Nitric oxide and endothelial cell aging

European Journal of Clinical Pharmacology

Volumn 62, Issue 1, 2006, Pages 137-140

  Haendeler, Judith ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Endothelial cells; Nitric oxide bioavailability; Thioredoxin

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TELOMERASE; THIOREDOXIN; ACETYLCYSTEINE;

APOPTOSIS; BIOAVAILABILITY; BLOOD FLOW; BLOOD PRESSURE REGULATION; CELL AGING; CONFERENCE PAPER; CORRELATION ANALYSIS; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; LAMINAR FLOW; NITROSYLATION; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; SHEAR STRESS; SIGNAL TRANSDUCTION; AGING; BLOOD VESSEL; OXIDATION REDUCTION REACTION;

EID: 33344468578     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-005-0008-8     Document Type: Conference Paper

References (42)

1. Ross R (1995) Cell biology of atherosclerosis. Annu Rev Physiol 57:791-804
2. Hoffmann J, Haendeler J, Aicher A, Rossig L, Vasa M, Zeiher AM, Dimmeler S (2001) Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide. Circ Res 89:709-715
3. Miyashiro JK, Poppa V, Berk BC (1997) Flow-induced vascular remodeling in the rat carotid artery diminishes with age. Circ Res 81:311-319
4. Harrison DG (1994) Endothelial dysfunction in atherosclerosis. Basic Res Cardiol 1:87-102
5. Dimmeler S, Zeiher AM (1999) Nitric oxide - an endothelial cell survival factor. Cell Death Differ 6:964-968
6. Murohara T, Witzenbichler B, Spyridopoulos I, Asahara T, Ding B, Sullivan A, Losordo DW, Isner JM (1999) Role of endothelial nitric oxide synthase in endothelial cell migration. Arterioscler Thromb Vasc Biol 19:1156-1161
7. Tsao PS, Cooke JP (1998) Endothelial alterations in hypercholesterolemia: more than simply vasodilator dysfunction. J Cardiovasc Pharmacol 32(Suppl 3):S48-S53
8. Nathan C, Xie QW (1994) Regulation of biosynthesis of nitric oxide. J Biol Chem 269:13725-13728
9. Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC (1995) Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377:239-242
10. Murohara T, Asahara T, Silver M, Bauters C, Masuda H, Kalka C, Kearney M, Chen D, Symes JF, Fishman MC, Huang PL, Isner JM (1998) Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest 101:2567-2578
11. Moroi M, Zhang L, Yasuda T, Virmani R, Gold HK, Fishman MC, Huang PL (1998) Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular responses to injury in mice. J Clin Invest 101:1225-1232
12. Schachinger V, Britten MB, Zeiher AM (2000) Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 101:1899-1906
13. Fujita N, Manabe H, Yoshida N, Matsumoto N, Ochiai J, Masui Y, Uemura M, Naito Y, Yoshikawa T (2000) Inhibition of angiotensin-converting enzyme protects endothelial cell against hypoxia/reoxygenation injury. Biofactors 11:257-266
14. Dimmeler S, Rippmann V, Weiland U, Haendeler J, Zeiher AM (1997) Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ Res 81:970-976
15. Kontush A, Chancharme L, Escargueil-Blanc I, Therond P, Salvayre R, Negre-Salvayre A, Chapman MJ (2003) Mildly oxidized LDL particle subspecies are distinct in their capacity to induce apoptosis in endothelial cells: role of lipid hydroperoxides. FASEB J 17:88-90
16. Dimmeler S, Haendeler J, Galle J, Zeiher AM (1997) Oxidized low density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases: a mechanistic clue to the response to injury hypothesis. Circulation 95:1760-1763
17. Harada-Shiba M, Kinoshita M, Kamido H, Shimokado K (1998) Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms. J Biol Chem 273:9681-9687
18. Sudoh N, Toba K, Akishita M, Ako J, Hashimoto M, Iijima K, Kim S, Liang YQ, Ohike Y, Watanabe T, Yamazaki I, Yoshizumi M, Eto M, Ouchi Y (2001) Estrogen prevents oxidative stress-induced endothelial cell apoptosis in rats. Circulation 103:724-729
19. Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, Dimmeler S (2002) Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nat Cell Biol 4:743-749
20. Tschudi MR, Barton M, Bersinger NA, Moreau P, Cosentino F, Noll G, Malinski T, Luscher TF (1996) Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery. J Clin Invest 98:899-905
21. Zeiher AM, Drexler H, Saurbier B, Just H (1993) Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension. J Clin Invest 92:652-662
22. Asai K, Kudej RK, Shen YT, Yang GP, Takagi G, Kudej AB, Geng YJ, Sato N, Nazareno JB, Vatner DE, Natividad F, Bishop SP, Vatner SF (2000) Peripheral vascular endothelial dysfunction and apoptosis in old monkeys. Arterioscler Thromb Vasc Biol 20:1493-1499
23. Fournet-Bourguignon MP, Castedo-Delrieu M, Bidouard JP, Leonce S, Saboureau D, Delescluse I, Vilaine JP, Vanhoutte PM (2000) Phenotypic and functional changes in regenerated porcine coronary endothelial cells: increased uptake of modified LDL and reduced production of NO. Circ Res 86:854-861
24. Fenton M, Barker S, Kurz DJ, Erusalimsky JD (2001) Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries. Arterioscler Thromb Vasc Biol 21:220-226
25. Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC (1999) Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399:597-601
26. Dimmeler S, Fisslthaler B, Fleming I, Hermann C, Busse R, Zeiher AM (1999) Activation of nitric oxide synthase in endothelial cells via Akt-dependent phosphorylation. Nature 399:601-605
27. Chou TC, Yen MH, Li CY, Ding YA (1998) Alterations of nitric oxide synthase expression with aging and hypertension in rats. Hypertension 31:643-648
28. Wilcox JN, Subramanian RR, Sundell CL, Tracey WR, Pollock JS, Harrison DG, Marsden PA (1997) Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. Arterioscler Thromb Vasc Biol 17:2479-2488
29. Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA (1999) Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension 33:1353-1358
30. White CR, Brock TA, Chang LY, Crapo J, Briscoe P, Ku D, Bradley WA, Gianturco SH, Gore J, Freeman BA, Tarpey MM (1994) Superoxide and peroxynitrite in atherosclerosis. Proc Natl Acad Sci U S A 91:1044-1048
31. Finkel T, Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408:239-247
32. Haendeler J, Hoffmann J, Diehl JF, Vasa M, Spyridopoulos I, Zeiher AM, Dimmeler S (2004) Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells. Circ Res 94:768-775
33. van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, Gygi D, Ullrich V, Luscher TF (2000) Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med 192:1731-1744
34. Nagata S (1997) Apoptosis by death factor. Cell 88:355-365
35. Dimmeler S, Haendeler J, Nehls M, Zeiher AM (1997) Suppression of apoptosis by nitric oxide via inhibition of ICE-like and CPP32-like proteases. J Exp Med 185:601-608
36. Li J, Billiar TR, Talanian RV, Kim YM (1997) Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochem Biophys Res Commun 240:419-424
37. Haendeler J, Weiland U, Zeiher AM, Dimmeler S (1997) Effects of redox-related congeners on apoptosis and caspase-3 activity. Nitric Oxide 1:282-293
38. Holmgren A (1989) Thioredoxin and glutaredoxin systems. J Biol Chem 264:13963-13966
39. Holmgren A (2000) Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid Redox Signal 2:811-820
40. Greider CW (1996) Telomere length regulation. Annu Rev Biochem 65:337-365
41. Greider CW, Blackburn EH (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413
42. Vasa M, Breitschopf K, Zeiher AM, Dimmeler S (2000) Nitric oxide activates telomerase and delays endothelial cell senescence. Circ Res 87:540-542