EGFR signaling pathway negatively regulates PSA expression and secretion via the PI3K-Akt pathway in LNCaP prostate cancer cells

Biochemical and Biophysical Research Communications

Volumn 342, Issue 1, 2006, Pages 92-100

  Hakariya, Tomoaki ^a   Shida, Yohei ^a   Sakai, Hideki ^a   Kanetake, Hiroshi ^a   Igawa, Tsukasa ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Androgen receptor; EGF receptor; LNCaP C 81 cells; PI3K Akt pathway; PSA

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTATE SPECIFIC ANTIGEN; PROTEIN KINASE B;

ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL STRAIN; CONTROLLED STUDY; ENZYME INHIBITION; HORMONAL REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROGENS; CELL LINE, TUMOR; CHROMONES; DOWN-REGULATION; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MORPHOLINES; NEOPLASM STAGING; ORGANIC CHEMICALS; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 32644486084     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.106     Document Type: Article

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