Metabolic rate determines haematopoietic stem cell self-renewal

Medical Hypotheses

Volumn 63, Issue 3, 2004, Pages 476-480

  Sastry, P S R K ^a  

^a JASLOK HOSPITAL AND RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

WNT PROTEIN;

ALLOMETRY; CELL COUNT; CELL DIVISION; CELL LINEAGE; EXTRAMEDULLARY HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HYPOTHESIS; METABOLIC RATE; PREDICTION; PRIORITY JOURNAL; REVIEW; STOCHASTIC MODEL; TELOMERE;

ANIMALIA;

EID: 3343002085     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.02.048     Document Type: Article

References (20)

1. Abkowitz J.L., Catlin S.N., McCallie M.T., et al. Evidence that the number of haematopoietic stem cells per animal is conserved in mammals. Blood. 100:2002;2665-2667
2. McCarthy K.F. Marrow frequency of rat long-term repopulating cells: evidence that haematopoietic stem cell concentration may be inversely proportional to species body weight. Blood. 101(9):2003;3431-3435
3. Gordon M.Y., Lewis J.L., Marley S.B. Of mice and men... and elephants. Blood. 100(13):2002;4679-4680
4. Enver T., Heyworth C.M., Dexter T.M. Do stem cells play dice? Blood. 92:1998;348-351
5. Socolovsky M., Lodish H.F., Daley G.Q. Control of haematopoietic differentiation; Lack of specificity in signaling by cytokine receptors. Proc. Natl. Acad. Sci. USA. 95:1998;6573-6575
6. Metcalf D. Lineage commitment and maturation in hematopoietic cells; the case for extrinsic regulation. Blood. 1998;345-347
7. Theise N.D., Krause D.S. Suggestions for a new paradigm of cell differentiative potential. Blood Cell Mol. Dis. 27:2001;625-631
8. Theise N.D., Krause D.S. Toward a new paradigm of cell plasticity. Leukemia. 16(4):2002;542-548
9. Quesenberry P.J., Colvin G.A., Lambert J.F. The chiaroscuro stem cell: a unified stem cell theory. Blood. 100(13):2002;4266-4271
10. West G.B., Woodruff W.H., Brown J.H. Allometric scaling of metabolic rate from molecules and mitochondria to cells and mammals. Proc. Natl. Acad. Sci. USA. 99(Suppl 1):2002;2473-2478
11. Singer M.A. Of mice and men and elephants: metabolic rate sets glomerular filtration rate. Am. J. Kidney Dis. 37(1):2001;164-178
12. Reya T., Duncan A.W., Ailles L., Domen J., Scherer D.C., Willert K., Hintz L., Nusse R., Weissman I.L. A role for Wnt signaling in self-renewal of haematopoietic stem cells. Nature. 423(6938):2003;409-414
13. Wang H.Y., Malbon C.C. Wnt signaling, Ca2+ and cyclic GMP; visualizing frizzled functions. Science. 300(5625):2003;1529-1530
14. Yamaoka T., Yano M., Kondo M., et al. Feedback inhibition of amidophosphoribosyltransferase regulates the rate of cell growth via purine nucleotide, DNA, and protein syntheses. J. Biol. Chem. 276(24):2001;21285-21291
15. Nisoli E., Clementi E., Paolucci C. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science. 299(5608):2003;896-899
16. Allsopp R.C., Cheshier S., Weissman I.L. Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic cells. J. Exp. Med. 193(8):2001;917-924
17. Notaro R., Cimmino A., Tabarini D., Rotoli B., Luzzatto L. In vivo telomere dynamics of human hematopoietic stem cells. Proc. Natl. Acad. Sci. 94:1997;13782-13785
18. Mathioudakis G., Storb R., McSweeney P.A., Torok-Storb B., Lansdorp P.M., Brummendorf T.H., Gass M.J., Bryant E.M., Storek J., Flowers M.E.D., Gooley T., Nash R.A. Polyclonal hematopoiesis with variable telomere shortening in human long-term allogeneic marrow graft recipients. Blood. 96:2000;3991-3994
19. de Pauw E.S., Otto S.A., Wijnen J.T., Vossen J.M., van Weel M.H., Tanke H.J., Miedema F., Willemze R., Roelofs H., Fibbe W.E. Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion. Br. J. Haematol. 116(2):2002;491-496
20. Roelofs H., de Pauw E.S., Zwinderman A.H., Opdam S.M., Willemze R., Tanke H.J., Fibbe W.E. Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation. Blood. 101(1):2003;358-362