Acute and chronic effects of FR-149175, a β3-adrenergic receptor agonist, on energy expenditure in Zucker fatty rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 287, Issue 2 56-2, 2004, Pages

  Hatakeyama, Yoshifumi ^a,b   Sakata, Yoshihiko ^a   Takakura, Shoji ^a   Manda, Toshitaka ^a   Mutoh, Seitaro ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b Med Chemistry Research Laboratories   (Japan)

Author keywords

Desensitization; Hormone sensitive lipase; Oxygen consumption; Uncoupling protein 1

Indexed keywords

ANTIOBESITY AGENT; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; COMPLEMENTARY DNA; ETHYL [8 [2 (3 CHLOROPHENYL) 2 HYDROXYETHYLAMINO] 6,7,8,9 TETRAHYDRO 5H BENZOCYCLOHEPTON 2 YLOXY]ACETATE; FR 149175; GENOMIC DNA; MESSENGER RNA; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1;

ADIPOSE TISSUE; ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENERGY EXPENDITURE; GENE EXPRESSION; LIPOLYSIS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WEIGHT REDUCTION;

ACYL-COA DEHYDROGENASE, LONG-CHAIN; ANIMALS; BENZOCYCLOHEPTENES; CARNITINE O-PALMITOYLTRANSFERASE; CARRIER PROTEINS; CHOLESTEROL ESTERASE; ENERGY METABOLISM; GENE EXPRESSION; ION CHANNELS; LIPOLYSIS; MALE; MEMBRANE PROTEINS; MITOCHONDRIAL PROTEINS; OBESITY; OXYGEN CONSUMPTION; RATS; RATS, ZUCKER; RECEPTORS, ADRENERGIC, BETA-3;

EID: 3242751342     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00131.2004     Document Type: Article

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