Smaller white-matter volumes are associated with larger deficits in attention and learning among long-term survivors of acute lymphoblastic leukemia

Cancer

Volumn 106, Issue 4, 2006, Pages 941-949

  Reddick, Wilburn E ^a,b   Shan, Zuyao Y ^a   Glass, John O ^a   Helton, Susan ^a   Xiong, Xiaoping ^a   Wu, Shengjie ^a   Bonner, Melanie J ^c   Howard, Scott C ^a,d   Christensen, Robbin ^a   Khan, Raja B ^a,d   Pui, Ching Hon ^a   Mulhern, Raymond K ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b University of Memphis   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Acute lymphoblastic leukemia; Attention; Image analysis; Magnetic resonance imaging; Neuropsychology; Neurotoxicity

Indexed keywords

CYTARABINE; HYDROCORTISONE; METHOTREXATE;

ACADEMIC ACHIEVEMENT; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; ATTENTION; ATTENTION DEFICIT DISORDER; BRAIN SIZE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVOR; CHILD; COGNITION; CONTROLLED STUDY; FEMALE; HUMAN; INTELLIGENCE; LEARNING DISORDER; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SKULL IRRADIATION; WHITE MATTER;

ADOLESCENT; ATTENTION; BRAIN; CHILD; CHILD, PRESCHOOL; COGNITION DISORDERS; CRANIAL IRRADIATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; INTELLIGENCE TESTS; LEARNING DISORDERS; LEUKEMIA, LYMPHOCYTIC, ACUTE; MAGNETIC RESONANCE IMAGING; MALE; SURVIVORS;

EID: 32544461639     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.21679     Document Type: Article

References (39)

1. Pui C-H, Relling MV, Downing JR. Acute lymphoblastic leukemia. N Engl J Med. 2004;350:1535-1548.
2. Moleski M. Neuropsychological, neuroanatomical, and neurophysiological consequences of CNS chemotherapy for acute lymphoblastic leukemia. Arch Clin Neuropsychol. 2000;15:603-630.
3. Kaemingk KL, Carey ME, Moore IMK, Herzer M, Hutter JJ. Math weaknesses in survivors of acute lymphoblastic leukemia compared to healthy children. Child Neuropsychol. 2004;10:14-23.
4. Raymond-Speden E, Tripp G, Lawrence B, Holdaway D. Intellectual, neuropsychological, and academic functioning in long-term survivors of leukemia. J Pediatr Psychol. 2000;25:59-68.
5. Duffner PK. Long-term effects of radiation therapy on cognitive and endocrine function in children with leukemia and brain tumors. Neurologist. 2004;10:293-310.
6. von der Weid N, Mosimann I, Hirt A, et al. Intellectual outcome in children and adolescents with acute lymphoblastic leukaemia treated with chemotherapy alone: age- and sex-related differences. Eur J Cancer. 2003;37:359-365.
7. McAllister TW, Ahles TA, Saykin AJ, et al. Cognitive effects of cytotoxic cancer chemotherapy: predisposing risk factors and potential treatments. Curr Psychiatr Rep. 2004;364-371.
8. Montour-Proulx I, Kuehn SM, Keene DL, et al. Cognitive changes in children treated for acute lymphoblastic leukemia with chemotherapy only according to the Pediatric Oncology Group 9605 Protocol. J Child Neurol. 2005;20:129-133.
9. Rodgers J, Marckus R, Kearns P, Windebank K. Attentional ability among survivors of leukaemia treated without cranial irradiation. Arch Dis Child. 2003;88:147-150.
10. Schatz J, Kramer JH, Abiin A, Matthay KK. Processing speed, working memory and IQ: a developmental model of cognitive deficits following cranial radiation therapy. Neuropsychology. 2000;14:189-200.
11. Espy KA, Moore IMK, Kaufmann PM, Kramer JH, Matthay K, Hutter JJ. Chemotherapeutic CNS prophylaxis and neuropsychologic change in children with acute lymphoblastic leukemia: a prospective study. J Pediatr Psychol. 2001;26:1-9.
12. Waber DP. More good news about neuropsychological late effects in long-term survivors of acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2002;24:86-87.
13. Kingma A, van Dommelen RI, Mooyaart EL, Wilmink JT, Deelman BG, Kamps WA. No major cognitive impairment in young children with acute lymphoblastic leukemia using chemotherapy only: a prospective longitudinal study. J Pediatr Hematol Oncol 2002;24:106-114.
14. Brown RT, Madan-Swain A, Walco GA, et al. Cognitive and academic late effects among children previously treated for acute lymphocytic leukemia receiving chemotherapy as CNS prophylaxis. J Pediatr Psychol. 1998;23:333-340.
15. Reddick WE, White H, Glass JO, et al. Developmental model relating white matter volume with neurocognitive deficits in pediatric brain tumor survivors. Cancer. 2003;97:2512-2519.
16. Reddick WE, Glass JO, Palmer SL, et al. Atypical white matter volume development in children following craniospinal irradiation. Neuro-Oncology. 2005;7:12-19.
17. Reddick WE, Glass JO, Helton KJ, Langston JW, XiongX, Pui C-H. Leukoencephalopathy prevalence in children treated for acute lymphoblastic leukemia with high-dose methotrexate. Am J Neuroradiol. 2005;2615:1263-1269.
18. Reddick WE, Glass JO, Helton KJ, Langston JW, Chin-Shang L, Pui C-H. A quantitative MRI assessment of leukoencephalopathy in children treated for acute lymphoblastic leukemia without irradiation. Am J Neuroradiol. 2005;26:2371-2377.
19. Paakko E, Harila-Saari A, Vanionpaa L, Himanen S, Pyhtinen J, Lanning M. White matter changes on MRI during treatment in children with acute lymphoblastic leukemia: correlation with neuropsychological findings. Med Pediatr Oncol. 2000;35:456-461.
20. Chu WCW, Chik KW, Chan YL, et al. White matter and cerebral metabolite changes in children undergoing treatment for acute lymphoblastic leukemia: longitudinal study with MR imaging and 1H MR spectroscopy 1. Radiology. 2003;229:659-669.
21. Mulhern RK, Khan RB, Kaplan S, et al. Short-term efficacy of methylphenidate: a randomized, double-blind, placebo-controlled trial among survivors of childhood cancer. J Clin Oncol. 2004;22:4743-4751.
22. The Psychological Corporation. The Wechsler Intelligence Test for Children-III, 3rd ed. New York: Harcourt, Brace, Jovanovich, Inc., 1997.
23. The Psychological Corporation. The Wechsler Adult Intelligence Scale-III. New York: Harcourt, Brace, Jovanovich, Inc., 1997.
24. Mulhern RK, Palmer SL, Reddick WE, et al. Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss. J Clin Oncol. 2001;19:472-479.
25. Sattler JM. Table L-13. In: Sattler JM. Assessment of children, revised and updated edition. San Diego: JM Sattler Publisher, Inc., 1992:1172.
26. Conners CK. The Conner's Continuous Performance Test. Toronto: Multi-Health Systems, 1995.
27. The Psychological Corporation. The Wechsler Individual Achievement Test. New York: Harcourt, Brace, Jovanovich, Inc., 1992.
28. Ostuni JL, Levin RL, Frank JA, DeCarli C. Correspondence of closest gradient voxels - a robust registration algorithm. J Magn Reson Imag. 1997;7:410-415.
29. Ji Q, Glass JO, Reddick WE. A fast entropy minimization algorithm for bias field correction in MR images. Miami: International Society for Magnetic Resonance in Medicine, 2005.
30. Glass JO, Ji Q, Glas LS, Reddick WE. Prediction of total cerebral tissue volumes in normal appearing brain from subsampled segmentation volumes. Magn Reson Imag. 2003;21:977-982.
31. Reddick WE, Glass JO, Cook EN, Elkin TD, Deaton R. Automated segmentation and classification of multispectral magnetic resonance images of brain using artificial neural networks. IEEE Trans Med Imag. 1997;16:911-918.
32. Ochs JJ. Neurotoxicity due to central nervous system therapy for childhood leukemia. Am J Pediatr Hematol Oncol. 1989;11:93-105.
33. Mennes M, Stiers P, Vandenbussche E, et al. Attention and information processing in survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only. Pediatr Blood Cancer. 2005;44:479-486.
34. Kandel ER, Schwartz JH, Jessell TM. Principles of neural science, 4th ed. New York: McGraw-Hill, 2000.
35. Connor JR, Menzies SL. Relationship of iron to oligodendrocytes and myelination. Glia. 1996;17:83-93.
36. Vymazal J, Brooks RA, Baumgarner C. The relation between brain iron and NMR relaxation times: an in vitro study. Magn Reson Med. 1996;35:56-61.
37. Smith B. Brain damage after intrathecal methotrexate. J Neurol Neurosurg Psychiatr. 1975;38:810-815.
38. Quinn CT, Griener JC, Bottiglieri T, Hyland K, Farrow A, Kamen BA. Elevation of homocysteine and excitatory amino acid neurotransmitters in the CSF of children who receive methotrexate for the treatment of cancer. J Clin Oncol. 1997;15:2800-2806.
39. van der Knaap MS, Valk J. Magnetic resonance of myelin, myelination and myelin disorders, 2nd ed. Heidelberg: Springer-Verlag, 1995.