Use of a chemical probe to increase safety for human volunteers in toxicokinetic studies

Risk Analysis

Volumn 25, Issue 6, 2005, Pages 1559-1571

  Brochot, Céline ^a   Bois, Frédéric Y ^a  

^a INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

Author keywords

1,3 butadiene; Chemical probe; Human exposures; PBPK modeling

Indexed keywords

ACCIDENT PREVENTION; AIR; CONCENTRATION (PROCESS); PROBES; RATE CONSTANTS; TOXIC MATERIALS;

1,3-BUTADIENE; CHEMICAL PROBE; HUMAN EXPOSURES; PBPK MODELING;

RISKS;

1,3 BUTADIENE; ISOFLURANE; PESTICIDE;

POLLUTION EXPOSURE; SAFETY;

ARTICLE; BAYES THEOREM; COMPARTMENT MODEL; CONCENTRATION RESPONSE; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; EXPIRED AIR; EXPOSURE; HUMAN; HUMAN EXPERIMENT; INHALATION; MATHEMATICAL MODEL; METABOLIC RATE; NORMAL HUMAN; PARTITION COEFFICIENT; SAFETY; SPECIES DIFFERENCE; TOXICOKINETICS; VOLUNTEER;

AIR POLLUTANTS; BAYES THEOREM; BUTADIENES; HUMANS; ISOFLURANE; MODELS, BIOLOGICAL; MOLECULAR PROBES; RISK ASSESSMENT; SAFETY; TOXICOLOGY;

EID: 31944431830     PISSN: 02724332     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1539-6924.2005.00682.x     Document Type: Article

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