IL-12p40-overexpressing immature dendritic cells induce T cell hyporesponsiveness in vitro but accelerate allograft rejection in vivo: Role of NK cell activation and interferon-gamma production

Immunology Letters

Volumn 94, Issue 3, 2004, Pages 191-199

  Sun, Wenji ^a   He, Xiaobo ^a   Guo, Zhenhong ^b   Wang, Quanxing ^b   Li, Xiaokang ^c   Rayner, Jane ^b   Zhang, Lihuang ^a   Wang, Jianli ^a   Cao, Xuetao ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c National Maritime Research Institute   (Japan)

Author keywords

Ad; adenovirus; antigen presenting cells; APC; CTL; cytotoxic T lymphocytes; DC; DC LacZ; DC p40; dendritic cells; HHT; IL 12p40 gene modified immature dendritic cells; imDC; immature dendritic cells; LacZ gene modified immature dendritic cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 23; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE EXACERBATION; DNA MODIFICATION; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

ANIMALS; DENDRITIC CELLS; DIMERIZATION; GRAFT REJECTION; HEART TRANSPLANTATION; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-23; INTERLEUKIN-23 SUBUNIT P19; INTERLEUKINS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MICE; PROTEIN SUBUNITS; T-LYMPHOCYTES; TRANSFECTION; TRANSPLANTATION, HOMOLOGOUS;

EID: 3242732123     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2004.05.001     Document Type: Article

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