Regulation of radiation-induced protein kinase Cδ activation in radiation-induced apoptosis differs between radiosensitive and radioresistant mouse thymic lymphoma cell lines

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 595, Issue 1-2, 2006, Pages 29-36

  Nakajima, Tetsuo ^a   Yukawa, Osami ^a   Tsuji, Hideo ^a   Ohyama, Harumi ^a   Wang, Bing ^a   Tatsumi, Kouichi ^a   Hayata, Isamu ^a   Hama Inaba, Hiroko ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Ataxia telangiectasia; Mouse thymic lymphoma; Protein kinase C ; Radiation sensitivity; Radiation induced apoptosis

Indexed keywords

ATM PROTEIN; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; ROTTLERIN; SMALL INTERFERING RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL TYPE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; ENZYME ACTIVATION; ENZYME DEGRADATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION; RADIOSENSITIVITY; REGULATORY MECHANISM; THYMOMA; THYMUS LYMPHOMA; WILD TYPE;

ACETOPHENONES; ANIMALS; APOPTOSIS; BENZOPYRANS; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LYMPHOMA; MICE; PROTEIN KINASE C-DELTA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; RADIATION; RADIATION TOLERANCE; RNA, SMALL INTERFERING; SUBCELLULAR FRACTIONS; THYMUS NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; ATAXIA TELANGIECTASIA;

EID: 33244478735     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.10.008     Document Type: Article

References (29)

1. M. Harms-Ringdahl, P. Nicotera, and I.R. Radford Radiation induced apoptosis Mutat. Res. 366 1996 171 179
2. M.F. Lavin, D. Watters, and Q. Song Role of protein kinase activity in apoptosis Experientia 52 1996 979 994
3. R.A. Franklin, and J.A. McCubrey Kinases: positive and negative regulators of apoptosis Leukemia 14 2000 2019 2034
4. P. Dent, A. Yacoub, J. Contessa, R. Caron, G. Amorino, K. Valerie, M.P. Hagan, S. Grant, and R. Schmidt-Ullrich Stress and radiation-induced activation of multiple intracellular signaling pathways Radiat. Res. 159 2003 283 300
5. Y. Nishizuka Protein kinase C and lipid signaling for sustained cellular responses FASEB J. 9 1995 484 496
6. D.E. Hallahan, S. Virudachalam, J.L. Schwartz, N. Panje, R. Mustafi, and R.R. Weichselbaum Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation Radiat. Res. 129 1992 345 350
7. S.-J. Lee, C.-K. Cho, S.-Y. Yoo, T.-H. Kim, and Y.-S. Lee Influence of ionizing radiation on induction of apoptotic cell death and cellular redistribution of protein kinase C isozymes in mouse epidermal cells differing in carcinogenesis stages Mutat. Res. 426 1999 41 49
8. 2-M arrest Cell Growth Differ. 13 2002 237 246
9. M. Spitaler, B. Wiesenhofer, V. Biedermann, T. Seppi, J. Zimmermann, H. Grunicke, and J. Hofmann The involvement of protein kinase C isoenzymes α, ε and ζ, in the sensitivity to antitumor treatment and apoptosis induction Anticancer Res. 19 1999 3969 3976
10. T. Nakajima, O. Yukawa, C. Azuma, H. Ohyama, B. Wang, S. Kojima, I. Hayata, and H. Hama-Inaba Involvement of protein kinase C-related anti-apoptosis signaling in radiation-induced apoptosis in murine thymic lymphoma (3SBH5) cells Radiat. Res. 161 2004 528 534
11. M.F. Denning, Y. Wang, B.J. Nickoloff, and T. Wrone-Smith Protein kinae Cδ is activated by caspase-dependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes J. Biol. Chem. 273 1998 29995 30002
12. Z.-M. Yuan, T. Utsugisawa, T. Ishiko, S. Nakada, Y. Huang, S. Kharbanda, R. Weichselbaum, and D. Kufe Activation of protein kinase Cδ by the c-Ab1 tyrosine kinase in response to ionizing radiation Oncogene 16 1998 1643 1648
13. Y. Emoto, Y. Manome, G. Meinhardt, H. Kisaki, S. Kharbanda, M. Robertson, T. Ghayur, W.W. Wong, R. Kamen, R. Weichselbaum, and D. Kufe Proteolytic activation of protein kinase Cδ by an ICE-like protease in apoptotic cells EMBO J. 14 1995 6148 6156
14. K. Yoshida, H.-G. Wang, Y. Miki, and D. Kufe Protein kinase Cδ is responsible for constitutive and DNA damage-induced phosphorylation of Rad9 EMBO J. 22 2003 1431 1441
15. A. Bharti, S.-K. Kraeft, M. Gounder, P. Pandey, S. Jin, Z.-M. Yuan, S.P. Lees-Miller, R. Weichselbaum, D. Weaver, L.B. Chen, D. Kufe, and S. Kharbanda Inactivation of DNA-dependent protein kinase by protein kinase Cδ: implications for apoptosis Mol. Cell Biol. 18 1998 6719 6728
16. M. Blass, I. Kronfeld, G. Kazimirsky, P.M. Blumberg, and C. Brodie Tyrosine phosphorylation of protein kinase Cδ is essential for its apoptotic effect in response to etoposide Mol. Cell Biol. 22 2002 182 195
17. A. Goerke, N. Sakai, E. Gutjahr, W.A. Schlapkohl, J.F. Mushinski, H. Haller, W. Kolch, N. Saito, and H. Mischak Induction of apoptosis by protein kinase Cδ is independent of its kinase activity J. Biol. Chem. 277 2002 32054 32062
18. : PKCδ promotes cellular survival and chemotherapeutic resistance Cancer Res. 63 2003 780 786
19. M.A. McCracken, L.J. Miraglia, R.A. McKay, and J.S. Strobl Protein kinase Cδ is a prosurvival factor in human breast tumor cell lines Mol. Cancer Ther. 2 2003 273 281
20. H. Hama-Inaba, B. Wang, M. Mori, T. Matsushima, T. Saitoh, M. Takusagawa, T. Yamada, M. Muto, and H. Ohyama Radio-sensitive murine thymoma cell line 3SB: characterization of its apoptosis-resistant variants induced by repeated X-irradiation Mutat. Res. 403 1998 85 94
21. K.-H. Herzog, M.J. Chong, M. Kapsetaki, J.I. Morgan, and P.J. McKinnon Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system Science 280 1998 1089 1091
22. Y. Xu, and D. Baltimore Dual roles of ATM in the cellular response to radiation and in cell growth control Genes Dev. 10 1996 2401 2410
23. H. Tsuji, H. Ishii-Ohba, H. Ukai, T. Katsube, and T. Ogiu Radiation-induced deletions in the 5′ end region of Notch1 lead to the formation of truncated proteins and are involved in the development of mouse thymic lymphomas Carcinogenesis 24 2003 1257 1268
24. I. Fruno-Fukushi, K. Masumura, T. Furuse, Y. Noda, M. Takahagi, T. Saito, Y. Hoki, H. Suzuki, A. Wynshaw-Boris, T. Nohmi, and K. Tatsumi Effect of Atm disruption on spontaneously arising and radiation-induced deletion mutations in mouse liver Radiat. Res. 160 2003 549 558
25. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J. Biol. Chem. 193 1951 265 275
26. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
27. I. Yasuda, A. Kishimoto, S. Tanaka, M. Tominaga, A. Sakurai, and Y. Nishizuka A synthetic peptide substrate for selective assay of protein kinase C Biochem. Biophys. Res. Commun. 166 1990 1220 1227
28. D.G. Bebb, P.J. Warrington, G. de Jong, Z. Yu, J.A. Moffat, K. Skov, S. Spacey, K. Gelmon, and B.W. Glickman Radiation induced apoptosis in ataxia telangiectasia homozygote, heterozygote and normal cells Mutat. Res. 476 2001 13 20
29. M.J. Chong, M.R. Murray, E.C. Gosink, H.R.C. Russell, A. Srinivasan, M. Kapsetaki, S.J. Korsmeyer, and P.J. McKinnon Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system Proc. Natl. Acad. Sci. U.S.A. 97 2000 889 894