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Volumn 41, Issue 1, 2006, Pages 16-26
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Optimization of a pharmacophore model for 5-HT4 agonists using CoMFA and receptor based alignment
a
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Author keywords
5 HT4; 5 Hydroxytryptamine; Agonist; CoMFA; Receptor
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Indexed keywords
2 [(4 ACETAMIDOPIPERIDINYL)ETHYL] 4 AMINO 5 CHLORO 2 METHOXYBENZOATE;
2,3 DIHYDRO 3 ISOPROPYL 2 OXO 1 BENZIMIDAZOLECARBOXYLIC ACID 3ALPHA TROPANYLAMIDE;
3 [(5 HYDROXY 1H INDOL 3 YL)METHYLENE]CARBAZIMADAMIDE;
4 AMINO 5 CHLORO 2 METHOXYBENZOIC ACID 2 (1 PIPERIDINYL)ETHYL ESTER;
4 AMINO 5 CHLORO N [2 (1 DIMETHYLAMINO 1 CYCLOHEXYL)ETHYL] 2 METHOXYBENZAMIDE;
5 BENZYLOXYTRYPTAMINE;
CISAPRIDE;
DAU 6236;
METOCLOPRAMIDE;
N [2 (5 METHOXY 1H INDOL 3 YL)ETHYL] 2 THIOPHENEACETAMIDE;
N [2 (5 METHOXY 1H INDOL 3 YL)ETHYL] 2 THIOPHENEMETHANEAMINE;
N [2 (5 METHOXY 1H INDOL 3 YL)ETHYL],9N METHYL 1H INDOL 2 YL)METHANEAMINE;
N [2 (METHOXY 1H INDOL 3 YL)ETHYL] N (3 PYRIDINYLMETHYL) 1 ETHANAMINE;
N PENTYL 3 [(5 HYDROXY 1H INDOL 3 YL)METHYLENE]CARBAZIMADAMIDE;
N PHENYLETHYL 3 [(5 HYDROXY 1H INDOL 3 YL)METHYLENE]CARBAZIMADAMIDE;
SEROTONIN;
SEROTONIN 4 AGONIST;
UNCLASSIFIED DRUG;
YM 36912;
ZACOPRIDE;
ANIMAL TISSUE;
ARTICLE;
BIOASSAY;
COMPARATIVE MOLECULAR FIELD ANALYSIS;
CONTROLLED STUDY;
DRUG BINDING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ELECTRICITY;
GUINEA PIG;
NONHUMAN;
PHARMACOPHORE;
BINDING SITES;
DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS;
DRUG DESIGN;
LIGANDS;
MODELS, MOLECULAR;
MOLECULAR CONFORMATION;
MOLECULAR STRUCTURE;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
RECEPTORS, SEROTONIN, 5-HT4;
SEROTONIN AGONISTS;
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EID: 33244462168
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/j.ejmech.2005.07.017 Document Type: Article |
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Times cited : (18)
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References (24)
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