Overexpression of cyclin D2 is associated with increased in vivo invasiveness of human squamous carcinoma cells

Molecular Carcinogenesis

Volumn 34, Issue 3, 2002, Pages 131-139

  Liu, Shao Chen ^a   Bassi, Daniel E ^a   Zhang, Shi Yu ^a   Holoran, Dana ^a   Conti, Claudio J ^b   Klein Szanto, Andres J P ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Cyclin D2; Head and neck; Invasiveness; Squamous carcinoma

Indexed keywords

CYCLIN D2; GELATINASE; KI 67 ANTIGEN; PHOSPHOTRANSFERASE;

ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CANCER TRANSPLANTATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; EXPRESSION VECTOR; GENE OVEREXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LABELING INDEX; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SCID MOUSE; SQUAMOUS CELL CARCINOMA; TRACHEA; TUMOR GROWTH; WESTERN BLOTTING; XENOTRANSPLANTATION;

ANIMALS; CARCINOGENICITY TESTS; CARCINOMA, SQUAMOUS CELL; CYCLINS; HEAD AND NECK NEOPLASMS; HUMANS; MICE; MICE, SCID; NEOPLASM INVASIVENESS; RATS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

MUS MUSCULUS;

EID: 0036301241     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.10057     Document Type: Article

References (43)

1. The Pezcoller lecture: Cancer cell cycles revisited
2. The G1/S cell-cycle in eukaryotic cells
3. Cyclins: CDKs and cancer
4. Mutation of cell cycle regulators: Biological and clinical implications for human neoplasia
5. Cancer cell cycles
6. Amplification and expression of human cyclin D gene in esophageal cancer
7. Coding sequence of the over-expressed transcript of the putative oncogene PRAD1/cyclin D1 in two primary human tumors
8. Overexpression of cyclin D1 in mouse skin carcinogenesis
9. Amplification of cyclin genes in colorectal carcinomas
10. Cyclin D1 protein expression and function in human breast cancer
11. D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1
12. Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer
13. Over-expression of cyclin D1 enhances gene amplification
14. Abundance and subcellular localisation of cyclin D3 in human tumors
15. Prad-1 (CYCLIN D1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma
16. Cyclin D1 gene amplification is a more potent prognostic factor than its protein over-expression in human head and neck squamous cell carcinomas
17. Amplification of the int-2 gene in human head and neck squamous cell carcinomas
18. Cylin D1 abnormalities and tobacco exposure in head and neck squamous cell carcinoma
19. Cyclin D2 overexpression and lack of p27 correlate positively and cyclin E inversely with a poor prognosis in gastric cancer cases
20. Amplification and expression of cyclin D genes (cyclin D1, CCND2 and cyclin D3) in human malignant gliomas
21. Cyclin D1 gene amplification in human laryngeal squamous cell carcinomas: Prognostic significance and clinical implications
22. PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas
23. Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven in a group of fortyseven operable squamous cell carcinomas of head and neck
24. Three distinct keratinocyte subtype identified in human oral epithelium by their patterns of keratin expression in culture and in xenografts
25. The mesothelial keratins: A new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia
26. Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
27. Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression
28. Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cydin D1
29. Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences
30. D-type cyclin-dependent kinase activity in mammalian cells
31. In vivo and in vitro invasiveness of human lung carcinoma cell lines
32. P53 alteration in human squamous cell carcinomas and carcinoma cell lines
33. Multiple breakpoints within the BCL-1 locus in B-cell lymphoma: Rearrangements of the cyclin D1 gene
34. Cyclin D1 expression as a prognostic factor in advanced hypopharyngeal carcinoma
35. Cyclin D1 overexpression correlates with poor prognosis in patients with tongue squamous cell carcinoma
36. Plugging it in: Signaling circuits and the yeast cell cycle
37. Human enhancer of filamentation 1, a novel P130 crk-associated substrate-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae
38. Expression of the retinoblastoma tumor suppressor gene inhibits tumor cell invasion in vitro
39. Overexpression of cyclin D1 induces glioma invasion by increasing matrix metallo-proteinase activity and cell motility
40. Cdk5 gets into sticky situations
41. Proliferation-independent induction of macrophage cyclin D2, and repression of cyclin D1, by lipopolysaccharide
42. The retinoblastoma protein as a transcriptional repressor