Mild heat shock induces autophagic growth arrest, but not apoptosis in U251-MG and U87-MG human malignant glioma cells

Journal of Neuro-Oncology

Volumn 68, Issue 2, 2004, Pages 101-111

  Komata, Tadashi ^a   Kanzawa, Takao ^a,b   Nashimoto, Takeo ^a   Aoki, Hiroshi ^a   Endo, Shin ^a   Nameta, Masaaki ^a   Takahashi, Hideaki ^a   Yamamoto, Tadashi ^a   Kondo, Seiji ^b   Tanaka, Ryuichi ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Apoptosis; Autophagy; Cell cycle arrest; Electron micrography; Glioma; Hyperthermia

Indexed keywords

3 METHYLADENINE; ACRIDINE ORANGE; BAFILOMYCIN A1; 3-METHYLADENINE; ADENINE; DRUG DERIVATIVE; ENZYME INHIBITOR; MACROLIDE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL GROWTH; CELL VACUOLE; CONTROLLED STUDY; FLOW CYTOMETRY; GLIOBLASTOMA; GLIOMA CELL; GROWTH INHIBITION; HEAT SHOCK; HIGH TEMPERATURE; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; MITOCHONDRION; MITOSIS INHIBITION; PHAGOSOME; TRANSMISSION ELECTRON MICROSCOPY; BRAIN TUMOR; CELL CYCLE; CELL DIVISION; CELL ORGANELLE; DRUG EFFECT; GLIOMA; HEAT; PATHOLOGY; PHYSIOLOGY; THERMODYNAMICS; TUMOR CELL LINE; ULTRASTRUCTURE;

ADENINE; APOPTOSIS; AUTOPHAGY; BRAIN NEOPLASMS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; ENZYME INHIBITORS; GLIOMA; HEAT; HUMANS; MACROLIDES; ORGANELLES; THERMODYNAMICS;

EID: 3242885048     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NEON.0000027739.33842.6c     Document Type: Article

References (26)

1. Schoenberg BS: The epidemiology of central nervous system tumors. In: Walker MD (ed) Oncology of the Nervous System. Martinus Mijholf, Boston, 1983, pp 1-30
2. Mahaley MS Jr: National survey of patterns of care for brain-tumor patients. J Neurosurg 71: 826-836, 1989
3. Salcman M, Samaras GM: Hyperthermia for brain tumors: biophysical rationale. Neurosurgery 9: 327-335, 1981
4. Tanaka R, Kim CH, Yamada N, Saito Y: Radiofrequency hyperthermia for malignant brain tumors: preliminary results of clinical trials. Neurosurgery 21: 478-483, 1987
5. Uzuka T, Tanaka R, Takahashi H, Kakinuma K, Matsuda J, Kato K: Planning of hyperthermic treatment for malignant glioma using computer simulation. Int J Hyperthermia 17: 114-122, 2001
6. Takahashi H, Tanaka R, Uzuka T, Kon T, Aoki H, Endo S, Kano M, Igor G: Successful treatments of malignant glioma in the elderly by radiofrequency interstitial hyperthermia: a report of two cases. Jpn J Hyperthermic Oncol 18: 157-164, 2002
7. Page RC, Ricca GF, Dohan FC Jr: Hyperthermia for the treatment of brain tumors. Adv Exp Med Biol 267: 145-153, 1990
8. Quan KM, Watmough DJ, Mallard JR: Theoretical considerations in relation to the treatment of brain tumours by means of local hyperthermia generated by ultrasound fields. Eur J Surg Oncol 17: 454-465, 1991
9. Seegenschmiedt MH, Karlsson UL, Black P, Brady LW: Thermoradiotherapy for brain tumors: three cases of recurrent malignant astrocytoma and review of clinical experience. Am J Clin Oncol 18: 510-518, 1995
10. Menovsky T, Beek JF, van Gemert MJ, Roux FX, Brown SG: Interstitial laser thermotherapy in neurosurgery: a review. Acta Neurochir (Wien) 138: 1019-1026, 1996
11. Komata T, Kondo Y, Koga S, Ko SC, Chung LWK, Kondo S: Combination therapy of malignant glioma cells with 2-5A-antisense. telomerase. RNA and recombinant adenovirus p53. Gene. Ther 7: 2071-2079, 2000
12. Arvan P, Rudnick G, Castle JD: Osmotic properties and internal pH of isolated rat parotid secretory granules. J Biol Chem 259: 13567-13572, 1984
13. Mains RE, May V: The role of a low pH intracellular compartment in the processing, storage, and secretion of ACTH and endorphin. J Biol Chem 263: 7887-7894, 1988
14. Traganos F, Darzynkiewics Z: Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations. Methods Cell Biol 41: 185-194, 1994
15. Paglin S, Hollister T, Delohery T, Hackett N, McMahill M, Sphicas E, Domingo D, Yahalom J: A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 61: 439-444, 2001
16. Dunn WA Jr: Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J Cell Biol 110: 1935-1945, 1990
17. Knox SJ, Sutherland W, Goris ML: Correlation of tumor sensitivity to low-dose-rate irradiation with G2/M-phase block and other radiobiological parameters. Radiat Res 135: 24-31, 1993
18. Yamamoto A, Tagawa Y, Yoshimori T, Moriyama Y, Masaki R, Tashiro Y: Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct Funct 23: 33-42, 1998
19. Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P: Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 275: 992-998, 2000
20. Lenk SE, Dunn WA Jr, Trausch FS, Ciechanover A, Schwartz AL: Ubiquitin-activating enzyme, E1, is associated with maturation of autophagic vacuoles. J Cell Biol 118: 301-308, 1992
21. Reunanen H, Nykänen P: A cytochemical study on the effects of energy deprivation on autophagocytosis in Ehrlich ascites tumor cells. Histochemistry 90: 177-184, 1988
22. Reunanen H, Marttinen M, Hirsim⊣ki P: Effects of Griseofluvin and Nocodazole on the accumulation of autophagic vacuoles in Ehrlich asites tumor cells. Exp Mol Pathol 48: 97-102, 1988
23. Mortimore GE, Poso AR, Lardeux BR: Mechanism and regulation of protein degradation in liver. Diabetes Metab Rev 5: 49-70, 1989
24. Bursch W: The autophagosomal-lysosomal compartment in programmed cell death: review. Cell Death Diff 8: 569-581, 2001
25. Bursch W, Ellinger A, Gerner CH, Fröhwein U, Schulte-Hermann R: Programmed cell death (PCD): apoptosis, autophagic PCD, or others? Ann NY Acad Sci 926: 1-12, 2000
26. Kanzawa T, Kondo Y, Ito H, Kondo S, Germano IM: Induction of autophagic cell death in malignant glioma cells by arsenic trioxide. Cancer Res 63: 2103-2108, 2003