Synthesis, characterization, and identification of N7-guanine adducts of isoprene monoepoxides in vitro

Chemical Research in Toxicology

Volumn 17, Issue 7, 2004, Pages 929-936

  Begemann, Petra ^a,c   Christova Georgieva, Nadia I ^a   Sangaiah, Ramiah ^a   Koc, Hasan ^a   Zhang, Daping ^b   Golding, Bernard T ^b   Gold, Avram ^a   Swenberg, James A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c ENVIRON INTERNATIONAL CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BUTADIENE; BIOLOGICAL MARKER; CARCINOGEN; DEOXYGUANOSINE; DNA; EPOXIDE; ETHYLENE OXIDE; GUANINE DERIVATIVE; ISOPRENE; ISOPRENE 1,2 OXIDE; ISOPRENE 3,4 OXIDE; N7 (1' HYDROXY 2' METHYL 3' BUTEN 2' YL)GUANINE; N7 (1' HYDROXY 3' METHYL 3' BUTEN 1' YL)GUANINE; N7 (2' HYDROXY 2' METHYL 3' BUTEN 1' YL)GUANINE; N7 (2' HYDROXY 3' METHYL 3' BUTEN 1' YL)GUANINE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DEGLYCOSYLATION; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MACROMOLECULE; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET SPECTROSCOPY;

BUTADIENES; DNA ADDUCTS; ENVIRONMENTAL POLLUTANTS; EPOXY COMPOUNDS; GUANINE; HEMITERPENES; PENTANES;

MAMMALIA;

EID: 3242720448     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0342565     Document Type: Article

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