CYP1A1, GSTM1, and GSTP1 genetic polymorphisms and urinary 1-hydroxypyrene excretion in non-occupationally exposed individuals

Cancer Epidemiology Biomarkers and Prevention

Volumn 9, Issue 10, 2000, Pages 1119-1122

  Nerurkar, Pratibha V ^a   Okinaka, Leila ^a   Aoki, Chris ^a   Seifried, Ann ^a   Lum Jones, Annette ^a   Wilkens, Lynne R ^a   Le Marchand, Loic ^a  

^a UNIVERSITY OF HAWAII CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXYPYRENE; BIOLOGICAL MARKER; CYTOCHROME P450 ISOENZYME; DNA; GLUTATHIONE TRANSFERASE; ISOENZYME; POLYCYCLIC AROMATIC HYDROCARBON; TOBACCO SMOKE;

ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; SMOKING; URINARY EXCRETION;

AGED; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A1; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE TRANSFERASE; HUMAN; ISOENZYMES; LIFE STYLE; LUNG NEOPLASMS; MALE; MIDDLE AGE; OCCUPATIONAL EXPOSURE; POLYCYCLIC HYDROCARBONS, AROMATIC; POLYMORPHISM (GENETICS); RISK FACTORS; SMOKING; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0033785547     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. The total human environmental exposure study (THEES) to benzo[a]pyrane: Comparison of the inhalation and food pathways
2. Assessment of carcinogenic risk from personal exposure to benzo[a]pyrene in the total human environmental exposure study (THEES)
3. Metabolism of polycyclic compounds: The metabolism of pyrene in rats and rabbits
4. Glutathione conjugation of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1
5. Identification of 1-hydroxypyrene glucuronide as a major metabolite in human urine by synchronous fluorescence spectroscopy and gas chromatography-mass spectrometry
6. Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in urine
7. 1-Hydroxypyrene in urine as a biological indicator of exposure to polycyclic aromatic hydrocarbons in several work environments
8. Polycyclic aromatic hydrocarbon-DNA adducts in white blood cell DNA and 1-hydroxypyrene in the urine from aluminum workers: Relation with job category and synergistic effect of smoking
9. Evaluation of urinary excretion of 1-hydroxypyrene and thioethers in workers exposed to bitumen fumes
10. Urinary excretion of 1-pyrenol in automotive repair workers
11. Interindividual differences in the concentration of 1-hydroxypyrene-glucuronide in urine and polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood cells after charbroiled beef consumption
12. An examination of the time course from human dietary exposure to polycyclic aromatic hydrocarbons to urinary elimination of 1-hydroxypyrene
13. High susceptibility to lung cancer analyzed in terms of combined genotypes of P450IAI and Mu-class glutathione S-transferase genes
14. Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population
15. Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggests cell type specificities to tobacco carcinogens
16. The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene
17. Urinary excretion of 1-hydroxypyrene as a marker for exposure to urban air levels of polycyclic aromatic hydrocarbons
18. Cytochrome P450 1A1 MspI polymorphism and urinary l-hydroxypyrene concentrations in coke-oven workers
19. Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer
20. Urinary 1-hydroxypyrene concentrations in coke oven workers
21. Cytochrome P450 CYP1A1 MspI polymorphism and lung cancer susceptibility
22. CYP1A1 genetic polymorphisms and in situ colorectal cancer
23. Human CYP1A1 gene: Cosegregation of the enzyme inducibility phenotype and an RFLP
24. Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans
25. Functional significance of different human CYP1A1 genotypes
26. Aromatic DNA adducts in foundry workers in relation to exposure, life style and CYP1A1 and glutathione transferase M1 genotype
27. Contribution of genetic and nutritional factors to DNA damage in heavy smokers
28. Glutathione S-transferase M1 and P1 genotypes and urinary excretion of 1-hydroxypyrene in coke oven workers