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Volumn 1059, Issue , 2005, Pages 41-55

Sulindac sulfone is most effective in modulating β-catenin-mediated transcription in cells with mutant APC

Author keywords

APC; Colon; Sulindac sulfone; catenin

Indexed keywords

APC PROTEIN; AZOXYMETHANE; BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PROTEASOME INHIBITOR; SULINDAC SULFIDE; SULINDAC SULFONE;

EID: 32244442175     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1339.020     Document Type: Conference Paper
Times cited : (17)

References (37)
  • 1
    • 0026726952 scopus 로고
    • Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas
    • COTTRELL, S., D. BICKNELL, L. KAKLAMANIS, et al. 1992. Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas. Lancet 340: 626-630.
    • (1992) Lancet , vol.340 , pp. 626-630
    • Cottrell, S.1    Bicknell, D.2    Kaklamanis, L.3
  • 2
    • 0031557898 scopus 로고    scopus 로고
    • The adenomatous polyposis coli (APC) tumor suppressor
    • POLAKIS, P. 1997. The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta 1332: F127-F147.
    • (1997) Biochim. Biophys. Acta , vol.1332
    • Polakis, P.1
  • 3
    • 0027738023 scopus 로고
    • Association of the APC gene product with β-catenin
    • RUBINFELD, B., B. SOUZA, I. ALBERT, et al. 1993. Association of the APC gene product with β-catenin. Science 262: 1731-1734.
    • (1993) Science , vol.262 , pp. 1731-1734
    • Rubinfeld, B.1    Souza, B.2    Albert, I.3
  • 4
    • 0027756014 scopus 로고
    • Association of the APC tumor suppressor protein with catenins
    • SU, L.K., B. VOGELSTEIN & K.W. KINZLER. 1993. Association of the APC tumor suppressor protein with catenins. Science 262: 1734-1737.
    • (1993) Science , vol.262 , pp. 1734-1737
    • Su, L.K.1    Vogelstein, B.2    Kinzler, K.W.3
  • 5
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/- colon carcinoma
    • KORINEK, V., N. BARKER, P.J. MORIN, et al. 1997. Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/- colon carcinoma. Science 275: 1784-1787.
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3
  • 6
    • 0033545845 scopus 로고    scopus 로고
    • The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
    • SHTUTMAN, M., J. ZHURINSKY, I. SIMCHA, et al. 1999. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway. Proc. Natl. Acad. Sci. USA 96: 5522-5527.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5522-5527
    • Shtutman, M.1    Zhurinsky, J.2    Simcha, I.3
  • 7
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • HE, T.-C., A.B. SPARKS, C. RAGO, et al. 1998. Identification of c-MYC as a target of the APC pathway. Science 281: 1509-1512.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.-C.1    Sparks, A.B.2    Rago, C.3
  • 8
    • 0033615352 scopus 로고    scopus 로고
    • PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • HE, T.C., T.A. CHAN, B. VOGELSTEIN, et al. 1999. PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99: 335-345.
    • (1999) Cell , vol.99 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3
  • 9
    • 0029920515 scopus 로고    scopus 로고
    • Alteration of β-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients
    • INOMATA, M., A. OCHIAI, S. AKIMOTO, et al. 1996. Alteration of β-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients. Cancer Res. 56: 2213-2217.
    • (1996) Cancer Res. , vol.56 , pp. 2213-2217
    • Inomata, M.1    Ochiai, A.2    Akimoto, S.3
  • 10
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
    • SPARKS, A.B., P.J. MORIN, B. VOGELSTEIN, et al. 1998. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res. 58: 1130-1134.
    • (1998) Cancer Res. , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3
  • 11
    • 0024211723 scopus 로고
    • A protective effect of sulindac against chemically-induced primary colonic tumors in mice
    • MOORGHEN, M., P. INCE, K.J. FINNEY, et al. 1988. A protective effect of sulindac against chemically-induced primary colonic tumors in mice. J. Pathol. 156: 341-347.
    • (1988) J. Pathol. , vol.156 , pp. 341-347
    • Moorghen, M.1    Ince, P.2    Finney, K.J.3
  • 12
    • 0026075136 scopus 로고
    • Sulindac inhibits the rate of growth and appearance of colon tumors in the rat
    • SKINNER, S.A., A.G. PENNEY & P.E. O'BRIEN. 1991. Sulindac inhibits the rate of growth and appearance of colon tumors in the rat. Arch. Surg. 126: 1094-1096.
    • (1991) Arch. Surg. , vol.126 , pp. 1094-1096
    • Skinner, S.A.1    Penney, A.G.2    O'Brien, P.E.3
  • 13
    • 0025834849 scopus 로고
    • Sulindac causes regression of rectal polyps in familial adenomatous polyposis
    • LABAYLE, D., D. FISCHER, P. VIELH, et al. 1991. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology 101: 635-639.
    • (1991) Gastroenterology , vol.101 , pp. 635-639
    • Labayle, D.1    Fischer, D.2    Vielh, P.3
  • 14
    • 0027197062 scopus 로고
    • Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
    • GIARDIELLO, P.M., S.R. HAMILTON, A.J. KRUSH, et al. 1993. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N. Engl. J. Med. 328: 1313-1316.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1313-1316
    • Giardiello, P.M.1    Hamilton, S.R.2    Krush, A.J.3
  • 15
    • 0030968757 scopus 로고    scopus 로고
    • Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction
    • PIAZZA, G.A., A.K. RAHM, T.S. FINN, et al. 1997. Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction. Cancer Res. 57: 2452-2459.
    • (1997) Cancer Res. , vol.57 , pp. 2452-2459
    • Piazza, G.A.1    Rahm, A.K.2    Finn, T.S.3
  • 16
    • 0030747817 scopus 로고    scopus 로고
    • Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels
    • PIAZZA, G.A., D.S. ALBERTS, L.J. HIXSON, et al. 1997. Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. Cancer Res. 57: 2909-2915.
    • (1997) Cancer Res. , vol.57 , pp. 2909-2915
    • Piazza, G.A.1    Alberts, D.S.2    Hixson, L.J.3
  • 17
    • 0033565252 scopus 로고    scopus 로고
    • Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process
    • REDDY, B.S., T. KAWAMORI, R.A. LUBET, et al. 1999. Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process. Cancer Res. 59: 3387-3391.
    • (1999) Cancer Res. , vol.59 , pp. 3387-3391
    • Reddy, B.S.1    Kawamori, T.2    Lubet, R.A.3
  • 18
    • 0033956565 scopus 로고    scopus 로고
    • Phase I trial of exisulind (sulindac sulfone, FGN-1) as a chemopreventive agent in patients with familial adenomatous polyposis
    • VAN STOLK, R., G. STONER, W.L. HAYTON, et al. 2000. Phase I trial of exisulind (sulindac sulfone, FGN-1) as a chemopreventive agent in patients with familial adenomatous polyposis. Clin. Cancer Res. 6: 78-89.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 78-89
    • Van Stolk, R.1    Stoner, G.2    Hayton, W.L.3
  • 19
    • 0030014026 scopus 로고    scopus 로고
    • Sulindac increases the expression of APC mRNA in malignant colonic epithelial cells: An in vitro study
    • SCHNITZLER, M., T. DWIGHT & B.C. ROBINSON. 1996. Sulindac increases the expression of APC mRNA in malignant colonic epithelial cells: an in vitro study. Gut 38: 707-713.
    • (1996) Gut , vol.38 , pp. 707-713
    • Schnitzler, M.1    Dwight, T.2    Robinson, B.C.3
  • 21
    • 0030923587 scopus 로고    scopus 로고
    • β-catenin mutations in cell lines established from human colorectal cancers
    • ILYAS, M., I.P.M. TOMLINSON, A. ROWAN, et al. 1997. β-catenin mutations in cell lines established from human colorectal cancers. Proc. Natl. Acad. Sci. USA 94: 10330-10334.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10330-10334
    • Ilyas, M.1    Tomlinson, I.P.M.2    Rowan, A.3
  • 22
    • 0028335192 scopus 로고
    • Antiproliferative effect of nonsteroidal antiinflammatory drugs against human colon cancer cells
    • HIXSON, L., D.S. ALBERTS, M. KRUTZSCH, et al. 1994. Antiproliferative effect of nonsteroidal antiinflammatory drugs against human colon cancer cells. Cancer Epidemiol. Biomarkers Prev. 3: 433-437.
    • (1994) Cancer Epidemiol. Biomarkers Prev. , vol.3 , pp. 433-437
    • Hixson, L.1    Alberts, D.S.2    Krutzsch, M.3
  • 23
    • 0029451275 scopus 로고
    • Do non-steroidal anti-inflammatory drugs (NSAIDs) exert their colon cancer chemoprevention activities through inhibition of colonic mucosal prostaglandin synthetase?
    • ALBERTS, D.S., L. HIXSON, D. AHNEN, et al. 1995. Do non-steroidal anti-inflammatory drugs (NSAIDs) exert their colon cancer chemoprevention activities through inhibition of colonic mucosal prostaglandin synthetase? J. Cell. Biochem. Suppl. 22: 18-23.
    • (1995) J. Cell. Biochem. Suppl. , vol.22 , pp. 18-23
    • Alberts, D.S.1    Hixson, L.2    Ahnen, D.3
  • 24
    • 0033213814 scopus 로고    scopus 로고
    • Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines
    • LIM, J.T., G.A. PIAZZA, E.K. HAN, et al. 1999. Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines. Biochem. Pharmacol. 58: 1097-1107.
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 1097-1107
    • Lim, J.T.1    Piazza, G.A.2    Han, E.K.3
  • 25
    • 0001674959 scopus 로고    scopus 로고
    • Induction of apoptosis by sulindac metabolites involves a p53 and bcl-2 independent mechanism and does not require cell cycle arrest
    • PIAZZA, G., A. RAHM, R. PAMUKCU, et al. 1996. Induction of apoptosis by sulindac metabolites involves a p53 and bcl-2 independent mechanism and does not require cell cycle arrest. Gastroenterology 110: A577.
    • (1996) Gastroenterology , vol.110
    • Piazza, G.1    Rahm, A.2    Pamukcu, R.3
  • 26
    • 0036830654 scopus 로고    scopus 로고
    • Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation
    • Li, H., L. LIU, M.L. DAVID, et al. 2002. Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation. Biochem. Pharmacol. 64: 1325-1336.
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 1325-1336
    • Li, H.1    Liu, L.2    David, M.L.3
  • 27
    • 0034234978 scopus 로고    scopus 로고
    • Exisulind induction of apoptosis involves guanosine 3′,5′- cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin
    • THOMPSON, W.J., G.A. PIAZZA, H. LI, et al. 2000. Exisulind induction of apoptosis involves guanosine 3′,5′-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin. Cancer Res. 60: 3338-3342.
    • (2000) Cancer Res. , vol.60 , pp. 3338-3342
    • Thompson, W.J.1    Piazza, G.A.2    Li, H.3
  • 28
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
    • RUBINFELD, B., I. ALBERT, E. PORFIRI, et al. 1996. Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly. Science 272: 1023-1026.
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3
  • 29
    • 0028893391 scopus 로고
    • Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line
    • SHIOZAKI, H., T. KADOWAKI, Y. DOKI, et al. 1995. Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line. Br. J. Cancer. 71: 250-258.
    • (1995) Br. J. Cancer. , vol.71 , pp. 250-258
    • Shiozaki, H.1    Kadowaki, T.2    Doki, Y.3
  • 30
    • 0028001677 scopus 로고
    • B-2 gene product associates with catenins in human cancer cells
    • OCHIAI, A., S. AKIMOTO, Y. KANAI, et al. 1994. c-erbB-2 gene product associates with catenins in human cancer cells. Biochem. Biophys. Res. Commun. 205: 73-78.
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 73-78
    • Ochiai, A.1    Akimoto, S.2    Kanai, Y.3
  • 31
    • 0030949463 scopus 로고    scopus 로고
    • Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
    • MORIN, P.J., A.B. SPARKS, V. KORINEK, et al. 1997. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 275: 1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3
  • 32
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization
    • DIEHL, J.A., M. CHENG, M.F. ROUSSEL, et al. 1998. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 12: 3499-3511.
    • (1998) Genes Dev. , vol.12 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3
  • 33
    • 0034721853 scopus 로고    scopus 로고
    • Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells
    • SHAO, J., H. SHENG, H. INOUE, et al. 2000. Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J. Biol. Chem. 275: 33951-33956.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33951-33956
    • Shao, J.1    Sheng, H.2    Inoue, H.3
  • 34
    • 0033139531 scopus 로고    scopus 로고
    • Sulindac sulfide, but not sulindac sulfone, inhibits colorectal cancer growth
    • WILLIAMS, C.S., A.P. GOLDMAN, H. SHENG, et al. 1999. Sulindac sulfide, but not sulindac sulfone, inhibits colorectal cancer growth. Neoplasia 1: 170-176.
    • (1999) Neoplasia , vol.1 , pp. 170-176
    • Williams, C.S.1    Goldman, A.P.2    Sheng, H.3
  • 35
    • 0030118622 scopus 로고    scopus 로고
    • APC gene mutations in human prostate cancer
    • WATANABE, M., H. KAKIUCHI, H. KATO, et al. 1996. APC gene mutations in human prostate cancer. Jpn. J. Clin. Oncol. 26: 77-81.
    • (1996) Jpn. J. Clin. Oncol. , vol.26 , pp. 77-81
    • Watanabe, M.1    Kakiuchi, H.2    Kato, H.3
  • 36
    • 2642673582 scopus 로고    scopus 로고
    • β-catenin mutations in human prostate cancer
    • VOELLER, H.J., C.I. TRUICA & E.P. GELMANN. 1998. β-Catenin mutations in human prostate cancer. Cancer Res. 58: 2520-2523.
    • (1998) Cancer Res. , vol.58 , pp. 2520-2523
    • Voeller, H.J.1    Truica, C.I.2    Gelmann, E.P.3
  • 37
    • 0031595691 scopus 로고    scopus 로고
    • The APCI1307K allele and breast cancer risk
    • REDSTON, M., K.L. NATHANSON, Z.Q. YUAN, et al. 1998. The APCI1307K allele and breast cancer risk. Nat. Genet. 20: 13-14.
    • (1998) Nat. Genet. , vol.20 , pp. 13-14
    • Redston, M.1    Nathanson, K.L.2    Yuan, Z.Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.