A synthetic conjugate polysaccharide vaccine against haemophilus influenzae type b

Science

Volumn 305, Issue 5683, 2004, Pages 522-525

  Verez Bencomo, V ^a   Fernandez Santana V ^a   Hardy, Eugenio ^b   Toledo, Maria E ^c   Rodriguez, Maria C ^a   Heynngnezz, Lazaro ^b   Rodriguez, Arlene ^b   Baly, Alberto ^c   Herrera, Luis ^b   Izquierdo, Mabel ^b   Villar, Annette ^a   Valdés, Yury ^a   Cosme, Karelia ^b   Deler, Mercedes L ^a   Montane, Manuel ^b   Garcia, Ernesto ^a   Ramos, Alexis ^a   Aguilar, Aristides ^b   Medina, Ernesto ^b   Toraño, Gilda ^c   Sosa, Iván ^b   Hernandez, Ibis ^c   Martínez, Raydel ^c   Muzachio, Alexis ^b   Carmenates, Ania ^d   Costa, Lourdes ^b   Cardoso, Félix ^a   Campa, Concepción ^e   Diaz, Manuel ^c   Roy, René ^f   more..

^a UNIVERSITY OF HAVANA   (Cuba)

^b CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

^c INSTITUTO DE MEDICINA TROPICAL PEDRO KOURÍ   (Cuba)

^d Prov Ctr for Hyg and Epidemiology   (Cuba)

^e FINLAY INSTITUTE   (Cuba)

^f UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; BACTERIA; DISEASES; HEALTH CARE; SYNTHESIS (CHEMICAL); VACCINES;

INFECTIONS; PATHOGENS; PROPHYLAXIS;

POLYSACCHARIDES;

BACTERIAL POLYSACCHARIDE; CARBOHYDRATE ANTIGEN; GLYCOCONJUGATE; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; POLYSACCHARIDE VACCINE;

MEDICINE;

ANTIBODY TITER; ARTICLE; BACTERIAL INFECTION; CLINICAL TRIAL; CUBA; DRUG EFFICACY; DRUG SYNTHESIS; HAEMOPHILUS INFLUENZAE TYPE B; HUMAN; INFECTION PREVENTION; PRIORITY JOURNAL; VACCINE PRODUCTION;

ADULT; ANTIBODIES, BACTERIAL; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; GLYCOCONJUGATES; HAEMOPHILUS INFLUENZAE TYPE B; HAEMOPHILUS VACCINES; HUMANS; IMMUNIZATION SCHEDULE; IMMUNOGLOBULIN G; INFANT; POLYSACCHARIDES; POLYSACCHARIDES, BACTERIAL; TETANUS TOXOID; VACCINES, CONJUGATE;

BACTERIA (MICROORGANISMS); HAEMOPHILUS; HAEMOPHILUS INFLUENZAE; HAEMOPHILUS INFLUENZAE SEROTYPE B; NEGIBACTERIA;

EID: 3242797283     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1095209     Document Type: Article

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35. We would Like to thank the World Health Organization, the Pan-American Health Organization, and the following Cuban institutions: State Council, Ministers of Science Technology and Environment, and Ministry of Health. We are particularly thankful to J. M. Miyar, M. C. Santana, L. Yañez J. L. DiFabio, M. Beurret, and C. Jones for their fundamental contributions and the many laboratory assistants, medical doctors, and nurses that were involved in the project over the years. C. H. Fox critically reviewed the manuscript.