Positive association between synapsin II and schizophrenia

Biological Psychiatry

Volumn 56, Issue 3, 2004, Pages 177-181

  Chen, Qi ^a   He, Guang ^a   Wang, Xiao Yan ^a   Chen, Qing Ying ^b   Liu, Xin Min ^a   Gu, Zhong Zhong ^d   Liu, Jie ^e   Li, Ke Qing ^e   Wang, Shi Ji ^f   Zhu, Shao Ming ^g   Feng, Guo Ying ^c   He, Lin ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c SHANGHAI MENTAL HEALTH CENTER   (China)

^d Huzhou Third People Hospital (ZZG)   (China)

^e KQL)   (China)

^f Fuyang Mental Hospital (SJW)   (China)

^g Jilin Institute of Mental Health   (China)

Author keywords

case control study; haplotype; schizophrenia; single nucleotide polymorphism; Synapsin II, association

Indexed keywords

SYNAPSIN II;

ADULT; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENE LOCATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA; SYNAPSINS;

EID: 3242777713     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2004.05.010     Document Type: Article

References (20)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed :1987;American Psychiatric Press, Washington, DC. revised
2. Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed :1988;215-271 Lawrence Erlbaum Associates, Hillsdale, New Jersey
3. Collins A., Morton N.E. Mapping a disease locus by allelic association. Proc Natl Acad Sci U S A. 95:1998;1741-1745
4. Erdfelder E., Faul F., Buchner A. G*Power A general power analysis program. Behav Res Methods Instrum Comput. 28:1996;1-11
5. Germer S., Holland M.J., Higuchi R. High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR. Genome Res. 10:2000;258-266
6. Greengard P., Valtorta F., Czernik A.J., Benfenati F. Synaptic vesicle phosphoproteins and regulation of synaptic function. Science. 259:1993;780-785
7. Greenwood T.A., Alexander M., Keck P.E., McElroy S., Sadovnick A.D., Remick R.A., et al. Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder. Am J Med Genet. 105:2001;145-151
8. Hyman S.E. The NIMH perspective Next steps in schizophrenia research. Biol Psychiatry. 47:2000;1-7
9. Kao H.T., Porton B., Czernik A.J., Feng J., Yiu G., Haring M., et al. A third member of the synapsin gene family. Proc Natl Acad Sci U S A. 95:1998;4667-4672
10. Karlin S., Chen C., Gentles A.J., Cleary M. Associations between human disease genes and overlapping gene groups and multiple amino acid runs. Proc Nat Acad Sci U S A. 99:2002;17008-17013
11. Mirnics K., Middleton F.A., Lewis D.A., Levitt P. Analysis of complex brain disorders with gene expression microarrays Schizophrenia as a disease of the synapse. Trends Neurosci. 24:2001;479-485
12. Mirnics K., Middleton F.A., Marquez A., Lewis D.A., Levitt P. Molecular characterization of clinical study schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron. 28:2000;53-67
13. Pulver A.E., Lasseter V.K., Kasch L., Wolyniec P., Nestadt G., Blouin J.-L., et al. Schizophrenia A genome scan targets chromosomes 3p and 8p as potential sites of susceptibility gene. Am J Med Genet. 60:1995;252-260
14. Reich D.E., Cargill M., Bolk S., Ireland J., Sabeti P.C., Richter D.J., et al. Linkage disequilibrium in the human genome. Nature. 411:2001;199-204
15. Sham P.C., Curtis D. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann Hum Genet. 59:1995;97-105
16. Shastry B.S. Schizophrenia A genetic perspective (review). Int J Mol Med. 9:2002;207-212
17. Tang J.X., Zhou J., Fan J.B., Li X.W., Shi Y.Y., Gu N.F., et al. Family-based association study of DTNBP1 in 6p22.3 and schizophrenia. Mol Psychiatry. 8:2003;717-718
18. Vawter M.P., Thatcher L., Usen N., Hyde T.M., Kleinman J.E., Freed W.J. Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Mol Psychiatry. 7:2002;571-578
19. Xie X. Testing linkage disequilibrium between a disease gene and marker loci. Am J Hum Genet. 53:1993;1107
20. Zapata C., Carollo C., Rodriguez S. Sampling variance and distribution of the D′ measure of overall gametic disequilibrium between multiallelic loci. Ann Hum Genet. 65:2001;395-406