Expressions of junB and c-fos are enhanced in 4-nitroquinoline 1-oxide-induced rat tongue cancers

Pathology International

Volumn 54, Issue 1, 2004, Pages 35-40

  Ohyama, Masanobu ^a   Hirayama, Yoshikazu ^a   Tanuma, Jun Ichi ^a   Hirano, Masato ^a   Semba, Ichiro ^a   Shisa, Hayase ^b   Hiai, Hiroshi ^c   Sugihara, Kazumasa ^a   Kitano, Motoo ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b SAITAMA CANCER CENTER   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

4 nitroquinoline 1 oxide (4NQO); c fos; junB; Rat tongue cancer; Tscc1

Indexed keywords

4 NITROQUINOLINE 1 OXIDE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DYSPLASIA; EPITHELIUM; FEMALE; GENE EXPRESSION; GENE MUTATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; ONCOGENE; ONCOGENE C FOS; ONCOGENE JUNB; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TONGUE CANCER;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL NUCLEUS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, INBRED STRAINS; RNA, MESSENGER; RNA, NEOPLASM; TONGUE; TONGUE NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 3242804425     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2003.01587.x     Document Type: Article

References (33)

1. Kitano M, Hatano H, Shisa H. Strain difference of susceptibility to 4-nitroquinoline 1-oxide-induced tongue carcinoma in rats. Jpn J Cancer Res 1992; 83: 843-50.
2. Tanuma J, Shisa H, Hiai H et al. Quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in the rat. Cancer Res 1998; 58: 1660-4.
3. Tanuma J, Fujii K, Hirano M et al. Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat. Jpn J Cancer Res 2001; 92: 610-16.
4. Jochum W, Passegue E, Wagner EF. AP-1 in mouse development and tumorigenesis. Oncogene 2001; 20: 2401-12.
5. Shaulian E, Karin M. AP-1 in cell proliferation and survival. Oncogene 2001; 20: 2390-400.
6. Shaulian E, Karin M. AP-1 as a regulator of cell life and death. Nat Cell Biol 2002; 4: E131-6.
7. Ito T, Yamauchi M, Nishina M et al. Identification of SWI-SNF complex subunit BAF60a as a determinant of the transactivation potential of Fos/Jun dimers. J Biot Chem 2001; 276: 2852-7.
8. Pindborg JJ, Reichart PA, Smith CJ, van der Waal I, eds. Histological Typing of Cancer and Precancer of the Oral Mucosa, 2nd edn. Berlin: Springer-Verlag, 1997; 24-7.
9. Nakatsuka S, Nishiu M, Tomita Y et al. Enhanced expression of neuron-specific enolase (NSE) in pyothorax-associated lymphoma (PAL). Jpn J Cancer Res 2002; 93: 411-6.
10. Edelstein K, Beaule C, D'Abramo R, Amir S. Expression profiles of JunB and c-Fos proteins in the rat circadian cystems. Brain Res 2000; 870: 54-65.
11. Chiu R, Angel P, Karin M. Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun. Cell 1989; 59: 979-86.
12. Schutte J, Viallet J, Nau M, Segal S, Fedorko J, Minna J. jun-B inhibits and c-fos stimulates the transforming and transactivating activities of c-Jun. Cell 1989; 59: 987-97.
13. Finch S, Joseloff E, Bowden T. JunB negatively regulates AP-1 activity and cell proliferation of malignant mouse keratinocytes. J Cancer Res Clin Oncol 2002; 128: 3-10.
14. Andrecht S, Kolbus A, Hartenstein B, Angel P, Schorpp-Kistner M. Cell cycle promoting activity of junB through cyclin A activation. J Biol Chem 2002; 277: 35961-8.
15. Passegue E, Jochum W, Behrens A, Ricci R, Wagner EF. JunB can substitute for Jun in mouse development and cell proliferation. Nat Genet 2002; 30: 158-66.
16. Bamberger AM, Milde LK, Rossing E, Goemann C, Loning T. Expression pattern of the AP-1 family in endometrial cancer: correlations with cell cycle regulators. J Cancer Res Clin Oncol 2001; 127: 545-50.
17. Neyns B, Katesuwanasing, Vermeij J et al. Expression of the jun family of genes in human ovarian cancer and normal ovarian surface epithelium. Oncogene 1996; 12: 1247-57.
18. Wang H, Birkenbach M, Hart J. Expression of Jun family members in human colorectal adenocarcinoma. Carcinogenesis 2000; 21: 1313-17.
19. Robinson CM, Prime SS, Huntley S et al. Overexpression of JunB in undifferentiated malignant rat oral keratinocytes enhances the malignant phenotype in vitro without altering cellular differentiation. Int J Cancer 2001; 91: 625-30.
20. Yamit HA, Plaksin D, Eisenbach L. c-fos and c-jun overexpression in malignant cells reduces their tumorigenic and metastatic potential, and affects their MHC class I gene expression. Oncogene 1994; 9: 1065-79.
21. Takahashi S, Pearse AD, Marks R. Expression of c-fos proto-oncogene mRNA in non-melanoma skin cancer. J Dermatol Sci 1994; 7: 54-62.
22. Urabe A, Nakayama J, Taniguchi S, Terao H, Hori Y. Expression of the c-fos oncogene in chemically-induced mouse tumors and in human skin tumors. J Pathol 1992; 168: 281-6.
23. Hollander MC, Fornace AJ Jr. Induction of fos RNA by DNA-damaging agents. Cancer Res 1989; 49; 1687-92.
24. Li B, Tournier C, Davis RJ, Flavell RA. Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J 1999; 18: 420-32.
25. Miller C, Zhang M, He Y et al. Transcriptional induction of cyclooxygenase-2 gene by okadaic acid inhibition of phosphatase activity in human chondrocytes: co-stimulation of AP-1 and CRE nuclear binding proteins. J Cell Biochem 1998; 69: 392-413.
26. Schlingemann J, Hess J, Wrobel G et al. Profile of gene expression induced by the tumor promotor TPA in murine epithelial cells. Int J Cancer 2003; 104: 699-708.
27. Zaika A, Marchenko N, Moll UM. Cytoplasmic 'sequestered' wild type p53 protein is resistant to Mdm2-mediated degradation. J Biol Chem 1999; 274: 27474-80.
28. Chen Y, Chen CF, Riley DJ et al. Aberrant subcellular localization of BRCA1 in breast cancer. Science 1995; 270: 789-91.
29. Sheng H, Shao J, Williams CS et al. Nuclear translocation of β-catenin in hereditary and carcinogen-induced intestinal adenomas. Carcinogenesis 1998; 19: 543-9.
30. Ding W, Gao S, Scott RE. Senescence represses the nuclear localization of the serum response factor and differentiation regulates its nuclear localization with lineage specificity. J Cell Sci 2001; 114: 1011-18.
31. Treisman R. The SRE: a growth factor responsive transcriptional regulator. Semin Cancer Biol 1990; 1: 47-58.
32. HA induces autonomous papillomas in transgenic epidermis but not malignant conversion. Cancer Res 1993; 53: 5071-5.
33. Hulboy DL, Matrisian LM, Crawford HC. Loss of JunB activity enhances stromelysin 1 expression in a model of the epithelial-to-mesenchymal transition of mouse skin tumors. Mol Cell Biol 2001; 21: 5478-87.