Identification of molecular targets for immunotherapy of patients with head and neck squamous cell carcinoma

Oral Oncology

Volumn 42, Issue 3, 2006, Pages 306-316

  Dasgupta, Santanu ^a   Tripathi, Pulak K ^a   Qin, Hongxing ^a   Bhattacharya Chatterjee, Malaya ^a   Valentino, Joseph ^b   Chatterjee, Sunil K ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Head and neck cancer; Immunotherapy; Microarray; Overexpressed genes; Real time RT PCR

Indexed keywords

AREG PROTEIN; CDH3 PROTEIN; KLK10 PROTEIN; MESSENGER RNA; NMU PROTEIN; PROTEIN; SLPI PROTEIN; UNCLASSIFIED DRUG;

ANAX3 GENE; AREG GENE; ARTICLE; CANCER CELL; CANCER SCREENING; CDH3 GENE; CONTROLLED STUDY; FIBROBLAST; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC CODE; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; KLK10 GENE; LARYNX CARCINOMA; MAJOR CLINICAL STUDY; MAL2 GENE; MICROARRAY ANALYSIS; NMU GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLE; SLPI GENE; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; GENE EXPRESSION; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOTHERAPY; MICROARRAY ANALYSIS; NEOPLASM PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL;

EID: 32644490533     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2005.08.007     Document Type: Article

References (45)

1. R.T. Greenlee, M.B. Hill-Harmon, T. Murray, and M. Thun Cancer statistics, 2001 CA Cancer J Clin 51 1 2001 15 36
2. M.A. Ginos, G.P. Page, and B.S. Michalowicz Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck Cancer Res 64 1 2004 55 63
3. D. Hardisson Molecular pathogenesis of head and neck squamous cell carcinoma Eur Arch Otorhinolaryngol 260 9 2003 502 508
4. Y. Yoshitake, T. Nakatsura, and M. Monji Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis Clin Cancer Res 10 19 2004 6437 6448
5. G. Russo, C. Zegar, and A. Giordano Advantages and limitations of microarray technology in human cancer Oncogene 22 42 2003 6497 6507
6. A. Cromer, A. Carles, and R. Millon Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis Oncogene 23 14 2004 2484 2498
7. P. Roepman, L.F. Wessels, and N. Kettelarij An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas Nat Genet 37 2 2005 182 186
8. S. Dasgupta, M. Bhattacharya-Chatterjee, B.W. O'Malley Jr., and S.K. Chatterjee Reversal of immune suppression following vaccination with recombinant vaccinia virus expressing IL-2 in an orthotopic murine model of head and neck squamous cell carcinoma Cancer Ther 2 2004 375 388
9. B.W. O'Malley Jr., K.A. Cope, C.S. Johnson, and M.R. Schwartz A new immunocompetent murine model for oral cancer Arch Otolaryngol Head Neck Surg 123 1 1997 20 24
10. H. Qin, J. Valentino, and S. Manna Gene therapy for head and neck cancer using vaccinia virus expressing IL-2 in a murine model, with evidence of immune suppression Mol Ther 4 6 2001 551 558
11. S. Dasgupta, P.K. Tripathi, M. Bhattacharya-Chatterjee, B. O'Malley Jr., and S.K. Chatterjee Recombinant vaccinia virus expressing IL-2 generates effective anti-tumor responses in an orthotopic murine model of head and neck carcinoma Mol Ther 8 2 2003 238 248
12. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley Jr BW, Chatterjee SK. Vaccination with recobinant vaccinia virus expressing interleukin-2 invokes anti-tumor cellular immunity in an orthotopic murine model of head and neck squamous cell carcinoma. Mol Ther 2005, in press.
13. J.W. Hodge, J.P. McLaughlin, J.A. Kantor, and J. Schlom Diversified prime and boost protocols using recombinant vaccinia virus and recombinant non-replicating avian pox virus to enhance T-cell immunity and antitumor responses Vaccine 15 6-7 1997 759 768
14. M.Z. Zhu, J. Marshall, D. Cole, J. Schlom, and K.Y. Tsang Specific cytolytic T-cell responses to human CEA from patients immunized with recombinant avipox-CEA vaccine Clin Cancer Res 6 1 2000 24 33
15. E.T. Liu Classification of cancers by expression profiling Curr Opin Genet Dev 13 1 2003 97 103
16. G.A. Jeon, J.S. Lee, and V. Patel Global gene expression profiles of human head and neck squamous carcinoma cell lines Int J Cancer 112 2 2004 249 258
17. T. Yuen, E. Wurmbach, R.L. Pfeffer, B.J. Ebersole, and S.C. Sealfon Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays Nucleic Acids Res 30 10 2002 e48
18. S.D. Billings, M.D. Southall, and T. Li Amphiregulin over-expression results in rapidly growing keratinocytic tumors: an in vivo xenograft model of keratoacanthoma Am J Pathol 163 6 2003 2451 2458
19. D.E. Hansel, A. Rahman, and M. Hidalgo Identification of novel cellular targets in biliary tract cancers using global gene expression technology Am J Pathol 163 1 2003 217 229
20. I. Takemasa, H. Higuchi, and H. Yamamoto Construction of preferential cDNA microarray specialized for human colorectal carcinoma: molecular sketch of colorectal cancer Biochem Biophys Res Commun 285 5 2001 1244 1249
21. S. LeJeune, R. Leek, E. Horak, G. Plowman, M. Greenall, and A.L. Harris Amphiregulin, epidermal growth factor receptor, and estrogen receptor expression in human primary breast cancer Cancer Res 53 15 1993 3597 3602
22. I.M. Berquin, M.L. Dziubinski, G.P. Nolan, and S.P. Ethier A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin Oncogene 20 30 2001 4019 4028
23. A. D'Antonio, S. Losito, and S. Pignata Transforming growth factor alpha, amphiregulin and cripto-1 are frequently expressed in advanced human ovarian carcinomas Int J Oncol 21 5 2002 941 948
24. M. Ebert, M. Yokoyama, and M.S. Kobrin Induction and expression of amphiregulin in human pancreatic cancer Cancer Res 54 15 1994 3959 3962
25. D.G. Bostwick, J. Qian, and N.J. Maihle Amphiregulin expression in prostatic intraepithelial neoplasia and adenocarcinoma: a study of 93 cases Prostate 58 2 2004 164 168
26. P.K. Ha, N.E. Benoit, and R. Yochem A transcriptional progression model for head and neck cancer Clin Cancer Res 9 8 2003 3058 3064
27. K. Taniuchi, H. Nakagawa, and M. Hosokawa Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases Cancer Res 65 8 2005 3092 3099
28. B. Jarzab, M. Wiench, and K. Fujarewicz Gene expression profile of papillary thyroid cancer: sources of variability and diagnostic implications Cancer Res 65 4 2005 1587 1597
29. L.Y. Luo, D. Katsaros, and A. Scorilas The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis Cancer Res 63 4 2003 807 811
30. A. Magklara, A. Scorilas, and D. Katsaros The human KLK8 (neuropsin/ovasin) gene: identification of two novel splice variants and its prognostic value in ovarian cancer Clin Cancer Res 7 4 2001 806 811
31. S.E. Shetzline, R. Rallapalli, and K.J. Dowd Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias Blood 104 6 2004 1833 1840
32. N.I. Euer, S. Kaul, H. Deissler, V.J. Mobus, R. Zeillinger, and U.H. Weidle Identification of L1CAM, Jagged2 and Neuromedin U as ovarian cancer-associated antigens Oncol Rep 13 3 2005 375 387
33. S. Tsukishiro, N. Suzumori, H. Nishikawa, A. Arakawa, and K. Suzumori Use of serum secretory leukocyte protease inhibitor levels in patients to improve specificity of ovarian cancer diagnosis Gynecol Oncol 96 2 2005 516 519
34. S. Ameshima, T. Ishizaki, Y. Demura, Y. Imamura, I. Miyamori, and H. Mitsuhashi Increased secretory leukoprotease inhibitor in patients with nonsmall cell lung carcinoma Cancer 89 7 2000 1448 1456
35. N. Devoogdt, H. Revets, G.H. Ghassabeh, and P. De Baetselier Secretory leukocyte protease inhibitor in cancer development Ann N Y Acad Sci 1028 2004 380 389
36. R.I. Garver Jr., K.T. Goldsmith, B. Rodu, P.C. Hu, E.J. Sorscher, and D.T. Curiel Strategy for achieving selective killing of carcinomas Gene Ther 1 1 1994 46 50
37. I. Zelvyte, A. Wallmark, E. Piitulainen, U. Westin, and S. Janciauskiene Increased plasma levels of serine proteinase inhibitors in lung cancer patients Anticancer Res 24 1 2004 241 247
38. A.K. Abbas, K.M. Murphy, and A. Sher Functional diversity of helper T lymphocytes Nature 383 6603 1996 787 793
39. A.E. Al Moustafa, M.A. Alaoui-Jamali, and G. Batist Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells Oncogene 21 17 2002 2634 2640
40. A.K. El-Naggar, H.W. Kim, and G.L. Clayman Differential expression profiling of head and neck squamous carcinoma: significance in their phenotypic and biological classification Oncogene 21 53 2002 8206 8219
41. Y.C. Hu, K.Y. Lam, S. Law, J. Wong, and G. Srivastava Identification of differentially expressed genes in esophageal squamous cell carcinoma (ESCC) by cDNA expression array: over-expression of Fra-1, Neogenin, Id-1, and CDC25B genes in ESCC Clin Cancer Res 7 8 2001 2213 2221
42. C. Leethanakul, V. Knezevic, and V. Patel Gene discovery in oral squamous cell carcinoma through the Head and Neck Cancer Genome Anatomy Project: confirmation by microarray analysis Oral Oncol 39 3 2003 248 258
43. F. Lemaire, R. Millon, and J. Young Differential expression profiling of head and neck squamous cell carcinoma (HNSCC) Br J Cancer 89 10 2003 1940 1949
44. D.B. Villaret, T. Wang, and D. Dillon Identification of genes over-expressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis Laryngoscope 110 3 Pt 1 2000 374 381
45. S.C. Liu, D.E. Bassi, S.Y. Zhang, D. Holoran, C.J. Conti, and A.J. Klein-Szanto Overexpression of cyclin D2 is associated with increased in vivo invasiveness of human squamous carcinoma cells Mol Carcinog 34 3 2002 131 139