Synthesis and antitubercular activity of 3-aryl substituted-2-(1H(2H) benzotriazol-1(2)-yl)acrylonitriles

European Journal of Medicinal Chemistry

Volumn 35, Issue 5, 2000, Pages 535-543

  Sanna, Paolo ^a   Carta, Antonio ^a   Nikookar, Mohammad E Rahbar ^a  

^a Dipartimento Farmaco Chimico Tossicologico   (Italy)

Author keywords

3 aryl substituted 2 (1H(2H) benzotriazol 1(2) yl)acrylonitriles; Antimycobacterial activity; Knoevenagel condensation

Indexed keywords

ACRYLONITRILE; BENZOTRIAZOLE DERIVATIVE; CLARITHROMYCIN; RIFAMPICIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL VIRULENCE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MYCOBACTERIUM AVIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET SPECTROSCOPY;

EID: 0034091543     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(00)00144-6     Document Type: Article

References (27)

1. Billo N.E. Global aspects of tuberculosis. Gangadharam P.R.J, Jenkins P.A. Mycobacteria II Chemotherapy. 1998;1-14 Chapman & Hall, NY.
2. Raviglione M.C., Snider D.E., Kochi A. J. Am. Med. Assoc. 273:1995;220-226.
3. Kochi A. Tubercle. 72:1991;1-6.
4. Lounis N., Ji B., Truffot-Pernot C., Grosset J. Antimicrob. Agents Chemother. 41:1997;607-610.
5. Grinev A.N., Lyubchanskaya V.M., Uretskaya G.Y., Vlasova T.F., Pershin G.N., Bogdanova N.S., et al. Khim.-Farm. Zh. 87:1977;78-81.
6. Waisser K, Kunes J, Odlerova Z. Collect. Czech. Chem. Commun. 56:1991;2978-2985.
7. Sidoova E., Odlerova Z., Waisser K., Czech. CS 275, 212; Chem. Abs. 119 (1993) 271151y.
8. Sidoova E., Odlerova Z., Waisser K., Czech. CS 275, 212; Chem. Abs. 119 (1993) 271151y.
9. Ambrosoli G., Ciuti M.P., Menozzi M.G., Mingiardi M.R. Boll. Chim. Farm. 109:1970;251-258.
10. Sawlewicz J., Milczarska B., Manowska W. Pol. J. Pharmacol. Pharm. 27:1975;187-201.
11. Milczarska B, Sawlewicz J, Manowska W. Pol. J. Pharmacol. Pharm. 28:1976;521-528.
12. Bukowski L. Pol. J. Pharmacol. Pharm. 38:1986;91-98.
13. Sanna P, Paglietti G. Farmaco. 44:1989;609-618.
14. Sanna P., Nuvole A., Sequi P.A., Paglietti G. Heterocycles. 36:1993;259-280.
15. Sanna P., Sequi P.A., Piras S., Paglietti G. Heterocycles. 41:1995;2459-2474.
16. Sanna P., Carta A., Paglietti G. Heterocycles. 51:1999;2171-2181.
17. Nuvole A., Sanna P., Paglietti G., Juliano C., Zanetti S., Cappucinelli P. Farmaco. 44:1989;619-632.
18. Sanna P., Carta A., Paglietti G., Zanetti S., Fadda G. Farmaco. 47:1992;1001-1019.
19. Paglietti G., Sanna P., Carta A., Sparatore F., Vazzana I., Peana A., Satta M. Farmaco. 49:1994;693-702.
20. Sanna P., Sequi P.A., Paglietti G. Farmaco. 50:1995;47-54.
21. Sparatore F., Pagani F. Farmaco. 19:1964;55-75.
22. Danan A., Charon D., Kirkiacharian S., Bories C., Loiseau P.M. Farmaco. 52:1997;227-229.
23. Kingsbury C.A., Draney D., Sopchik A., Rissler W., Durban D. J. Org. Chem. 41:1976;3863-3868.
24. Vogeli U., von Philipsborn W., Nagarajan K., Nair M.D. Helv. Chim. Acta. 61:1978;607-617.
25. Paglietti G., Sparatore F. Ann. Chim. (Rome). 62:1972;128-143.
26. Middlebrook G., Regginardo Z., Tigerit W.D. Am. Rev. Respir. Dis. 115:1977;1066-1069.
27. Collins L., Franzblau S.G. Antimicrob. Agents Chemother. 41:1997;1004-1009.