Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy

Kidney International

Volumn 68, Issue 6, 2005, Pages 2599-2607

  Coombes, Jason D ^b   Mreich, Ellein ^b   Liddle, Christopher ^b   Rangan, Gopala K ^a  

^a WESTMEAD HOSPITAL   (Australia)

^b NONE

Author keywords

Glomerular disease; Proteinuria; Sirolimus

Indexed keywords

BOVINE SERUM ALBUMIN; BROXURIDINE; CYCLIN D; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYTOPLASM PROTEIN; DIMETHYL SULFOXIDE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; RAPAMYCIN; ROSCOVITINE;

ACUTE KIDNEY FAILURE; ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LABELING; CELL SWELLING; CONTROLLED STUDY; DISEASE SEVERITY; EPITHELIUM CELL; FEMALE; HYPERCHOLESTEROLEMIA; KIDNEY DISEASE; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; KIDNEY STRUCTURE; KIDNEY TUBULE CELL; KIDNEY TUBULE DISORDER; KIDNEY TUBULE EPITHELIUM; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN OVERLOAD NEPHROPATHY; RAT;

ANIMALS; APOPTOSIS; CELL DIVISION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; CYTOPLASM; EPITHELIAL CELLS; FEMALE; GROWTH INHIBITORS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY CORTEX; KIDNEY FAILURE, ACUTE; KIDNEY TUBULES; MONOCYTES; PROTEINURIA; PURINES; RATS; RATS, WISTAR; SERUM ALBUMIN, BOVINE; SIROLIMUS;

EID: 32844460416     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2005.00732.x     Document Type: Article

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