When may adjuvant radiotherapy be avoided in operable breast cancer?

Clinical Oncology

Volumn 18, Issue 3, 2006, Pages 191-199

  Kunkler, I H ^a,b   Prescott, R J ^a   Williams, L J ^a   King, C C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; TAMOXIFEN;

AGE; BREAST CANCER; BREAST SURGERY; CANCER ADJUVANT THERAPY; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER RESEARCH; CANCER SURVIVAL; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; EVIDENCE BASED MEDICINE; HEALTH CARE COST; HUMAN; LYMPH NODE METASTASIS; MASTECTOMY; ORGAN PRESERVATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; RISK ASSESSMENT; TREATMENT INDICATION;

EID: 33144470215     PISSN: 09366555     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clon.2005.11.005     Document Type: Article

References (57)

1. S. Hellman Natural history of small breast cancers J Clin Oncol 12 1994 2229-2234
2. D. Dodwell K. Horgan Breast cancer: Loco-regional control and survival Clin Oncol 13 2001 172-173
3. M. Overgaard P.A. Hansen J. Overgaard et. al. Postoperative radiotherapy in high risk premenopausal women with breast cancer who receive adjuvant chemotherapy N Engl J Med 337 1997 949-955
4. J. Ragaz S.M. Jackson N. Le et. al. Postoperative radiotherapy in high-risk postmenopausal women with breast cancer N Engl J Med 337 1997 956-962
5. J. Ragaz I.A. Olivotto J.J. Spinelli et. al. Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomised trial J Natl Cancer Inst 97 2005 116-126
6. M. Overgaard M.B. Jensen J. Overgaard et. al. Postoperative radiotherapy in high-risk postmenopausal breast cancer patients who receive adjuvant chemotherapy Lancet 353 1999 1641-1648
7. M. Overgaard Update of the Danish trials of postoperative radiotherapy in high-risk breast cancer patients given adjuvant systemic therapy H.D. Kogelnik P. Lukas F. Sedlmayer Progress in radio-oncology VII 2002 Monduzzi Editore Bologna
8. Scottish Executive. Cancer scenarios: An aid to planning cancer services in Scotland. Scottish Executive, May 2001.
9. S.G. Diab R.M. Elledge G.M. Clark Tumor characteristics and clinical outcome of elderly women with breast cancer J Natl Cancer Inst 2000 550-556
10. R. Ballard-Barbash A.L. Potosky L.C. Harlan et. al. Factors associated with surgical and radiation therapy for early stage breast cancer in older women J Natl Cancer Inst 88 1996 716-726
11. Scottish Intercollegiate Guidelines Network. Breast cancer in women. A national clinical guideline. SIGN publication no 29, 1998.
12. J. Kurtz EUSOMA working party. The curative role of radiotherapy in the treatment of operable breast cancer Eur J Cancer 38 2002 1961-1974
13. Y. Zissiadis A. Langlands B. Barraclough et. al. Breast conservation: long term results from Westmead Hospital Aust NZ J Surg 67 1997 313-319
14. M. Extermann Measuring comorbidity in older cancer patients Eur J Cancer 36 2000 453-471
15. Early Breast Cancer Trialists' Collaborative Group Favourable and unfavourable effects on long-term survival for early breast cancer: An overview of the randomised trials Lancet 355 2000 1757-1770
16. B. Fisher S. Anderson C.K. Redmond et. al. Reanalysis and results after 12 years of follow up in a randomised clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer N Engl J Med 333 1995 456-1461
17. R.M. Clark T. Whelan M.E. Levine et. al. Randomised clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: An update. Ontario Breast Cancer Study Group J Natl Cancer Inst 88 1996 1659-1664
18. A.P. Forrest H.J. Stewart D. Everington et. al. Randomised controlled trial of conservation therapy for breast cancer: 6 years analysis of the Scottish trial. Scottish Cancer Trials Breast Group Lancet 348 1996 708-713
19. R. Sauer A. Wallgren J.M. Kurtz Adjuvant radiotherapy after breast conserving surgery for breast cancer Eur J Cancer 36 2000 1073-1084
20. A. Fortin M. Larochelle J. Laverdiere et. al. Local failure is responsible for the decrease in survival for patients with breast cancer treated with conservative surgery and postoperative radiotherapy J Clin Oncol 17 1999 101-109
21. V. Vinh Hung C. Verschraegen Breast-conserving surgery with or without radiotherapy: Pooled-analysis for risks of ipsilateral tumour recurrence and mortality J Natl Cancer Inst 96 2004 115-121
22. E.R. Fisher S. Anderson C. Redmond et. al. Ipsilateral breast tumor recurrence and survival following lumpectomy and irradiation: pathological findings from NSABP protocol B-06 Semin Surg Oncol 8 1992 161-166
23. Uppsala-Orebro Breast Cancer Study Group Sector resection with or without postoperative radiotherapy for stage I breast cancer: A randomized trial J Natl Cancer Inst 82 1990 277-282
24. G. Liljegren A. Lindgren J. Bergh et. al. Risk factors for local recurrence after conservative treatment in stage I breast cancer. Definition of a subgroup not requiring radiotherapy Ann Oncol 8 1997 235-241
25. R.M. Clark P.B. McCulloch M.N. Levine et. al. Randomised clinical trial to assess the effectiveness of breast irradiation following lumpectomy and axillary dissection for node negative breast cancer J Natl Cancer Inst 84 1992 683-689
26. B. Fisher M. Bauer R. Margolese et. al. Five-year results of a randomised clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer N Engl J Med 312 1985 665-673
27. U. Veronesi A. Luini M. Del Vecchio et. al. Radiotherapy after breast-conserving surgery in women with localized cancer of the breast N Engl J Med 328 1993 1587-1591
28. U. Veronesi B. Salvadori A. Luini et. al. Breast conservation is a safe method in patients with small cancers of the breast. Long-term results of three randomised trials on 1973 patients Eur J Cancer 31A 1995 1574-1579
29. S.J. Schnitt D. McCready L. Manchul et. al. A prospective study of conservative surgery alone in the treatment of selected patients with stage 1 breast cancer Cancer 77 1996 1094-1100
30. K.S. Hughes L.A. Schnapper D. Berry et. al. Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer N Engl J Med 351 2004 971-977
31. V. Sacchini P.I. Borgen Can radiation therapy for breast cancer be avoided? Lancet 364 2004 926-927
32. A.W. Fyles D.R. McCready L.A. Manchul et. al. Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancer N Engl J Med 351 2004 963-970
33. R. Blamey U. Chetty D. George C. Morgan M. Mitchell Update of the BASO II trial of primary treatment of tumours of excellent prognosis Eur J Cancer Suppl 2 2004 161
34. I.H. Kunkler PRIME II breast cancer trial Clin Oncol 16 2004 447-448
35. C. Tinterri W. Gatzemeier C. Andreoli et. al. Breast conservative surgery with and without radiotherapy with early stage breast cancer: A prospective randomised trial [abstract 378] Eur J Cancer Suppl 2 Suppl 3 2004 166
36. A. Goldhirsch J.H. Glick R. Gelber et. al. Meeting highlights: international consensus panel on the treatment of primary breast cancer J Natl Cancer Inst 90 1998 1601-1608
37. J.R. Harris P. Halpin-Murphy M. McNeese et. al. Consensus statement of postmastectomy radiation therapy Int J Radiat Oncol Biol Phys 44 1999 989-990
38. J.A. Van der Hage H. Putter H. Bonnema et. al. Impact of locoregional treatment on the early-stage breast cancer patients: A retrospective analysis Eur J Cancer 39 2003 2192-2199
39. A. Recht S.B. Edge L.S. Solin et. al. Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology J Clin Oncol 19 2001 1539-1569
40. A. Recht H. Bartelink A. Fourquet et. al. Postmastectomy radiotherapy: questions for the twenty-first century J Clin Oncol 16 1998 2886-2889
41. A. Goldhirsch A.S. Coates M. Colleoni R. Gelber Radiotherapy and chemotherapy in high-risk breast cancer N Engl J Med 338 1998 330
42. A. Recht R. Gray N.E. Davidson et. al. Loco-regional failure ten years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation. Experience of the Eastern Cooperative Oncology Group J Clin Oncol 17 1999 1689-1700
43. M.M. Kaufmann W. Jonat U. Abel et. al. Adjuvant randomized trials of doxorubicin/cyclophosphamide versus doxorubcin/cyclophamide/tamoxifen and CMF chemotherapy versus tamoxifen in women with node positive breast cancer J Clin Oncol 11 1993 454-460
44. T. Whelan M. Levine More evidence that locoregional radiation therapy improves survival: What should we do? J Natl Cancer Inst 97 2005 82-84
45. E. Ceilley R. Jagel S. Goldberg et. al. Radiotherapy for invasive breast cancer in North America and Europe: Results of a survey Int J Radiat Oncol Biol Phys 61 2005 365-373
46. M. Voordeckers J. Van de Steene V. Vinh Hung et. al. Adjuvant radiotherapy after mastectomy for pT1-pT2 node negative breast cancer (pN0): Is it worth the effort? Radiother Oncol 68 2003 227-231
47. Kunkler IH, Price A, Dixon JM, et al. SUPREMO (Selective Use of Postoperative Radiotherapy after Mastectomy): A phase III randomised trial assessing the role of postmastectomy chest wall irradiation in 'intermediate risk' women with operable breast cancer receiving adjuvant systemic therapy. International Congress of Radiation Research, Brisbane, Australia, 17-22 August 2003, poster abstract no 1159.
48. B. Fowble R. Gray K. Gilchrist et. al. Identifications of a subgroup of patients with breast cancer and histologically positive nodes receiving adjuvant chemotherapy who may benefit from postmastectomy radiotherapy J Clin Oncol 6 1988 1107-1117
49. H.F. Sykes D.A. Sims C.J. Wong et. al. Loco-regional recurrence in breast cancer after mastectomy and adriamycin-based adjuvant chemotherapy: Evaluation of the role of postoperative radiotherapy Int J Radiat Oncol Biol Phys 16 1989 641-647
50. T.M. Pisanskya J.N. Ingle D.J. Schald et. al. Patterns of tumour relapse following mastectomy and adjuvant systemic therapy in patients with axillary lymph node positive breast cancer Cancer 72 1993 1247-1260
51. A. Katz E.A. Strom T.A. Buchholz et. al. Loco-regional recurrence patterns after mastectomy and doxo-rubicin-based chemotherapy: implications for postoperative irradiation J Clin Oncol 18 2000 2817-2827
52. A.C. Voogd M. Nielsen J.L. Peterse et. al. Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage 1 and II breast cancer: Pooled results of two large European randomised trials J Clin Oncol 19 2001 1688-1697
53. S. O'Rourke M.H. Galea D. Morgan et. al. Local recurrence after simple mastectomy Br J Surg 81 1994 386-389
54. A. Howells J. Cuzick M. Baum et. al. Results of the ATAC (arimidex, tamoxifen, alone or in combination) trial after completion of 5 years of adjuvant treatment Lancet 365 2005 60-62
55. J.A. Hayman B.E. Hillner J.R. Harris et. al. Cost effectiveness of routine radiation therapy following conservative surgery for early-stage breast cancer J Clin Oncol 16 1998 1022-1029
56. S. Koscielny M. Tubiana The link between local recurrence and distant metastases in human breast cancer Int J Radiat Oncol Biol Phys 43 1999 11-24
57. G. Liljegren L. Holmberg H.O. Adami G. Westman S. Graffman J. Bergh Sector resection with or without postoperative radiotherapy for stage I breast cancer: Five-year results of a randomised trial J Natl Cancer Inst 86 1994 718-722