Posttraumatic vasospasm: The epidemiology, severity, and time course of an underestimated phenomenon: A prospective study performed in 299 patients

Journal of Neurosurgery

Volumn 103, Issue 5, 2005, Pages 812-824

  Oertel, Matthias ^b   Boscardin, W John ^b   Obrist, Walter D ^b   Glenn, Thomas C ^a   McArthur, David L ^b   Gravori, Tooraj ^b   Jae, Hong Lee ^b   Martin, Neil A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Cerebral blood flow; Head injury; Time course; Transcranial Doppler ultrasonography

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BASILAR ARTERY; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN VASOSPASM; CONTROLLED STUDY; DATA ANALYSIS; DISEASE COURSE; DISEASE SEVERITY; DOPPLER ECHOGRAPHY; FEMALE; GLASGOW COMA SCALE; HEMODYNAMIC MONITORING; HOSPITAL ADMISSION; HUMAN; INCIDENCE; INTENSIVE CARE UNIT; MALE; MIDDLE CEREBRAL ARTERY; ONSET AGE; POSTTRAUMATIC COMPLICATION; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SAMPLING; SCORING SYSTEM;

ADULT; ANTERIOR CEREBRAL ARTERY; CEREBROVASCULAR CIRCULATION; CRANIOCEREBRAL TRAUMA; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; POSTERIOR CEREBRAL ARTERY; PREDICTIVE VALUE OF TESTS; PREVALENCE; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SUBARACHNOID HEMORRHAGE; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; VASOSPASM, INTRACRANIAL;

EID: 32044443210     PISSN: 00223085     EISSN: 00223085     Source Type: Journal    
DOI: 10.3171/jns.2005.103.5.0812     Document Type: Article

References (78)

1. Aaslid R, Huber P, Nornes H: Evaluation of cerebrovascular spasm with transcranial Doppler ultrasound. J Neurosurg 60:37-41, 1984
2. Aaslid R, Markwalder TM, Nornes H: Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 57:769-774, 1982
3. Alexander M, Rinsky B, Thomas K, Martin NA: Characteristics of vertebral-basilar transcranial Doppler studies in trauma patients. Stroke 24:520, 1993 (Abstract)
4. Allen GS, Ahn HS, Preziosi TJ, Battye R, Boone SC, Boone SC, et al: Cerebral arterial spasm-a controlled trial of nimodipine in patients with subarachnoid hemorrhage. N Engl J Med 308:619-624, 1983
5. Anonymous: A multicenter trial of the efficacy of nimodipine on outcome after severe head injury. The European Study Group On Nimodipine in Severe Head Injury. J Neurosurg 80:797-804, 1994
6. Arutiunov AI, Baron MA, Majorova NA: The role of mechanical factors in the pathogenesis of short-term and prolonged spasm of the cerebral arteries. J Neurosurg 40:459-472, 1974
7. Awad IA, Carter LP, Spetzler RF, Medina M, Williams FC Jr: Clinical vasospasm after subarachnoid hemorrhage: response to hypervolemic hemodilution and arterial hypertension. Stroke 18:365-372, 1987
8. Barker FG II, Ogilvy CS: Efficacy of prophylactic nimodipine for delayed ischemic deficit after subarachnoid hemorrhage: a metaanalysis. J Neurosurg 84:405-414, 1996
9. Bullock R, Chesnut RM, Clifton G, Ghajar J, Marion DW, Narayan RK, et al: Guidelines for the management of severe head injury. Brain Trauma Foundation. Eur J Emer Med 3:109-127, 1996
10. Chan KH, Dearden NM, Miller JD: The significance of posttraumatic increase in cerebral blood flow velocity: a transcranial Doppler ultrasound study. Neurosurgery 30:697-700, 1992
11. Chan KH, Dearden NM, Miller JD, Midgley S, Piper IR: Transcranial Doppler waveform differences in hyperemic and nonhyperemic patients after severe head injury. Surg Neurol 38:433-436, 1992
12. Chan KH, Miller JD, Dearden NM: Intracranial blood flow velocity after head injury: relationship to severity of injury, time, neurological status and outcome. J Neurol Neurosurg Psychiatry 55:787-791, 1992
13. Chui M, Battista AF, Kricheff II: Vasospasm of the vertebrobasilar system in cases of ruptured intracranial aneurysm. Neurosurgery 12:542-548, 1983
14. Columella F, Delzanno GB, Gaist G, Piazza G: Angiography in traumatic cerebral lacerations with special regard to some less common aspects. Acta Radiol 1:239-247, 1963
15. Compton JS, Teddy PJ: Cerebral arterial vasospasm following severe head injury: a transcranial Doppler study. Br J Neurosurg 1:435-439, 1987
16. Devlin JW, Coplin WM, Murry KR, Rengachary SS, Wilson RF: Nimodipine-induced acute hypoxemia: case report. Neurosurgery 47:1243-1247, 2000
17. Dorsch N, Zurynski Y: Post-traumatic vasospasm influences head injury outcome. Can J Neurol Sci 20 (Suppl 1):S28, 1993 (Abstract)
18. Eisenberg HM, Gary HE Jr, Aldrich EF, Saydjari C, Turner B, Foulkes MA, et al: Initial CT findings in 753 patients with severe head injury. A report from the NIH Traumatic Coma Data Bank. J Neurosurg 73:688-698, 1990
19. Firlik AD, Kaufmann AM, Jungreis CA, Yonas H: Effect of transluminal angioplasty on cerebral blood flow in the management of symptomatic vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg 86:830-839, 1997
20. Firlik KS, Kaufmann AM, Firlik AD, Jungreis CA, Yonas H: Intra-arterial papaverine for the treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Surg Neurol 51:66-74, 1999
21. Fisher CM, Kistler JP, Davis JM: Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery 6:1-9, 1980
22. Gabrielsen TO, Greitz T: Normal size of the internal carotid, middle cerebral and anterior cerebral arteries. Acta Radiol Diagn (Stockh) 10:1-10, 1970
23. Glenn TC, Obrist WD, Vespa P, Lee SJ, Hovda DA, Martin NA: Onset of cerebral vasospasm following acute brain injury is associated with diminished cerebral metabolic rate of oxygen. J Cereb Blood Flow Metab 23 (Suppl 1):394, 2003 (Abstract)
24. Gosling RG, Dunbar G, King DH, Newman DL, Side CD, Woodcock JP, et al: The quantitative analysis of occlusive peripheral arterial disease by a non-intrusive ultrasonic technique. Angiology 22:52-55, 1971
25. Greene KA, Marciano FF, Harrington TR: Posttraumatic vasospasm. J Neurosurg 87:134-136, 1997
26. Grolimund P, Weber M, Seiler RW, Reulen HJ: Time course of cerebral vasospasm after severe head injury. Lancet 1:1173, 1988
27. Grubb RL Jr, Raichle ME, Eichling JO, Gado MH: Effects of subarachnoid hemorrhage on cerebral blood volume, blood flow, and oxygen utilization in humans. J Neurosurg 46:446-453, 1977
28. Hadani M, Bruk B, Ram Z, Knoller N, Bass A: Transiently increased basilar artery flow velocity following severe head injury: a time course transcranial Doppler study. J Neurotrauma 14:629-636, 1997
29. Harders A, Kakarieka A, Braakman R, German tSAH Study Group: Traumatic subarachnoid hemorrhage and its treatment with nimodipine. J Neurosurg 85:82-89, 1996
30. Harders AG, Gilsbach JM: Time course of blood velocity changes related to vasospasm in the circle of Willis measured by transcranial Doppler ultrasound. J Neurosurg 66:718-728, 1987
31. Horn P, Vajkoczy P, Bauhuf C, Munch E, Poeckler-Schoeniger C, Schmiedek P: Quantitative regional cerebral blood flow measurement techniques improve noninvasive detection of cerebrovascular vasospasm after aneurysmal subarachnoid hemorrhage. Cerebrovasc Dis 12:197-202, 2001
32. Jakobsen M: Role of initial brain ischemia in subarachnoid hemorrhage following aneurysm rupture. A pathophysiological survey. Acta Neurol Scand Suppl 141:1-33, 1992
33. Jakobsen M, Enevoldsen E, Bjerre P: Cerebral blood flow and metabolism following subarachnoid haemorrhage: cerebral oxygen uptake and global blood flow during the acute period in patients with SAH. Acta Neurol Scand 82:174-182, 1990
34. Jakobsen M, Enevoldsen E, Dalager T: Spasm index in subarachnoid haemorrhage: consequences of vasospasm upon cerebral blood flow and oxygen extraction. Acta Neurol Scand 82:311-320, 1990
35. Jenkins LW, Moszynski K, Lyeth BG, Lewelt W, DeWitt DS, Allen A, et al: Increased vulnerability of the mildly traumatized rat brain to cerebral ischemia: the use of controlled secondary ischemia as a research tool to identify common or different mechanisms contributing to mechanical and ischemic brain injury. Brain Res 477:211-224, 1989
36. Kakarieka A, Braakman R, Schakel EH: Clinical significance of the finding of subarachnoid blood on CT scan after head injury. Acta Neurochir 129:1-5, 1994
37. Kakarieka A, Schakel EH, Fritze J: Clinical experiences with nimodipine in cerebral ischemia. J Neural Transm Suppl 43:13-21, 1994
38. Kassell NF, Helm G, Simmons N, Phillips CD, Cail WS: Treatment of cerebral vasospasm with intra-arterial papaverine. J Neurosurg 77:848-852, 1992
39. Kassell NF, Peerless SJ, Durward QJ, Beck DW, Drake CG, Adams HP: Treatment of ischemic deficits from vasospasm with intravascular volume expansion and induced arterial hypertension. Neurosurgery 11:337-343, 1982
40. Kassell NF, Sasaki T, Colohan AR, Nazar G: Cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Stroke 16:562-572, 1985
41. Kelly DF, Kordestani RK, Martin NA, Nguyen T, Hovda DA, Bergsneider M, et al: Hyperemia following traumatic brain injury: relationship to intracranial hypertension and outcome. J Neurosurg 85:762-771, 1996
42. Kistler JP, Crowell RM, Davis KR, Heros R, Ojemann RG, Zervas T, et al: The relation of cerebral vasospasm to the extent and location of subarachnoid blood visualized by CT scan: a prospective study. Neurology 33:424-436, 1983
43. Laumer R, Steinmeier R, Gönner F, Vogtmann T, Priem R, Fahlbusch R: Cerebral hemodynamics in subarachnoid hemorrhage evaluated by transcranial Doppler sonography. Part 1. Reliability of flow velocities in clinical management. Neurosurgery 33:1-9, 1993
44. Lee JH, Martin NA, Alsina G, McArthur DL, Zaucha K, Hovda DA, et al: Hemodynamically significant cerebral vasospasm and outcome after head injury: a prospective study. J Neurosurg 87:221-233, 1997
45. Leeds NE, Reid ND, Rosen LM: Angiographic changes in cerebral contusions and intracerebral hematomas. Acta Radiol Diagn (Stockh) 5:320-327, 1966
46. Lindegaard KF, Nornes H, Bakke SJ, Sorteberg W, Nakstad P: Cerebral vasospasm diagnosis by means of angiography and blood velocity measurements. Acta Neurochir (Wien) 100:12-24, 1989
47. Marshall LF, Bruce DA, Bruno L, Langfitt TW: Vertebrobasilar spasm: a significant cause of neurological deficit in head injury. J Neurosurg 48:560-564, 1978
48. Martin NA, Alsina G, Kordestani R, Lee JH: The Simonsen Cerebrograph Cortexplorer. Neurosurgery 39:1059-1061, 1996
49. Martin NA, Doberstein C, Alexander M, Khanna R, Benalcazar H, Alsina G, et al: Posttraumatic cerebral arterial spasm. J Neurotrauma 12:897-901, 1995
50. Martin NA, Doberstein C, Zane C, Caron MJ, Thomas K, Becker DP: Posttraumatic cerebral arterial spasm: transcranial Doppler ultrasound, cerebral blood flow, and angiographic findings. J Neurosurg 77:575-583, 1992
51. Martin NA, Patwardhan RV, Alexander MJ, Africk CZ, Lee JH, Shalmon E, et al: Characterization of cerebral hemodynamic phases following severe head trauma: hypoperfusion, hyperemia, and vasospasm. J Neurosurg 87:9-19, 1997
52. Mascia L, Fedorko L, terBrugge K, Filippini C, Pizzio M, Ranieri VM, et al: The accuracy of transcranial Doppler to detect vasospasm in patients with aneurysmal subarachnoid hemorrhage. Intensive Care Med 29:1088-1094, 2003
53. Mattioli C, Beretta L, Gerevini S, Veglia F, Citerio G, Cormio M, et al: Traumatic subarachnoid hemorrhage on the computerized tomography scan obtained at admission: a multicenter assessment of the accuracy of diagnosis and the potential impact on patient outcome. J Neurosurg 98:37-42, 2003
54. Morgan MK, Jonker B, Finfer S, Harrington T, Dorsch NW: Aggressive management of aneurysmal subarachnoid haemorrhage based on a papaverine angioplasty protocol. J Clin Neurosci 7:305-308, 2000
55. Morris GF, Bullock R, Marshall SB, Marmarou A, Maas A, The Selfotel Investigators, et al: Failure of the competitive N-methyl-D-aspartate antagonist Selfotel (CGS 19755) in the treatment of severe head injury: results of two Phase III clinical trials. The Selfotel Investigators. J Neurosurg 91:737-743, 1999
56. Newell DW, Eskridge JM, Mayberg MR, Grady MS, Winn HR: Angioplasty for the treatment of symptomatic vasospasm following subarachnoid hemorrhage. J Neurosurg 71:654-660, 1989
57. Obrist WD, Langfitt TW, Jaggi JL, Cruz J, Gennarelli TA: Cerebral blood flow and metabolism in comatose patients with acute head injury. Relationship to intracranial hypertension. J Neurosurg 61:241-253, 1984
58. Obrist WD, Marion DW, Aggarwal S, Kerr ME: Acute changes in human cerebral blood flow and metabolism following severe brain trauma: effect of hypothermia. J Cereb Blood Flow Metab 21 (Suppl 1):105, 2001 (Abstract)
59. Obrist WD, Thompson HK Jr, Wang HS, Wilkinson WE: Regional cerebral blood flow estimated by 133-xenon inhalation. Stroke 6:245-256, 1975
60. Obrist WD, Wilkinson WE: Regional cerebral blood flow measurement in humans by xenon-133 clearance. Cerebrovasc Brain Metab Rev 2:283-327, 1990
61. Oskouian RJ Jr, Martin NA, Lee JH, Glenn TC, Guthrie D, Gonzalez NR, et al: Multimodal quantitation of the effects of endovascular therapy for vasospasm on cerebral blood flow, transcranial Doppler ultrasonographic velocities, and cerebral artery diameters. Neurosurgery 51:31-43, 2002
62. Pott W, Kaps M: Zerebrale vasospasmen nach traumatischer subarachnoidal blutung. Nervenarzt 62:493-495, 1991
63. Rabinstein AA, Friedman JA, Weigand SD, McClelland RL, Fulgham JR, Manno EM, et al: Predictors of cerebral infarction in aneurysmal subarachnoid hemorrhage. Stroke 35:1862-1866, 2004
64. Radhakrishnan D, Menon DK: Haemodynamic effects of intravenous nimodipine following aneurysmal subarachnoid haemorrhage: implications for monitoring. Anaesthesia 52:489-491, 1997
65. Rice JA, Wu CO: Nonparametric mixed effects models for unequally sampled noisy curves. Biometrics 57:253-259, 2001
66. Romner B, Bellner J, Kongstad P, Sjoholm H: Elevated transcranial Doppler flow velocities after severe head injury: cerebral vasospasm or hyperemia? J Neurosurg 85:90-97, 1996
67. Servadei F, Murray GD, Teasdale GM, Dearden M, Iannotti F, Lapierre F, et al: Traumatic subarachnoid hemorrhage: demographic and clinical study of 750 patients from the European brain injury consortium survey of head injuries. Neurosurgery 50:261-269, 2002
68. Soustiel JF, Bruk B, Shik B, Hadani M, Feinsod M: Transcranial Doppler in vertebrobasilar vasospasm after subarachnoid hemorrhage. Neurosurgery 43:282-293, 1998
69. Suarez JI, Qureshi AI, Yahia AB, Parekh PD, Tamargo RJ, Williams MA, et al: Symptomatic vasospasm diagnosis after subarachnoid hemorrhage: evaluation of transcranial Doppler ultrasound and cerebral angiography as related to compromised vascular distribution. Crit Care Med 30:1348-1355, 2002
70. Suwanwela C, Suwanwela N: Intracranial arterial narrowing and spasm in acute head injury. J Neurosurg 36:314-323, 1972
71. Symon L: An experimental study of traumatic cerebral vascular spasm. J Neurol Neurosurg Psychiatry 30:497-505, 1967
72. Taneda M, Kataoka K, Akai F, Asai T, Sakata I: Traumatic subarachnoid hemorrhage as a predictable indicator of delayed ischemic symptoms. J Neurosurg 84:762-768, 1996
73. Voldby B, Petersen OF, Buhl M, Jakobsen P, Ostergaard R: Reversal of cerebral arterial spasm by intrathecal administration of a calcium antagonist (nimodipine). Acta Neurochir 70:243-254, 1984
74. Wadworth AN, McTavish D: Nimodipine. A review of its pharmacological properties, and therapeutic efficacy in cerebral disorders. Drugs Aging 2:262-286, 1992
75. Weber M, Grolimund P, Seiler RW: Evaluation of posttraumatic cerebral blood flow velocities by transcranial Doppler ultrasonography. Neurosurgery 27:106-112, 1990
76. Weir B, Grace M, Hansen J, Rothberg C: Time course of vasospasm in man. J Neurosurg 48:173-178, 1978
77. Zubkov AY, Pilkington AS, Bernanke DH, Parent AD, Zhang J: Posttraumatic cerebral vasospasm: clinical and morphological presentations. J Neurotrauma 16:763-770, 1999
78. Zurynski YA, Dorsch NW, Pearson I: Incidence and effects of increased cerebral blood flow velocity after severe head injury: a transcranial Doppler ultrasound study. I. Prediction of post-traumatic vasospasm and hyperemia. J Neurol Sci 134:33-40, 1995