3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice

Environmental and Molecular Mutagenesis

Volumn 47, Issue 1, 2006, Pages 67-70

  Wickliffe, Jeffrey K ^a   Galbert, L A ^a   Ammenheuser, M M ^a   Herring, S M ^a   Xie, J ^a   Masters III, O E ^b   Friedberg, E C ^c   Lloyd, R S ^d   Ward Jr , J B ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Benzo a pyrene; Butadiene; Epoxybutene; Hprt; Nucleotide excision repair; Xpc

Indexed keywords

1,2 EPOXY 3 BUTENE; 1,3 BUTADIENE; BENZO[A]PYRENE; DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; DOSE RESPONSE; EXCISION REPAIR; GENOME; GENOTOXICITY; IN VIVO STUDY; MOUSE; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; SOMATIC MUTATION; STATISTICAL SIGNIFICANCE;

ANIMALS; BENZO(A)PYRENE; DNA; DNA ADDUCTS; DNA REPAIR; DNA-BINDING PROTEINS; EPOXY COMPOUNDS; GENES, REPORTER; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICE; MICE, KNOCKOUT; MUTAGENS; MUTATION;

ANIMALIA;

EID: 32544448041     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.20169     Document Type: Article

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