Changed adhesion molecule profile of Ewing tumor cell lines and xenografts under the influence of ionizing radiation

Anticancer Research

Volumn 24, Issue 3 A, 2004, Pages 1637-1644

  Könemann, Stefan ^a   Malath, Johann ^a   Bölling, Tobias ^a   Kolkmeyer, Astrid ^a   Janke, Kirsten ^a   Riesenbeck, Dorothea ^a   Hesselmann, Stefan ^a   Nguyen, Tan Phu ^a   Diallo, Raihanatou ^b   Vormoor, Josef ^a   Willich, Normann ^a   Schuck, Andreas ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Adhesion molecules; Apoptosis; Ewing tumors; Ionizing radiation; Multiparametric flow cytometry

Indexed keywords

CD86 ANTIGEN; CELL ADHESION MOLECULE; CELL DNA; HERMES ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; LIPOCORTIN 5; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; NERVE CELL ADHESION MOLECULE; SYNEXIN; VERY LATE ACTIVATION ANTIGEN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL INTERACTION; CELL SUBPOPULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; EWING SARCOMA; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIZING RADIATION; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION DOSE; RADIATION RESPONSE; TUMOR CELL; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, CD; APOPTOSIS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; HUMANS; MICE; MICE, NUDE; SARCOMA, EWING'S; TIME FACTORS; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 3242696155     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Behrens J, Frixen U, Schipper J, Weidner M and Birchmeier W: Cell adhesion in invasion and metastasis. Semin Cell Biol 3: 169-178, 1992.
2. Zetter BR: Adhesion molecules in tumor metastasis. Sem Cancer Biol 4: 219-229, 1993.
3. Clezardin P: Recent insights into the role of integrins in cancer metastasis. Cell Mol Life Sci 54: 541-548, 1998.
4. Petruzzelli L, Takami M and Humes HD: Structure and function of cell adhesion molecules. Am J Med 106: 467-476, 1999.
5. Miele ME, Bennett F, Miller BE and Welch DR: Enhanced metastatic ability of TNF-a-treated malignant melanoma cells is reduced by Intercellular Adhesion Molecule-1 (ICAM-1, CD54) antisense oligonucleotides. Exp Cell Res 214: 231-241, 1994.
6. van Valen F, Hanenberg H and Jürgens H: Expression of functional very late antigen alpha 1, 2, 6 integrins on Ewing's sarcoma and primitive peripheral neuroectodermal tumor cells and modulation by interferon gamma and tumor necrosis factor alpha. Eur J Cancer 30A: 2119-2125, 1994.
7. Koga H, Naito S, Nakashima M, Hasegawa S, Watanabe T and Kumazawa J: A flow cytometric analysis of the expression of adhesion molecules on human renal cell carcinoma cells with different metastatic potentials. Eur Urol 31: 86-91, 1997.
8. Geertsen R, Zenklusen R, Kamarashev J, Burg G and Dummer R: Inverse regulation of neuronal cellular adhesion molecule (NCAM) by IFN-gamma in melanoma cell cultures established from CNS lesions. Int J Cancer 83: 135-140, 1999.
9. Gross N, Favre S, Beck D and Meyer M: Differentiation-related expression of adhesion molecules and receptors on human neuroblastoma tissues, cell lines and variants. Int J Cancer 52: 85-91, 1992.
10. Zhou YW, Komada Y, Inaba H, Deguchi T, Sugiyama K, Azuma E and Sakurai M: Functional significance of adhesion molecules in FAS-dependent apoptotic cell death induced by Interleukin-2-activated T cells. Immunol Invest 27: 309-322, 1998.
11. Kern PM, Keilholz L, Forster C, Hallmann R, Herrmann M and Seegenschmiedt MH: Low-dose radiotherapy selectively reduces adhesion of peripheral blood mononuclear cells to endothelium in vitro. Radiother Oncol 54: 273-282, 2000.
12. Kern PM, Keilholz L, Forster C, Stach C, Beyer TD, Gaipl US, Kalden JR, Hallmann R and Herrmann M: UVB-irradiated T-cells undergoing apoptosis lose L-selectin by metalloprotease-mediated shedding. Int J Radiat Biol 76: 1265-1271, 2000.
13. Hale AJ, Smith CA, Sutherland LC, Stoneman VE, Longthorne VL, Culhane AC and Williams GT: Apoptosis: molecular regulation of cell death. Eur J Bioch 236: 1-26, 1996.
14. Abend M and van Beuningen D: Bedeutung apoptotischer Prozesse für die Strahlentherapie. Teil I. Strahlenther Onkol 174: 156-166, 1998.
15. Abend M and van Beuningen D: Bedeutung apoptotischer Prozesse für die Strahlentherapie. Teil II. Strahlenther Onkol 174: 212-216, 1998.
16. Dahm-Daphi J: p53: Biology and role for cellular radiosensitivity. Strahlenther Onkol 176: 278-285, 2000.
17. Van Engeland M, Nieland LJW, Ramaekers FCS, Schutte B and Reutelingsperger CPM: Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31: 1-9, 1998.
18. Bedner E, Li X, Gorczyca W, Melamed MR and Darzynkiewicz Z: Analysis of apoptosis by laser scanning cytometry. Cytometry 35: 181-195, 1999.
19. Hong JH, Chiang CS, Campbell IL, Sun JR, Withers HR and McBride WH: Induction of acute phase gene expression by brain irradiation. Int J Radiat Oncol Biol Phys 33: 619-626, 1995.
20. Hallahan DE and Virudachalam S: Ionizing radiation mediates expression of cell adhesion molecules in distinct histological patterns within the lung. Cancer Res 57: 2096-2099, 1997.
21. Kawana A, Shioya S, Katoh H, Tsuji C, Tsuda M and Ohta Y: Expression of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 on alveolar macrophages in the acute stage of radiation-induced lung injury in rats. Radiat Res 147: 431-436, 1997.
22. Quarmby S, Hunter RD and Kumar S: Irradiation induced expression of CD31, ICAM-1 and VCAM-1 in human microvascular endothelial cells. Anticancer Res 20: 3375-3382, 2000.
23. Santin AD, Rose GS, Hiserodt JC, Fruehauf J, Eck LM, Garcia RI, Schranz V, Disaia PJ, Pecorelli S and Granger GA: Effects of cytokines combined with high-dose gamma irradiation on the expression of major histocompatibility complex molecules and intercellular adhesion molecule-1 in human ovarian cancers. Int J Cancer 65: 688-694, 1996.
24. Hareyama M, Imai K, Oouchi A, Takahashi H, Hinoda Y, Tsujisaki M, Adachi M, Shonai T, Sakata K and Morita K: The effect of radiation on the expression of intercellular adhesion molecule-1 of human adenocarcinoma cells. Int J Radiat Oncol Biol Phys 40: 691-696, 1998.
25. Meineke V, Gilbertz KP, Schilperoort K, Cordes N, Sendler A, Moede T and van Beuningen D: Ionizing radiation modulates cell surface integrin expression and adhesion of COLO-320 cells to collagen and fibronectin in vitro. Strahlenther Onkol 178: 709-714, 2002.
26. Cordes N, Blaese MA, Meineke V and Van Beuningen D: Ionizing radiation induces up-regulation of functional beta1-integrin in human lung tumour cell lines in vitro. Int J Radiat Biol 78: 347-357, 2002.
27. Hollander Z and Loken MR: Simultaneous analysis of DNA content and surface antigens in human bone marrow. Cytometry 9: 485-490, 1988.
28. Brons PP, Pennings AH, Haanen C, Wessels HM and Boezeman JB: Simultaneous measurement of DNA content and cell-surface immunofluorescence of human bone marrow cells using a single laser flow cytometer. Cytometry 11: 837-844, 1990.
29. Schmid I, Uittenbogaart CH and Giorgi JV: A gentle fixation and permeabilization method for combined cell surface and intracellular staining with improved precision in DNA quantification. Cytometry 12: 279-285, 1990.
30. Stokke T, Holte H, Erikstein B, Davies CL, Funderud S and Stehen HB: Simultaneous assessment of chromatin structure, DNA content, and antigen expression by dual wavelength excitation flow cytometry. Cytometry 12: 172-178, 1991.
31. Corver WE, Bonsing BA, Abeln ECA, Vlak-Theil PM, Cornelisse CJ and Fleuren GJ: One-tube triple staining method for flow cytometric analysis of DNA ploidy and phenotypic heterogeneity of human solid tumors using single laser excitation. Cytometry 25: 358-366, 1996.
32. Könemann S, Schuck A, Malath J, Rupek T, Horn K, Baumann M, Vormoor J, Rübe C and Willich N: Cell heterogeneity and subpopulations in solid tumors characterized by simultaneous immunophenotyping and DNA content analysis. Cytometry 41: 172-177, 2000.
33. Bacso Z and Eliason JF: Measurement of DNA damage associated with apoptosis by laser scanning cytometry. Cytometry 45: 180-186, 2001.
34. Rasola A and Geuna M: A flow cytometry assay simultaneously detects independent apoptotic parameters. Cytometry 45: 151-157, 2001.
35. Ambros IM, Ambros PF, Strehl S, Kovar H, Gadner H and Salabendzer-Kuntschick M: MIC2 is a specific marker of Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration. Cancer 67: 1886-1893, 1991.
36. van Valen F, Winkelmann W, Burdach S, Gobel U and Jürgens H: Interferon gamma and tumor necrosis factor induce a synergistic antiproliferative response in human Ewing sarcoma cells in vivo. J Cancer Res Clin Oncol 119: 615-621, 1993.
37. Floersheim GL: Comparative growth of human tumors in pharmacologically immunosuppressed, immune-deprived, cyclosporin-A treated and nude mice. Eur J Cancer Clin Oncol 18: 589-594, 1982.
38. Phillips RA, Jewett MAS and Gallie BL: Growth of human tumors in immune-deficient scid mice and nude mice. Curr Top Microbiol Immun 152: 259-263, 1989.
39. Simmons D, Makgoba MW and Seed B: ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM. Nature 331: 624-627, 1988.
40. Cunningham BA, Hemperly JJ, Murray BA, Prediger EA, Brackenbury R and Edelman GM: Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science 236: 799-806, 1987.
41. Gardner LJ, Polski JM, Fallon R and Dunphy CH: Identification of CD56 and CD57 by flow cytometry in Ewing's sarcoma or primitive neuroectodermal tumor, Virch Arch 433: 35-40, 1998.
42. Yamanaka R, Tanaka R and Yoshida S: Effects of irradiation on the expression of the adhesion molecules (NCAM, ICAM-1) by glioma cell lines. Neurol Med Chir 33: 749-752, 1993.
43. Larson RS, Corbi AL, Berman L and Springer T: Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily. J Cell Biol 108: 703-712, 1989.
44. Tedder TF, Isaacs CM, Ernst TJ, Demetri GD, Adler DA and Disteche CM: Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins. J Exp Med 170: 123-133, 1989.