Immunocontraceptive effects on female rabbits infected with recombinant myxoma virus expressing rabbit ZP2 or ZP3

Biology of Reproduction

Volumn 74, Issue 3, 2006, Pages 511-521

  Mackenzie, S M ^a   Mclaughlin, E A ^b   Perkins, H D ^c   French, N ^a   Sutherland, T ^a   Jackson, R J ^a   Inglis, B ^c   Muller W J ^a   Van Leeuwen, B H ^c   Robinson, A J ^a   Kerr, Peter ^a,c  

^a CSIRO   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Autoimmunity; Female reproductive tract; Immunocontraception; Immunology; Myxoma virus; Rabbits; Zona pellucida 3

Indexed keywords

ANTIBODY; ANTIGEN; GLYCOPROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; ZONA PELLUCIDA PROTEIN 2; ZONA PELLUCIDA PROTEIN 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN PRESENTATION; ARTICLE; AUTOIMMUNITY; BREEDING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE SEQUENCE; HISTOLOGY; HYDROPHOBICITY; IMMUNE RESPONSE; IMMUNOCONTRACEPTION; INFERTILITY; INFLAMMATION; MYXOMA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; T LYMPHOCYTE; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; ZONA PELLUCIDA;

ANIMALS; ANIMALS, WILD; AUSTRALIA; AUTOANTIBODIES; AUTOANTIGENS; CONTRACEPTION, IMMUNOLOGIC; EGG PROTEINS; FEMALE; INFERTILITY, FEMALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MYXOMA VIRUS; OVARY; PEST CONTROL; PLASMIDS; POXVIRIDAE INFECTIONS; RABBITS; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; T-LYMPHOCYTES;

ANIMALIA; MYXOMA VIRUS; ORYCTOLAGUS CUNICULUS;

EID: 33144486115     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.105.046268     Document Type: Article

References (42)

1. Millar SE, Chamow SM, Baur AW, Oliver C, Robey F, Dean J. Vaccination with a synthetic zona pellucida peptide produces long-term contraception in female mice. Science 1989; 246:953-958.
2. Miller LA, Johns BE, Killian GJ. Immunocontraception of white-tailed deer using native and recombinant zona pellucida vaccines. Anim Reprod Sci 2000; 63:187-195.
3. Wood DM, Liu C, Dunbar BS. Effect of alloimmunization and heteroimmunization with zonae pellucidae on fertility in rabbits. Biol Reprod 1981; 25:439-450.
4. Turner JW Jr., Liu IK, Flannagan DR, Bynum KS, Rutberg AT. Porcine zona pellucida (PZP) immunization of wild horses (Equus caballus) in Nevada: a 10 year study. Reproduction 2002; 60:177-186.
5. Fayrer-Hosken RA, Grobler D, Van Altena JJ, Bertschinger HJ, Kirkpatrick JF. Immunocontraception of African Elephants. Nature 2000; 407:149.
6. Tyndale-Biscoe CH. Virus-vectored immunocontraception of feral mammals. In: Immunological Control of Fertility: From Gametes to Gonads. Reprod Fertil Dev 1994; 6:9-16.
7. Twigg LE, Lowe TJ, Martin GR, Wheeler AG, Gray GS, Griffin SL, O'Reilly CM, Robinson DJ, Hubach PH. Effects of surgically imposed sterility on free-ranging rabbit populations. J Appl Ecol 2000; 37:16-39.
8. Kerr PJ, Jackson JR. Myxoma virus as a vaccine vector for rabbits: antibody levels to influenza virus haemagglutinin presented by a recombinant myxoma virus. Vaccine 1995; 13:1722-1726.
9. Gu W, Holland M, Janssens P, Kerr P. Antibody response in the female rabbit reproductive tract to influenza haemagglutinin encoded by a recombinant myxoma virus. Virology 2003; 313:286-295.
10. Kerr PJ, Jackson RJ, Robinson AJ, Swan J, Silvers L, French N, Clarke H, Hall DF, Holland MK. Infertility in female rabbits (Oryctolagus cuniculus) alloimmunized with the rabbit zona pellucida protein ZPB either as a purified recombinant protein or expressed by recombinant myxoma virus. Biol Reprod 1999; 61:606-613.
11. Gu W, Holland M, Janssens P, Seamark R, Kerr P. Immune response in rabbit ovaries following infection of a recombinant myxoma virus expressing rabbit zona pellucida protein B. Virology 2004; 318:516-523.
12. Harris JD, Hibler DW, Fontenot GK, Hsu KT, Yurewicz EC, Sacco AG. Cloning and characterization of zona pellucida genes and cDNAs from a variety of mammalian species: the ZPA, ZPB and ZPC gene families. DNA Seq 1994; 4:361-393.
13. Dunbar BS, Avery S, Lee V, Prasad S, Schwahn D, Schwoebel E, Skinner S, Wilkins B. The mammalian zona pellucida: its biochemistry, immunochemistry, molecular biology, and developmental expression. In: Immunological Control of Fertility: From Gametes to Gonads. Reprod Fertil Dev 1994; 6:59-76.
14. Prasad SV, Skinner SM, Carino C, Wang N, Cartwright J, Dunbar BS. Structure and function of the proteins of the mammalian zona pellucida. Cells Tissues Organs 2000; 166:148-164.
15. Spargo SC, Hope RM. Evolution and nomenclature of the zona pellucida gene family. Biol Reprod 2003; 68:358-362.
16. Skinner SM, Prasad SV, Ndolo TM, Dunbar BS. Zona pellucida antigens: targets for contraceptive vaccines. Am J Reprod Immunol 1996; 35:163-174.
17. Benoff S. Carbohydrates and fertilization: an overview. Mol Hum Reprod 1997; 3:599-637.
18. Jones GR, Sacco AG, Subramanian MG, Kruger M, Zhang S, Yurewicz EC, Moghissi KS. Histology of ovaries of female rabbits immunized with deglycosylated zona pellucida macromolecules of pigs. Reprod Fertil 1992; 95:513-525.
19. Prasad SV, Mujtaba S, Lee VH, Dunbar BS. Immunogenicity enhancement of recombinant rabbit 55 kDa zona pellucida protein expressed using the baculovirus expression system. Biol Reprod 1995; 52:1167-1178.
20. Prasad SV, Wilkins B, Skinner SM, Dunbar BS. Evaluating zona pellucida structure and function using antibodies to rabbit 55 kDa ZP protein expressed in baculovirus expression system. Mol Reprod Dev 1996; 43:519-529.
21. Mahi-Brown CA, Moran F. Response of cynomolgus macaques to immunization against a synthetic peptide from the human zona pellucida. J Med Primatol 1995; 24:258-270.
22. Dunbar BS, Prasad S, Carino C, Skinner SM. The ovary as an immune target. J Soc Gynecol Investig 2001; 8:S43-S48.
23. Hardy CM, ten Have JF, Pekin J, Beaton S, Jackson RJ, Clydesdale G. Contraceptive responses of mice immunized with purified recombinant mouse zona pellucida subunit 3 (mZP3) proteins. Reproduction 2003; 126:49-59.
24. Skinner SM, Mills T, Kirchick HJ, Dunbar BS. Immunization with zona pellucida proteins results in abnormal ovarian follicular differentiation and inhibition of gonadotropin-induced steroid secretion. Endocrinology 1984; 115:2418-2432.
25. Sehgal S, Gupta SK, Bhatnagar P. Long-term effects of immunization with porcine zona pellucida on rabbit ovaries. Pathology 1989; 21:105-110.
26. Jackson RJ, Maguire DJ, Hinds LA, Ramshaw IA. Infertility in mice induced by a recombinant ectromelia virus expressing mouse zona pellucida glycoprotein 3. Biol Reprod 1998; 58:152-159.
27. Lloyd ML, Shellam GR, Papadimitriou JM, Lawson MA. Immunocontraception is induced in BALB/c mice inoculated with murine cytomegalovirus expressing mouse zona pellucida 3. Biol Reprod 2003; 68:2024-2032.
28. Lee VH, Dunbar BS. Developmental expression of the rabbit 55-kDa zona pellucida protein and messenger RNA in ovarian follicles. Dev Biol 1993; 155:371-382.
29. Davison AJ, Moss B. Structure of vaccinia virus late promoters. J Mol Biol 1989; 210:771-784.
30. Russell RJ, Robbins SJ. Cloning and molecular characterization of the myxoma virus genome. Virology 1989; 170:147-159.
31. Carol MW, Moss B. E. coli beta-glucuronidase (GUS) as a marker for recombinant vaccinia viruses. Biotechniques 1995; 19:352-354.
32. Jackson RJ, Hall DF, Kerr PJ. Construction of recombinant myxoma viruses expressing foreign genes from different intergenic sites without associated attenuation. J Gen Virol 1996; 77:1569-1575.
33. Cao JX, Upton C. gpt-gus fusion gene for selection and marker in recombinant poxviruses. Biotechniques 1997: 22;276-278.
34. Fuerst TR, Niles EG, Studier FW, Moss B. Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesises bacteriophage T7 RNA polymerase. Proc Natl Acad Sci U S A 1986; 83:8122-8126.
35. Moss B, Elroy-Stein O, Mizukami T, Alexander WA, Fuerst TR. New mammalian expression vectors. Nature 1990; 248:91-92.
36. Elroy-Stein O, Fuerst TR, Moss B. Cap-independent translation of mRNA conferred by encephalomyocarditis virus 5′ sequence improves the performance of the vaccinia virus/bacteriophage T7 hybrid expression system. Proc Natl Acad Sci U S A 1989; 86:6126-6130.
37. Elroy-Stein O, Moss B. Gene expression using the vaccinia virus/T7 RNA polymerase hybrid system. In: Current Protocols in Molecular Biology, vol. 3. Hoboken: John Wiley and Sons Inc; 1998:16.19.11.
38. Gallagher S, Winston SE, Fuller SA, Hurrell JGA. Immunoblotting and immunodetection. In: Current Protocols in Molecular Biology, vol. 2. Hoboken: John Wiley and Sons Inc; 1993:10.18.11-10.18.17.
39. Best SM, Kerr PJ. Coevolution of host and virus: the pathogenesis of virulent and attenuated strains of myxoma virus in resistant and susceptible European rabbits. Virology 2000; 267:36-48.
40. Kerr P, McFadden G. Immune responses to myxoma virus. Viral Immunol 2002; 15:229-246.
41. Kerr PJ. An ELISA for epidemiological studies of myxomatosis: persistence of antibodies to myxoma virus in European rabbits (Oryctolagus cuniculus). Wildl Res 1997; 24:53-65.
42. Traggiai E, Puzone R, Lanzavacchia A. Antigen dependent and independent mechanisms that sustain serum antibody titres. Vaccine 2003; 21:S235-S237.