Synthesis and antiproliferative activity of 3-aryl-2-[1H(2H)-benzotriazol- 1(2)-yl]acrylonitriles variously substituted: Part 4

Farmaco

Volumn 59, Issue 8, 2004, Pages 637-644

  Carta, Antonio ^a   Palomba, Michele ^a   Boatto, Gianpiero ^a   Busonera, Bernardetta ^b   Murreddu, Marta ^b   Loddo, Roberta ^b  

^a UNIVERSITY OF SASSARI   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

3 Aryl 2 (1H(2H) benzotriazol 1(2) yl)acrylonitriles; Antiproliferative activity; Antitubercular screening; SAR

Indexed keywords

2 (2H BENZOTRIAZOL 2 YL) 3 (2 IODOPHENYL)ACRYLONITRILE; 2 (2H BENZOTRIAZOL 2 YL) 3 (3 FLUOROPHENYL)ACRYLONITRILE; 2 (5 TRIFLUOROMETHYL 1H BENZOTRIAZOL 1 YL) 3 (3 NITROPHENYL)ACRYLONITRILE; 2 (5 TRIFLUOROMETHYL 1H BENZOTRIAZOL 1 YL) 3 (3,4 METHYLENEDIOXYPHENYL) ACRYLONITRILE; 2 (5 TRIFLUOROMETHYL 1H BENZOTRIAZOL 1 YL) 3 (4 METHOXYPHENYL) ACRYLONITRILE; 2 (5 TRIFLUOROMETHYL 2H BENZOTRIAZOL 2 YL) 3 (3 NITROPHENYL)ACRYLONITRILE; 2 (5 TRIFLUOROMETHYL 2H BENZOTRIAZOL 2 YL) 3 (3,4 METHYLENEDIOXYPHENYL) ACRYLONITRILE; 2 (5 TRIFLUOROMETHYL 2H BENZOTRIAZOL 2 YL) 3 (4 METHOXYPHENYL) ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 (3 NITROPHENYL)ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 (3 TRIFLUOROMETHYLPHENYL) ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 (3,4 METHYLENEDIOXYPHENYL) ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 (4 BROMOPHENYL)ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 (4 CHLOROPHENYL)ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 (4 METHOXYPHENYL)ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 (4 METHYLPHENYL)ACRYLONITRILE; 2 (5,6 DIMETHYL 1H BENZOTRIAZOL 1 YL) 3 PHENYLACRYLONITRILE; 2 (5,6 DIMETHYL 2H BENZOTRIAZOL 2 YL) 3 (3,4 DIMETHOXYPHENYL)ACRYLONITRILE; 2 (6 TRIFLUOROMETHYL 1H BENZOTRIAZOL 1 YL) 3 (3 NITROPHENYL)ACRYLONITRILE; 2 1H(2H) BENZOTRIAZOL 1(2) ACRYLONITRILE; ACRYLONITRILE; ANTINEOPLASTIC AGENT; ETOPOSIDE; MERCAPTOPURINE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MYCOBACTERIUM ABSCESSUS; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID TUMOR; SUBSTITUTION REACTION;

ACRYLONITRILE; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; ANTITUBERCULAR AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 3242693295     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2004.03.004     Document Type: Article

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