-
1
-
-
0343893748
-
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome
-
The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342:1301-8.
-
(2000)
N Engl J Med
, vol.342
, pp. 1301-1308
-
-
-
2
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane D, Sebille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002;288:862-71.
-
(2002)
JAMA
, vol.288
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
-
3
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344:699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
4
-
-
0035829852
-
Intensive insulin therapy in critically ill patients
-
van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients. N Engl J Med 2001;345:1359-67.
-
(2001)
N Engl J Med
, vol.345
, pp. 1359-1367
-
-
Van Den Berghe, G.1
Wouters, P.2
Weekers, F.3
-
5
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29:1303-10.
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
-
6
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis: The ACCP/SCCM Consensus Conference Committee-American College of Chest Physicians/Society of Critical Care Medicine
-
Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis: the ACCP/SCCM Consensus Conference Committee-American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992;101:1644-55.
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
-
7
-
-
0037389094
-
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
-
Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-6.
-
(2003)
Crit Care Med
, vol.31
, pp. 1250-1256
-
-
Levy, M.M.1
Fink, M.P.2
Marshall, J.C.3
-
8
-
-
0037309925
-
Pathogenesis of sepsis: New concepts and implications for future treatment
-
Bochud PY, Calandra T. Pathogenesis of sepsis: new concepts and implications for future treatment. BMJ 2003;326:262-6.
-
(2003)
BMJ
, vol.326
, pp. 262-266
-
-
Bochud, P.Y.1
Calandra, T.2
-
9
-
-
0027920980
-
Pathogenetic mechanisms of septic shock
-
Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med 1993;328:1471-7.
-
(1993)
N Engl J Med
, vol.328
, pp. 1471-1477
-
-
Parrillo, J.E.1
-
10
-
-
0034922171
-
Macrophage migration inhibitory factor and innate immune responses to bacterial infections
-
Froidevaux C, Roger T, Martin C, et al. Macrophage migration inhibitory factor and innate immune responses to bacterial infections. Crit Care Med 2001;29:S13-5.
-
(2001)
Crit Care Med
, vol.29
-
-
Froidevaux, C.1
Roger, T.2
Martin, C.3
-
11
-
-
0034834039
-
Low levels of protein C are associated with poor outcome in severe sepsis
-
Yan SB, Helterbrand JD, Hartman DL, et al. Low levels of protein C are associated with poor outcome in severe sepsis. Chest 2001;120:915-22.
-
(2001)
Chest
, vol.120
, pp. 915-922
-
-
Yan, S.B.1
Helterbrand, J.D.2
Hartman, D.L.3
-
12
-
-
0033584457
-
Disseminated intravascular coagulation
-
Levi M, Ten Cate H. Disseminated intravascular coagulation. N Engl J Med 1999;341:586-92.
-
(1999)
N Engl J Med
, vol.341
, pp. 586-592
-
-
Levi, M.1
Ten Cate, H.2
-
13
-
-
0029900294
-
Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein: The Soluble TNF Receptor Sepsis Study Group
-
Fisher CJ Jr, Agosti JM, Opal SM, et al. Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein: the Soluble TNF Receptor Sepsis Study Group. N Engl J Med 1996;334:1697-702.
-
(1996)
N Engl J Med
, vol.334
, pp. 1697-1702
-
-
Fisher Jr., C.J.1
Agosti, J.M.2
Opal, S.M.3
-
14
-
-
0034754254
-
Patterns of corticosteroid-binding globulin and the free cortisol index during septic shock and multitrauma
-
Beishuizen A, Thijs LG, Vermes I. Patterns of corticosteroid-binding globulin and the free cortisol index during septic shock and multitrauma. Intensive Care Med 2001;27:1584-91.
-
(2001)
Intensive Care Med
, vol.27
, pp. 1584-1591
-
-
Beishuizen, A.1
Thijs, L.G.2
Vermes, I.3
-
15
-
-
0035100693
-
Adrenal insufficiency during the late stage of polymicrobial sepsis
-
Koo DJ, Jackman D, Chaudry IH, Wang P. Adrenal insufficiency during the late stage of polymicrobial sepsis. Crit Care Med 2001;29:618-22.
-
(2001)
Crit Care Med
, vol.29
, pp. 618-622
-
-
Koo, D.J.1
Jackman, D.2
Chaudry, I.H.3
Wang, P.4
-
16
-
-
0031942028
-
Reversal of late septic shock with supraphysiologic doses of hydrocortisone
-
Bollaert PE, Charpentier C, Levy B, et al. Reversal of late septic shock with supraphysiologic doses of hydrocortisone. Crit Care Med 1998;26:645-50.
-
(1998)
Crit Care Med
, vol.26
, pp. 645-650
-
-
Bollaert, P.E.1
Charpentier, C.2
Levy, B.3
-
17
-
-
0029090390
-
Corticosteroid treatment for sepsis: A critical appraisal and meta-analysis of the literature
-
Cronin L, Cook DJ, Carlet J, et al. Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature. Crit Care Med 1995;23:1430-9.
-
(1995)
Crit Care Med
, vol.23
, pp. 1430-1439
-
-
Cronin, L.1
Cook, D.J.2
Carlet, J.3
-
18
-
-
0029036182
-
Steroid controversy in sepsis and septic shock: A meta-analysis
-
Lefering R, Neugebauer EA. Steroid controversy in sepsis and septic shock: a meta-analysis. Crit Care Med 1995;23:1294-303.
-
(1995)
Crit Care Med
, vol.23
, pp. 1294-1303
-
-
Lefering, R.1
Neugebauer, E.A.2
-
19
-
-
0342980285
-
A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin
-
Annane D, Sebille V, Troche G, et al. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA 2000;283:1038-45.
-
(2000)
JAMA
, vol.283
, pp. 1038-1045
-
-
Annane, D.1
Sebille, V.2
Troche, G.3
-
20
-
-
0033539018
-
Increased mortality associated with growth hormone treatment in critically ill adults
-
Takala J, Ruokonen E, Webster NR, et al. Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 1999;341:785-92.
-
(1999)
N Engl J Med
, vol.341
, pp. 785-792
-
-
Takala, J.1
Ruokonen, E.2
Webster, N.R.3
-
21
-
-
0142088505
-
Glucose control and mortality in critically ill patients
-
Finney SJ, Zekveld C, Elia A, Evans TW. Glucose control and mortality in critically ill patients. JAMA 2003;290:2041-7.
-
(2003)
JAMA
, vol.290
, pp. 2041-2047
-
-
Finney, S.J.1
Zekveld, C.2
Elia, A.3
Evans, T.W.4
-
22
-
-
0035880166
-
Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome
-
Eisner MD, Thompson T, Hudson LD, et al. Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;164:231-6.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 231-236
-
-
Eisner, M.D.1
Thompson, T.2
Hudson, L.D.3
-
23
-
-
0031834452
-
Multiple system organ failure: Is mechanical ventilation a contributing factor?
-
Slutsky AS, Tremblay LN. Multiple system organ failure: is mechanical ventilation a contributing factor? Am J Respir Crit Care Med 1998;157:1721-5.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1721-1725
-
-
Slutsky, A.S.1
Tremblay, L.N.2
-
24
-
-
0035110033
-
Protective effects of low tidal volume ventilation in a rabbit model of Pseudomonas aeruginosa-induced acute lung injury
-
Savel RH, Yao EC, Gropper MA. Protective effects of low tidal volume ventilation in a rabbit model of Pseudomonas aeruginosa-induced acute lung injury. Crit Care Med 2001;29:392-8.
-
(2001)
Crit Care Med
, vol.29
, pp. 392-398
-
-
Savel, R.H.1
Yao, E.C.2
Gropper, M.A.3
-
25
-
-
0032699215
-
Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia
-
Kurahashi K, Kajikawa O, Sawa T, et al. Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia. J Clin Invest 1999;104:743-50.
-
(1999)
J Clin Invest
, vol.104
, pp. 743-750
-
-
Kurahashi, K.1
Kajikawa, O.2
Sawa, T.3
-
27
-
-
0036892665
-
Meta-analysis of acute lung injury and acute respiratory distress syndrome trials
-
Brower RG, Matthay M, Schoenfeld D. Meta-analysis of acute lung injury and acute respiratory distress syndrome trials. Am J Respir Crit Care Med 2002;166:1515-7.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1515-1517
-
-
Brower, R.G.1
Matthay, M.2
Schoenfeld, D.3
-
29
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77.
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
-
30
-
-
0027427633
-
A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients
-
Boyd O, Grounds RM, Bennett ED. A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients. JAMA 1993;270:2699-707.
-
(1993)
JAMA
, vol.270
, pp. 2699-2707
-
-
Boyd, O.1
Grounds, R.M.2
Bennett, E.D.3
-
31
-
-
0033599760
-
Reducing the risk of major elective surgery: Randomised controlled trial of preoperative optimisation of oxygen delivery
-
Wilson J, Woods I, Fawcett J, et al. Reducing the risk of major elective surgery: randomised controlled trial of preoperative optimisation of oxygen delivery. BMJ 1999;318:1099-103.
-
(1999)
BMJ
, vol.318
, pp. 1099-1103
-
-
Wilson, J.1
Woods, I.2
Fawcett, J.3
-
32
-
-
0028275095
-
Elevation of systemic oxygen delivery in the treatment of critically ill patients
-
Hayes MA, Timmins AC, Yau EH, et al. Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med 1994;330:1717-22.
-
(1994)
N Engl J Med
, vol.330
, pp. 1717-1722
-
-
Hayes, M.A.1
Timmins, A.C.2
Yau, E.H.3
-
34
-
-
0343360868
-
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care: Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group
-
Hebert PC, Wells G, Blajchman MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care: Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 1999;340:409-17.
-
(1999)
N Engl J Med
, vol.340
, pp. 409-417
-
-
Hebert, P.C.1
Wells, G.2
Blajchman, M.A.3
-
35
-
-
0031590612
-
Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans
-
Smith OP, White B, Vaughan D, et al. Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans. Lancet 1997;350:1590-3.
-
(1997)
Lancet
, vol.350
, pp. 1590-1593
-
-
Smith, O.P.1
White, B.2
Vaughan, D.3
-
36
-
-
0033815369
-
The protein C pathway
-
Esmon C. The protein C pathway. Crit Care Med 2000;28:S44-8.
-
(2000)
Crit Care Med
, vol.28
-
-
Esmon, C.1
-
37
-
-
0035904368
-
Caring for the critically ill patient: High-dose antithrombin III in severe sepsis - A randomized controlled trial
-
Warren BL, Eid A, Singer P, et al. Caring for the critically ill patient: high-dose antithrombin III in severe sepsis-a randomized controlled trial. JAMA 2001;286:1869-78.
-
(2001)
JAMA
, vol.286
, pp. 1869-1878
-
-
Warren, B.L.1
Eid, A.2
Singer, P.3
-
38
-
-
0038690407
-
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial
-
Abraham E, Reinhart K, Opal S, et al. Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA 2003;290:238-47.
-
(2003)
JAMA
, vol.290
, pp. 238-247
-
-
Abraham, E.1
Reinhart, K.2
Opal, S.3
-
41
-
-
0037179680
-
An economic evaluation of activated protein C treatment for severe sepsis
-
Manns BJ, Lee H, Doig CJ, et al. An economic evaluation of activated protein C treatment for severe sepsis. N Engl J Med 2002;347:993-1000.
-
(2002)
N Engl J Med
, vol.347
, pp. 993-1000
-
-
Manns, B.J.1
Lee, H.2
Doig, C.J.3
-
42
-
-
0037032390
-
Physician staffing patterns and clinical outcomes in critically ill patients: A systematic review
-
Pronovost PJ, Angus DC, Dorman T, et al. Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review. JAMA 2002;288:2151-62.
-
(2002)
JAMA
, vol.288
, pp. 2151-2162
-
-
Pronovost, P.J.1
Angus, D.C.2
Dorman, T.3
|