Inhibition of cellular proliferation by diterpenes, topoisomerase II inhibitor

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 6, 2006, Pages 2048-2051

  Miyata, Shohei ^a   Wang, Li Yan ^b   Yoshida, Chisato ^a   Kitanaka, Susumu ^a  

^a NIHON UNIVERSITY   (Japan)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Diterpene; Euphorbia kansui; Inhibition of cell proliferation; Inhibition of topoisomerase II; Xenopus embryo cell

Indexed keywords

20 O (2',4' DECADIENOYL)INGENOL; 20 O(DECANOYL)INGENOL; 3 O (2',4' DECADIENOYL) 20 ACETYLINGENOL; 3 O (2',4' DECADIENOYL)INGENOL; 3 O 5 ACETATE INGENOL; 3 O BENZOYL 20 DEOXYINGENOL; 3 O(2',4' DECADIENOYL) 20 DEOXYINGENOL; 5 O (2',4' DECADIENOYL)INGENOL; 5 O BENZOYL 20 DEOXYINGENOL; DITERPENE; DNA TOPOISOMERASE INHIBITOR; EUPHORBIA EXTRACT; INGENOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLASTULA; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; DRUG STRUCTURE; EUPHORBIA; FEMALE; MALE; NONHUMAN; PLANT ROOT; XENOPUS LAEVIS;

ANIMALS; CELL PROLIFERATION; DITERPENES; DNA TOPOISOMERASES, TYPE II; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; EMBRYO, NONMAMMALIAN; ENZYME INHIBITORS; EUPHORBIA; FEMALE; MALE; XENOPUS LAEVIS;

ANIMALIA; EUPHORBIA; EUPHORBIA KANSUI; XENOPUS LAEVIS;

EID: 32044444576     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.10.059     Document Type: Article

References (15)

1. S. Miyata, L.Y. Wang, L.Y. Wang, X.S. Yao, and S. Kitanaka Cell Biol. Int. 28 2004 179
2. L.Y. Wang, N.L. Wang, X.S. Yao, S. Miyata, and S. Kitanaka J. Nat. Prod. 66 2003 630
3. L.Y. Wang, N.L. Wang, X.S. Yao, S. Miyata, and S. Kitanaka J. Nat. Prod. 65 2002 1246
4. T. Okouchi, T. Abe, S. Araki, S. Arai, T. Iida, L.Y. Wang, S. Kitanaka, and S. Miyata Bioorg. Med. Chem. 13 2005 3847
5. R. Ishida, M. Sato, T. Narita, K.R. Utsumi, T. Nishimoto, T. Morita, H. Nagata, and T. Andoh J. Cell Biol. 126 1994 1341
6. H. Anderson, and M. Roberge Cell Growth Differ. 7 1996 83
7. J.C. Wang Annu. Rev. Biochem. 54 1985 665
8. M. Gellert Annu. Rev. Biochem. 50 1981 879
9. L.F. Liu Annu. Rev. Biochem. 58 1989 351
10. T. Andoh, and R. Ishida Biochim. Biophys. Acta 1400 1998 1155
11. A.K. Larsen, A.E. Escargueil, and A. Skladanowski Prog. Cell Cycle Res. 5 2003 295
12. K.R. Hande Biochim. Biophys. Acta 1400 1998 173
13. S.H. Kaufmann Biochim. Biophys. Acta 1400 1998 195
14. C. Perez, N.E. Vilaboa, L. Garcia-Bermejo, E. de Blas, A.M. Creighton, and P. Aller J. Cell Sci. 110 1997 337
15. L.H. Jensen, K.C. Nitiss, A. Rose, J. Dong, J. Zhou, T. Hu, N. Osheroff, P.B. Jensen, M. Sehested, and J.L. Nitiss J. Biol. Chem. 275 2000 2137