A novel protein expression strategy using recombinant bovine respiratory syncytial virus (BRSV): Modifications of the peptide sequence between the two furin cleavage sites of the BRSV fusion protein yield secreted proteins, but affect processing and function of the BSRV fusion protein

Journal of General Virology

Volumn 85, Issue 7, 2004, Pages 1815-1824

  König, Patricia ^a   Giesow, Katrin ^a   Schuldt, Kathrin ^a   Buchholz, Ursula J ^a,b   Keil, Günther M ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISULFIDE; FURIN; GAMMA INTERFERON; GLYCOPROTEIN; HYBRID PROTEIN; INTERLEUKIN 2; INTERLEUKIN 4; PROTEIN SUBUNIT; RESPIRATORY SYNCYTIAL VIRUS VACCINE; VIRUS FUSION PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; GENE MUTATION; INTRACELLULAR TRANSPORT; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SECRETION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SYNCYTIUM; TARGET CELL; VIRION; VIROGENESIS; ANIMAL; CATTLE; CELL LINE; CHEMISTRY; GENETIC TRANSCRIPTION; GENETICS; KIDNEY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

BOVINAE; BOVINE RESPIRATORY SYNCYTIAL VIRUS; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATTLE; CELL LINE; FURIN; KIDNEY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RESPIRATORY SYNCYTIAL VIRUS, BOVINE; TRANSCRIPTION, GENETIC; VIRAL FUSION PROTEINS;

EID: 3342986723     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.80010-0     Document Type: Article

References (18)

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