MCI-186 (edaravone), a free radical scavenger, attenuates ischemia-reperfusion injury and activation of phospholipase A2 in an isolated rat lung model after 18 h of cold preservation

European Journal of Cardio-thoracic Surgery

Volumn 29, Issue 3, 2006, Pages 304-311

  Reyes, Yury A Bellido ^a   Shimoyama, Takehiko ^a   Akamatsu, Hideki ^a   Sunamori, Makoto ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Edaravone; Ischemia reperfusion; Lung; Phospholipase A2

Indexed keywords

4 ETHYNYL 3 [3 FLUORO 4 [(2 METHYL 1H IMIDAZO[4,5 C]PYRIDIN 1 YL)METHYL]BENZOYL] N,N DIMETHYL 1H INDOLE 1 CARBOXAMIDE; HYDROLASE; LEUKOTRIENE B4; MYELOPEROXIDASE; NORPHENAZONE; PHOSPHOLIPASE A2; SCAVENGER; SODIUM CHLORIDE; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOCYTE ACTIVATING FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; ISCHEMIA; LIPID PEROXIDATION; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; LUNG TRANSPLANTATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REPERFUSION INJURY; THORACOTOMY;

ANIMALS; ANTIPYRINE; BRONCHOALVEOLAR LAVAGE FLUID; COLD ISCHEMIA; DISEASE MODELS, ANIMAL; EDEMA; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; LIPID PEROXIDATION; LUNG; MALE; ORGAN CULTURE TECHNIQUES; ORGAN PRESERVATION; OXIDATIVE STRESS; OXYGEN; PHOSPHOLIPASES A; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 32144457044     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2005.12.005     Document Type: Article

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