  • 10
    • 0021927396 scopus 로고
    • Increased portal venous resistance hinders portal pressure reduction during the administration of beta-adrenergic blocking agents in a portal hypertensive model
    • Kroeger RJ, Groszmann RJ. Increased portal venous resistance hinders portal pressure reduction during the administration of beta-adrenergic blocking agents in a portal hypertensive model. Hepatology. 1985;5:97-101.
    • (1985) Hepatology , vol.5 , pp. 97-101
    • Kroeger, R.J.1    Groszmann, R.J.2
  • 11
    • 18844475814 scopus 로고
    • Evolution of portal hypertension and mechanisms involved in its maintenance in a rat model
    • Sikuler E, Kravetz D, Groszmann RJ. Evolution of portal hypertension and mechanisms involved in its maintenance in a rat model. Am J Physiol. 1985;248:G618-G25.
    • (1985) Am J Physiol , vol.248
    • Sikuler, E.1    Kravetz, D.2    Groszmann, R.J.3
  • 12
    • 0017227434 scopus 로고
    • Relationship of splanchnic blood flow and portal venous resistance to elevated portal pressure in the dog
    • Witte CL, Tobin GR, Clark DS, Witte MH. Relationship of splanchnic blood flow and portal venous resistance to elevated portal pressure in the dog. Gut. 1976;17:122-6.
    • (1976) Gut , vol.17 , pp. 122-126
    • Witte, C.L.1    Tobin, G.R.2    Clark, D.S.3    Witte, M.H.4
  • 13
    • 0027938229 scopus 로고
    • Hyperdynamic circulation of liver disease 40 years later: Pathophysiology and clinical consequences
    • Groszmann RJ. Hyperdynamic circulation of liver disease 40 years later: pathophysiology and clinical consequences. Hepatology. 1994;20:1359-63.
    • (1994) Hepatology , vol.20 , pp. 1359-1363
    • Groszmann, R.J.1
  • 14
    • 0026557372 scopus 로고
    • Temporal relationship of peripheral vasodilatation, plasma volume expansion and the hyperdynamic circulatory state in portalhypertensive rats
    • Colombato LA, Albillos A, Groszmann RJ. Temporal relationship of peripheral vasodilatation, plasma volume expansion and the hyperdynamic circulatory state in portalhypertensive rats. Hepatology. 1992;15:323-8.
    • (1992) Hepatology , vol.15 , pp. 323-328
    • Colombato, L.A.1    Albillos, A.2    Groszmann, R.J.3
  • 17
    • 1942439080 scopus 로고    scopus 로고
    • Increased brain serotonin turnover correlates with the degree of shunting and hyperammonemia in rats following variable portal vein stenosis
    • Lozeva V, Montgomery JA, Tuomisto L, Rocheleau B, Pannunzio M, Huet PM, et al. Increased brain serotonin turnover correlates with the degree of shunting and hyperammonemia in rats following variable portal vein stenosis. J Hepatol. 2004;40:742-8.
    • (2004) J Hepatol , vol.40 , pp. 742-748
    • Lozeva, V.1    Montgomery, J.A.2    Tuomisto, L.3    Rocheleau, B.4    Pannunzio, M.5    Huet, P.M.6
  • 18
    • 33644525581 scopus 로고    scopus 로고
    • Mild increases in portal pressure upregulate VEGF and eNOS in the intestinal microcirculatory bed leading to vasodilatation and the hyperdynamic circulation
    • Abraldes JG, Iwakiri Y, Loureiro-Silva MR, Haq O, Sessa WC, Groszmann RJ. Mild increases in portal pressure upregulate VEGF and eNOS in the intestinal microcirculatory bed leading to vasodilatation and the hyperdynamic circulation. J Hepatol. 2005;42 Suppl 2:27A.
    • (2005) J Hepatol , vol.42 , Issue.SUPPL. 2
    • Abraldes, J.G.1    Iwakiri, Y.2    Loureiro-Silva, M.R.3    Haq, O.4    Sessa, W.C.5    Groszmann, R.J.6
  • 19
    • 0025810622 scopus 로고
    • Propranolol ameliorates the development of portal-systemic shunting in a chronic murine schistosomiasis model of portal hypertension
    • Sarin SK, Groszmann RJ, Mosca PG, Rojkind M, Stadecker MJ, Bhatnagar R, et al. Propranolol ameliorates the development of portal-systemic shunting in a chronic murine schistosomiasis model of portal hypertension. J Clin Invest. 1991;87:1032-6.
    • (1991) J Clin Invest , vol.87 , pp. 1032-1036
    • Sarin, S.K.1    Groszmann, R.J.2    Mosca, P.G.3    Rojkind, M.4    Stadecker, M.J.5    Bhatnagar, R.6
  • 20
    • 0025855838 scopus 로고
    • Hyperdynamic circulation in a chronic murine schistosomiasis model of portal hypertension
    • Sarin SK, Mosca P, Sabba C, Groszmann RJ. Hyperdynamic circulation in a chronic murine schistosomiasis model of portal hypertension. Hepatology 1991;13:581-4.
    • (1991) Hepatology , vol.13 , pp. 581-584
    • Sarin, S.K.1    Mosca, P.2    Sabba, C.3    Groszmann, R.J.4
  • 21
    • 0025057466 scopus 로고
    • Hemodynamic mechanisms of emerging portal hypertension caused by schistosomiasis in the hamster
    • Morgan JS, Groszmann RJ, Rojkind M, Enriquez R. Hemodynamic mechanisms of emerging portal hypertension caused by schistosomiasis in the hamster. Hepatology. 1990;11:98-104.
    • (1990) Hepatology , vol.11 , pp. 98-104
    • Morgan, J.S.1    Groszmann, R.J.2    Rojkind, M.3    Enriquez, R.4
  • 22
    • 0022457952 scopus 로고
    • Hemodynamic characterization of chronic bile duct-ligated rats: Effect of pentobarbital sodium
    • Lee SS, Girod C, Braillon A, Hadengue A, Lebrec D. Hemodynamic characterization of chronic bile duct-ligated rats: effect of pentobarbital sodium. Am J Physiol. 1986;251:G176-G80.
    • (1986) Am J Physiol , vol.251
    • Lee, S.S.1    Girod, C.2    Braillon, A.3    Hadengue, A.4    Lebrec, D.5
  • 23
    • 0029042638 scopus 로고
    • Role of cirrhosis in the hemodynamic response to hemorrhage in portal hypertension
    • Burns RC, Wu Y, Sitzmann JV. Role of cirrhosis in the hemodynamic response to hemorrhage in portal hypertension. Surgery. 1995;117:488-93.
    • (1995) Surgery , vol.117 , pp. 488-493
    • Burns, R.C.1    Wu, Y.2    Sitzmann, J.V.3
  • 24
    • 4444262044 scopus 로고    scopus 로고
    • Nitric oxide synthase 1 is partly compensating for nitric oxide synthase 3 deficiency in nitric oxide synthase 3 knock-out mice and is elevated in murine and human cirrhosis
    • Biecker E, Neef M, Sagesser H, Shaw S, Koshy A, Reichen J. Nitric oxide synthase 1 is partly compensating for nitric oxide synthase 3 deficiency in nitric oxide synthase 3 knock-out mice and is elevated in murine and human cirrhosis. Liver Int. 2004;24:345-53.
    • (2004) Liver Int , vol.24 , pp. 345-353
    • Biecker, E.1    Neef, M.2    Sagesser, H.3    Shaw, S.4    Koshy, A.5    Reichen, J.6
  • 25
    • 0029078515 scopus 로고
    • Vitamin K1 improves survival in bile-duct-ligated rats with cirrhosis
    • Beck PL, Lee SS. Vitamin K1 improves survival in bile-duct-ligated rats with cirrhosis. J Hepatol. 1995;23:235.
    • (1995) J Hepatol , vol.23 , pp. 235
    • Beck, P.L.1    Lee, S.S.2
  • 26
    • 0035079120 scopus 로고    scopus 로고
    • Effects of blood volume restitution following a portal hypertensive-related bleeding in anesthetized cirrhotic rats
    • Castaneda B, Morales J, Lionetti R, Moitinho E, Andreu V, Perez del Pulgar S, et al. Effects of blood volume restitution following a portal hypertensive-related bleeding in anesthetized cirrhotic rats. Hepatology. 2001;33:821-5.
    • (2001) Hepatology , vol.33 , pp. 821-825
    • Castaneda, B.1    Morales, J.2    Lionetti, R.3    Moitinho, E.4    Andreu, V.5    Perez Del Pulgar, S.6
  • 27
    • 0034120477 scopus 로고    scopus 로고
    • An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis
    • Cho JJ, Hocher B, Herbst H, Jia JD, Ruehl M, Hahn EG, et al. An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology. 2000;118:1169-78.
    • (2000) Gastroenterology , vol.118 , pp. 1169-1178
    • Cho, J.J.1    Hocher, B.2    Herbst, H.3    Jia, J.D.4    Ruehl, M.5    Hahn, E.G.6
  • 28
    • 0027466157 scopus 로고
    • A model of cholestasis in the rat, using a microsurgical technique
    • Aller MA, Lorente L, Alonso S, Arias J. A model of cholestasis in the rat, using a microsurgical technique. Scand J Gastroenterol. 1993;28:10-4.
    • (1993) Scand J Gastroenterol , vol.28 , pp. 10-14
    • Aller, M.A.1    Lorente, L.2    Alonso, S.3    Arias, J.4
  • 30
    • 0021238490 scopus 로고
    • Prolonged bile duct obstruction: A new experimental model for cirrhosis in the rat
    • Kountouras J, Billing BH, Scheuer PJ. Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat. Br J Exp Pathol. 1984;65:305-11.
    • (1984) Br J Exp Pathol , vol.65 , pp. 305-311
    • Kountouras, J.1    Billing, B.H.2    Scheuer, P.J.3
  • 31
    • 0018679769 scopus 로고
    • Portal hypertension after bile duct obstruction: Effect of bile diversion on portal pressure in the rat
    • Franco D, Gigou M, Szekely AM, Bismuth H. Portal hypertension after bile duct obstruction: effect of bile diversion on portal pressure in the rat. Arch Surg. 1979;114:1064-7.
    • (1979) Arch Surg , vol.114 , pp. 1064-1067
    • Franco, D.1    Gigou, M.2    Szekely, A.M.3    Bismuth, H.4
  • 33
    • 0026030644 scopus 로고
    • Hemodynamic characterization of conscious and ketamine-anesthetized bile duct-ligated rats
    • Sikuler E, Buchs AE, Yaari A, Keynan A. Hemodynamic characterization of conscious and ketamine-anesthetized bile duct-ligated rats. Am J Physiol. 1991;260:G161-G6.
    • (1991) Am J Physiol , vol.260
    • Sikuler, E.1    Buchs, A.E.2    Yaari, A.3    Keynan, A.4
  • 34
    • 0026512122 scopus 로고
    • Carbon tetrachloride induced cirrhosis in rats: A useful tool for investigating the pathogenesis of ascites in chronic liver disease
    • Jimenez W, Claria J, Arroyo V, Rodes J. Carbon tetrachloride induced cirrhosis in rats: a useful tool for investigating the pathogenesis of ascites in chronic liver disease. J Gastroenterol Hepatol. 1992;7:90-7.
    • (1992) J Gastroenterol Hepatol , vol.7 , pp. 90-97
    • Jimenez, W.1    Claria, J.2    Arroyo, V.3    Rodes, J.4
  • 35
    • 0000476854 scopus 로고    scopus 로고
    • Renal dysfunction and ascites in carbon-tetrachloride-induced cirrhosis in rats
    • Arrovo V, Gines P, Rodes J, Schrier RW, editors. Maiden, MA: Blackwell Science
    • Claria J, Jimenez W. Renal dysfunction and ascites in carbon-tetrachloride-induced cirrhosis in rats. En: Arrovo V, Gines P, Rodes J, Schrier RW, editors. Ascites and renal dysfunction in liver disease. Maiden, MA: Blackwell Science; 1999. p. 379-98.
    • (1999) Ascites and Renal Dysfunction in Liver Disease , pp. 379-398
    • Claria, J.1    Jimenez, W.2
  • 36
    • 0036163806 scopus 로고    scopus 로고
    • 5-Lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: A possible role of cysteinyl-leukotrienes
    • Graupera M, Garcia-Pagan JC, Titos E, Claria J, Massaguer A, Bosch J, et al. 5-lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes. Gastroenterology. 2002;122:387-93.
    • (2002) Gastroenterology , vol.122 , pp. 387-393
    • Graupera, M.1    Garcia-Pagan, J.C.2    Titos, E.3    Claria, J.4    Massaguer, A.5    Bosch, J.6
  • 37
    • 10744228583 scopus 로고    scopus 로고
    • Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
    • Kamada Y, Tamura S, Kiso S, Matsumoto H, Saji Y, Yoshida Y, et al. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology. 2003;125:1796-807.
    • (2003) Gastroenterology , vol.125 , pp. 1796-1807
    • Kamada, Y.1    Tamura, S.2    Kiso, S.3    Matsumoto, H.4    Saji, Y.5    Yoshida, Y.6
  • 38
    • 0020470177 scopus 로고
    • High yield micronodular cirrhosis in the rat
    • Proctor E, Chatamra K. High yield micronodular cirrhosis in the rat. Gastroenterology. 1982;83:1183-90.
    • (1982) Gastroenterology , vol.83 , pp. 1183-1190
    • Proctor, E.1    Chatamra, K.2
  • 40
    • 0034813705 scopus 로고    scopus 로고
    • Adenosine reverses a preestablished CC14-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats
    • Hernandez-Munoz R, Az-Munoz M, Suarez-Cuenca JA, Trejo-Solis C, Lopez V, Sanchez-Sevilla L, et al. Adenosine reverses a preestablished CC14-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats. Hepatology. 2001;34:677-87.
    • (2001) Hepatology , vol.34 , pp. 677-687
    • Hernandez-Munoz, R.1    Az-Munoz, M.2    Suarez-Cuenca, J.A.3    Trejo-Solis, C.4    Lopez, V.5    Sanchez-Sevilla, L.6
  • 41
    • 33644541756 scopus 로고
    • Cirrosis hepática experimental producida por tetracloruro de carbono: Técnicas utilizadas y características histológicas, hemodinámicas y hormonales
    • Jimenez W. Cirrosis hepática experimental producida por tetracloruro de carbono: técnicas utilizadas y características histológicas, hemodinámicas y hormonales. Gastroenterol Hepatol. 1988;11:531-8.
    • (1988) Gastroenterol Hepatol , vol.11 , pp. 531-538
    • Jimenez, W.1
  • 42
    • 0345118191 scopus 로고    scopus 로고
    • Déficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas
    • Loureiro-Silva MR, Cadelina GW, Groszmann RJ. Déficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas. Am J Physiol Gastrointest Liver Physiol. 2003;284:G567-G74.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Loureiro-Silva, M.R.1    Cadelina, G.W.2    Groszmann, R.J.3
  • 43
    • 0036105275 scopus 로고    scopus 로고
    • Reproducible production of thioacetamide-induced macronodular cirrhosis in the rat with no mortality
    • Li X, Benjamin IS, Alexander B. Reproducible production of thioacetamide-induced macronodular cirrhosis in the rat with no mortality. J Hepatol. 2002;36:488-93.
    • (2002) J Hepatol , vol.36 , pp. 488-493
    • Li, X.1    Benjamin, I.S.2    Alexander, B.3
  • 44
    • 11144269045 scopus 로고    scopus 로고
    • Overexpression of thioredoxin pre-events thioacetamide-induced hepatic fibrosis in mice
    • Okuyama H, Nakamura H, Shimahara Y, Uyama N, Kwon YW, Kawada N, et al. Overexpression of thioredoxin pre-events thioacetamide-induced hepatic fibrosis in mice. J Hepatol. 2005;42:117-23.
    • (2005) J Hepatol , vol.42 , pp. 117-123
    • Okuyama, H.1    Nakamura, H.2    Shimahara, Y.3    Uyama, N.4    Kwon, Y.W.5    Kawada, N.6
  • 45
    • 1642539139 scopus 로고    scopus 로고
    • ET-1 and TNF-alpha in HPS: Analysis in prehepatic portal hypertension and biliary and nonbiliary cirrhosis in rats
    • Luo B, Liu L, Tang L, Zhang J, Ling Y, Fallon MB. ET-1 and TNF-alpha in HPS: analysis in prehepatic portal hypertension and biliary and nonbiliary cirrhosis in rats. Am J Physiol Gastrointest Liver Physiol. 2004;286:G294-G303.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286
    • Luo, B.1    Liu, L.2    Tang, L.3    Zhang, J.4    Ling, Y.5    Fallon, M.B.6
  • 46
  • 48
    • 0034009735 scopus 로고    scopus 로고
    • Spleno-renal shunt blood flow is an accurate index of collateral circulation in different models of portal hypertension and after pharmacological changes in rats
    • Veal N, Oberti F, Moal F, Vuillemin E, Fort J, Kaassis M, et al. Spleno-renal shunt blood flow is an accurate index of collateral circulation in different models of portal hypertension and after pharmacological changes in rats. J Hepatol. 2000;32:434-40.
    • (2000) J Hepatol , vol.32 , pp. 434-440
    • Veal, N.1    Oberti, F.2    Moal, F.3    Vuillemin, E.4    Fort, J.5    Kaassis, M.6
  • 49
    • 4344617997 scopus 로고    scopus 로고
    • Animal models of nonalcoholic fatty liver disease and steatohepatitis
    • Nanji AA. Animal models of nonalcoholic fatty liver disease and steatohepatitis. Clin Liver Dis. 2004;8:559-74, ix.
    • (2004) Clin Liver Dis , vol.8 , pp. 559-574
    • Nanji, A.A.1
  • 50
  • 52
    • 0026533719 scopus 로고
    • Treatment of Budd-Chiari syndrome due to inferior vena cava occlusion by combined portal and vena caval decompression
    • Orloff MJ, Daily PO, Girard B. Treatment of Budd-Chiari syndrome due to inferior vena cava occlusion by combined portal and vena caval decompression. Am J Surg. 1992;163:137-42.
    • (1992) Am J Surg , vol.163 , pp. 137-142
    • Orloff, M.J.1    Daily, P.O.2    Girard, B.3
  • 53
    • 0021816284 scopus 로고
    • Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators
    • Bhathal PS, Grossman HJ. Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators. J Hepatol. 1985;1:325-37.
    • (1985) J Hepatol , vol.1 , pp. 325-337
    • Bhathal, P.S.1    Grossman, H.J.2
  • 55
    • 0141451840 scopus 로고    scopus 로고
    • Cyclooxygenase-1 inhibition corrects endothelial dysfunction in cirrhotic rat livers
    • Graupera M, Garcia-Pagan JC, Pares M, Abraldes JG, Rosello J, et al. Cyclooxygenase-1 inhibition corrects endothelial dysfunction in cirrhotic rat livers. J Hepatol. 2003;39:515-21.
    • (2003) J Hepatol , vol.39 , pp. 515-521
    • Graupera, M.1    Garcia-Pagan, J.C.2    Pares, M.3    Abraldes, J.G.4    Rosello, J.5
  • 56
    • 0036321638 scopus 로고    scopus 로고
    • Bioactivation of nitroglycerin and vasomotor response to nitric oxide are impaired in cirrhotic rat livers
    • Dudenhoefer AA, Loureiro-Silva MR, Cadelina GW, Gupta T, Groszmann RJ. Bioactivation of nitroglycerin and vasomotor response to nitric oxide are impaired in cirrhotic rat livers. Hepatology. 2002;36:381-5.
    • (2002) Hepatology , vol.36 , pp. 381-385
    • Dudenhoefer, A.A.1    Loureiro-Silva, M.R.2    Cadelina, G.W.3    Gupta, T.4    Groszmann, R.J.5
  • 57
    • 0031682956 scopus 로고    scopus 로고
    • Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats
    • Gupta TK, Toruner M, Chung MK, Groszmann RJ. Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats. Hepatology. 1998;28:926-31.
    • (1998) Hepatology , vol.28 , pp. 926-931
    • Gupta, T.K.1    Toruner, M.2    Chung, M.K.3    Groszmann, R.J.4
  • 59
    • 0032811405 scopus 로고    scopus 로고
    • Endothelin-1 modulates intrahepatic resistance in a rat model of noncirrhotic portal hypertension
    • Kamath PS, Tyce GM, Miller VM, Edwards BS, Rorie DK. Endothelin-1 modulates intrahepatic resistance in a rat model of noncirrhotic portal hypertension. Hepatology. 1999;30:401-7.
    • (1999) Hepatology , vol.30 , pp. 401-407
    • Kamath, P.S.1    Tyce, G.M.2    Miller, V.M.3    Edwards, B.S.4    Rorie, D.K.5
  • 60
    • 0029742225 scopus 로고    scopus 로고
    • Population of hepatic macrophages and response of perfused liver to platelet-activating factor during production of thioacetamide-induced cirrhosis in rats
    • Noda S, Masumi S, Moriyama M, Kannan Y, Ohta M, Sugano T, et al. Population of hepatic macrophages and response of perfused liver to platelet-activating factor during production of thioacetamide-induced cirrhosis in rats. Hepatology. 1996;24:412-8.
    • (1996) Hepatology , vol.24 , pp. 412-418
    • Noda, S.1    Masumi, S.2    Moriyama, M.3    Kannan, Y.4    Ohta, M.5    Sugano, T.6
  • 61
    • 0027745949 scopus 로고
    • Hemodynamic characterization in experimental liver cirrhosis induced by thioacetamide administration
    • Hori N, Okanoue T, Sawa Y, Mori T, Kashima K. Hemodynamic characterization in experimental liver cirrhosis induced by thioacetamide administration. Dig Dis Sci. 1993;38:2195-202.
    • (1993) Dig Dis Sci , vol.38 , pp. 2195-2202
    • Hori, N.1    Okanoue, T.2    Sawa, Y.3    Mori, T.4    Kashima, K.5
  • 62
    • 0014301215 scopus 로고
    • Vascular responses in mesenteric arteries from genetic and renal hypertensive rats
    • McGregor DD, Smirk FH. Vascular responses in mesenteric arteries from genetic and renal hypertensive rats. Am J Physiol. 1968;214:1429-33.
    • (1968) Am J Physiol , vol.214 , pp. 1429-1433
    • McGregor, D.D.1    Smirk, F.H.2
  • 63
    • 0029985846 scopus 로고    scopus 로고
    • Hyporeactivity of mesenteric resistance arteries in portal hypertensive rats
    • Sogni P, Sabry S, Moreau R, Gadano A, Lebrec D, Nh-Xuan AT. Hyporeactivity of mesenteric resistance arteries in portal hypertensive rats. J Hepatol. 1996;24:487-90.
    • (1996) J Hepatol , vol.24 , pp. 487-490
    • Sogni, P.1    Sabry, S.2    Moreau, R.3    Gadano, A.4    Lebrec, D.5    Nh-Xuan, A.T.6
  • 64
    • 0025847372 scopus 로고
    • Intestinal microvascular responsiveness to norepinephrine in chronic portal hypertension
    • Joh T, Granger DN, Benoit JN. Intestinal microvascular responsiveness to norepinephrine in chronic portal hypertension. Am J Physiol. 1991;260:H1135-H43.
    • (1991) Am J Physiol , vol.260
    • Joh, T.1    Granger, D.N.2    Benoit, J.N.3
  • 65
    • 0026708176 scopus 로고
    • In vitro hyporeactivity to methoxamine in portal hypertensive rats: Reversal by nitric oxide blockade
    • Sieber CC, Groszmann RJ. In vitro hyporeactivity to methoxamine in portal hypertensive rats: reversal by nitric oxide blockade. Am J Physiol. 1992;262:G996-1001.
    • (1992) Am J Physiol , vol.262
    • Sieber, C.C.1    Groszmann, R.J.2
  • 66
    • 0027236198 scopus 로고
    • Role of nitric oxide in the in vitro splanchnic vascular hyporeactivity in ascitic cirrhotic rats
    • Sieber CC, Lopez-Talavera JC, Groszmann RJ. Role of nitric oxide in the in vitro splanchnic vascular hyporeactivity in ascitic cirrhotic rats. Gastroenterology. 1993;104:1750-4.
    • (1993) Gastroenterology , vol.104 , pp. 1750-1754
    • Sieber, C.C.1    Lopez-Talavera, J.C.2    Groszmann, R.J.3
  • 67
    • 0019522762 scopus 로고
    • Measurement of portal-systemic shunting in the rat by using gamma-labeled microspheres
    • Chojkier M, Groszmann RJ. Measurement of portal-systemic shunting in the rat by using gamma-labeled microspheres. Am J Physiol. 1981;240:G371-5.
    • (1981) Am J Physiol , vol.240
    • Chojkier, M.1    Groszmann, R.J.2
  • 68
    • 0037621928 scopus 로고    scopus 로고
    • The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: Studies in gene-knockout mice
    • Theodorakis NG, Wang YN, Skill NJ, Metz MA, Cahill PA, Redmond EM, et al. The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice. Gastroenterology. 2003;124:1500-8.
    • (2003) Gastroenterology , vol.124 , pp. 1500-1508
    • Theodorakis, N.G.1    Wang, Y.N.2    Skill, N.J.3    Metz, M.A.4    Cahill, P.A.5    Redmond, E.M.6
  • 69
    • 0026806784 scopus 로고
    • Pharmacology of portal-systemic collaterals in portal hypertensive rats: Role of endothelium
    • Mosca P, Lee FY, Kaumann AJ, Groszmann RJ. Pharmacology of portal-systemic collaterals in portal hypertensive rats: role of endothelium. Am J Physiol. 1992;263:G544-G50.
    • (1992) Am J Physiol , vol.263
    • Mosca, P.1    Lee, F.Y.2    Kaumann, A.J.3    Groszmann, R.J.4
  • 70
    • 0027946525 scopus 로고
    • Increased nitric oxide-dependent vasorelaxation in aortic rings of cirrhotic rats with ascites
    • Claria J, Jimenez W, Ros J, Rigol M, Angeli P, Arroyo V, et al. Increased nitric oxide-dependent vasorelaxation in aortic rings of cirrhotic rats with ascites [see comments]. Hepatology. 1994;20:1615-21.
    • (1994) Hepatology , vol.20 , pp. 1615-1621
    • Claria, J.1    Jimenez, W.2    Ros, J.3    Rigol, M.4    Angeli, P.5    Arroyo, V.6
  • 71
    • 0026518464 scopus 로고
    • Pathogenesis of arterial hypotension in cirrhotic rats with ascites: Role of endogenous nitric oxide
    • Claria J, Jimenez W, Ros J, Asbert M, Castro A, Arroyo V, et al. Pathogenesis of arterial hypotension in cirrhotic rats with ascites: role of endogenous nitric oxide. Hepatology. 1992;15:343-9.
    • (1992) Hepatology , vol.15 , pp. 343-349
    • Claria, J.1    Jimenez, W.2    Ros, J.3    Asbert, M.4    Castro, A.5    Arroyo, V.6
  • 72
    • 0029080711 scopus 로고
    • Role of nitric oxide and prostacyclin in the control of renal perfusion in experimental cirrhosis
    • Ros J, Claria J, Jimenez W, Bosch-Marce M, Angeli P, Arroyo V, et al. Role of nitric oxide and prostacyclin in the control of renal perfusion in experimental cirrhosis. Hepatology. 1995;22:915-20.
    • (1995) Hepatology , vol.22 , pp. 915-920
    • Ros, J.1    Claria, J.2    Jimenez, W.3    Bosch-Marce, M.4    Angeli, P.5    Arroyo, V.6
  • 73
    • 0026583936 scopus 로고
    • Vasodilatation and sodium retention in prehepatic portal hypertension
    • Albillos A, Colombato LA, Groszmann RJ. Vasodilatation and sodium retention in prehepatic portal hypertension [see comments]. Gastroenterology. 1992;102:931-5.
    • (1992) Gastroenterology , vol.102 , pp. 931-935
    • Albillos, A.1    Colombato, L.A.2    Groszmann, R.J.3
  • 74
    • 0030044539 scopus 로고    scopus 로고
    • The role of central blood volume in the development of sodium retention in portal hypertensive rats
    • Colombato LA, Albillos A, Groszmann RJ. The role of central blood volume in the development of sodium retention in portal hypertensive rats. Gastroenterology. 1996;110:193-8.
    • (1996) Gastroenterology , vol.110 , pp. 193-198
    • Colombato, L.A.1    Albillos, A.2    Groszmann, R.J.3
  • 75
    • 0023749667 scopus 로고
    • Peripheral arterial vasodilation hypothesis: A proposal for the initiation of renal sodium and water retention in cirrhosis
    • Schrier RW, Arroyo V, Bernardi M, Epstein M, Henriksen JH, Rodes J. Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis. Hepatology. 1988;8:1151-7.
    • (1988) Hepatology , vol.8 , pp. 1151-1157
    • Schrier, R.W.1    Arroyo, V.2    Bernardi, M.3    Epstein, M.4    Henriksen, J.H.5    Rodes, J.6
  • 77
    • 0021964592 scopus 로고
    • Temporal relationship between hyperaldosteronism, sodium retention and ascites formation in rats with experimental cirrhosis
    • Jimenez W, Martinez-Pardo A, Arroyo V, Bruix J, Rimola A, Gaya J, et al. Temporal relationship between hyperaldosteronism, sodium retention and ascites formation in rats with experimental cirrhosis. Hepatology. 1985;5:245-50.
    • (1985) Hepatology , vol.5 , pp. 245-250
    • Jimenez, W.1    Martinez-Pardo, A.2    Arroyo, V.3    Bruix, J.4    Rimola, A.5    Gaya, J.6
  • 78
    • 0025905563 scopus 로고
    • Temporal relationship between the decrease in arterial pressure and sodium retention in conscious spontaneously hypertensive rats with carbon tetrachloride-induced cirrhosis
    • Lopez C, Jimenez W, Arroyo V, Claria J, La Villa G, Asbert M, et al. Temporal relationship between the decrease in arterial pressure and sodium retention in conscious spontaneously hypertensive rats with carbon tetrachloride-induced cirrhosis. Hepatology. 1991;13:585-9.
    • (1991) Hepatology , vol.13 , pp. 585-589
    • Lopez, C.1    Jimenez, W.2    Arroyo, V.3    Claria, J.4    La Villa, G.5    Asbert, M.6
  • 79
    • 0026689555 scopus 로고
    • Effects of acute normovolemic anemia on gastric mucosal blood flow in rats: Role of nitric oxide
    • Panes J, Casadevall M, Pique JM, Bosch J, Whittle BJ, Teres J. Effects of acute normovolemic anemia on gastric mucosal blood flow in rats: role of nitric oxide. Gastroenterology. 1992;103:407-13.
    • (1992) Gastroenterology , vol.103 , pp. 407-413
    • Panes, J.1    Casadevall, M.2    Pique, J.M.3    Bosch, J.4    Whittle, B.J.5    Teres, J.6
  • 80
    • 0027993228 scopus 로고
    • Gastric microcirculatory changes of portal-hypertensive rats can be attenuated by long-term estrogen-progestagen treatment
    • Panes J, Casadevall M, Fernandez M, Pique JM, Bosch J, Casamitjana R, et al. Gastric microcirculatory changes of portal-hypertensive rats can be attenuated by long-term estrogen-progestagen treatment. Hepatology. 1994;20:1261-70.
    • (1994) Hepatology , vol.20 , pp. 1261-1270
    • Panes, J.1    Casadevall, M.2    Fernandez, M.3    Pique, J.M.4    Bosch, J.5    Casamitjana, R.6
  • 81
    • 0030925966 scopus 로고    scopus 로고
    • Common bile duct ligation in the rat: A model of intrapulmonary vasodilatation and hepatopulmonary syndrome
    • Fallon MB, Abrams GA, McGrath JW, Hou Z, Luo B. Common bile duct ligation in the rat: a model of intrapulmonary vasodilatation and hepatopulmonary syndrome. Am J Physiol. 1997;272:G779-G84.
    • (1997) Am J Physiol , vol.272
    • Fallon, M.B.1    Abrams, G.A.2    McGrath, J.W.3    Hou, Z.4    Luo, B.5
  • 82
    • 0345017778 scopus 로고    scopus 로고
    • Effects of the Via vasopressin agonist F-180 on portal hypertension-related bleeding in portal hypertensive rats
    • Morales J, Moitinho E, Abraldes JG, Fernandez M, Bosch J. Effects of the Via vasopressin agonist F-180 on portal hypertension-related bleeding in portal hypertensive rats. Hepatology. 2003;38:1378-83
    • (2003) Hepatology , vol.38 , pp. 1378-1383
    • Morales, J.1    Moitinho, E.2    Abraldes, J.G.3    Fernandez, M.4    Bosch, J.5


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