Transactivation of the ICAM-1 gene by CD30 in Hodgkin's lymphoma

International Journal of Cancer

Volumn 118, Issue 5, 2006, Pages 1098-1107

  Uchihara, Jun Nosuke ^a   Matsuda, Takehiro ^a   Okudaira, Taeko ^a   Ishikawa, Chie ^a   Masuda, Masato ^a   Horie, Ryouichi ^b   Watanabe, Toshiki ^c   Ohta, Takao ^a   Takasu, Nobuyuki ^a   Mori, Naoki ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

CD30; Hodgkin's lymphoma; ICAM 1; NF B; TRAF

Indexed keywords

CD30 ANTIGEN; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 8; LIGAND; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PROTEIN P50; PROTEIN P52; RNA; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR REL; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR;

ARTICLE; CELL INTERACTION; CELL NUCLEUS; CONTROLLED STUDY; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HODGKIN DISEASE; HUMAN; HUMAN CELL; LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REED STERNBERG CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION;

ANTIGENS, CD; ANTIGENS, CD30; CD30 LIGAND; CELL LINE; GENE EXPRESSION REGULATION, NEOPLASTIC; HODGKIN DISEASE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; LYMPHOCYTES; NF-KAPPA B; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TUMOR NECROSIS FACTORS;

EID: 31844452688     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.21427     Document Type: Article

References (55)

1. Dorreen MS, Habeshaw JA, Stansfeld AG, Wrigley PF, Lister TA. Characteristics of Sternberg-Reed, and related cells in Hodgkin's disease: an immunohistological study. Br J Cancer 1984;49:465-76.
2. Gruss H-J, Pinto A, Duyster J, Poppema S, Herrmann F. Hodgkin's disease: a tumor with disturbed immunological pathways. Immunol Today 1997;18:156-63.
3. Coussens LM, Werb Z. Inflammatory cells and cancer: think different! J Exp Med 2001;193:F23-6.
4. Carlos TM, Harlan JM. Leukocyte-endothelial adhesion molecules. Blood 1994;84:2068-101.
5. Simmons D, Makgoba MW, Seed B. ICAM, an adhesion ligand of LFA-I, is homologous to the neural cell adhesion molecule NCAM. Nature 1988;331:624-7.
6. Marlin SD, Springer TA. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell 1987;51:813-9.
7. Ruco LP, Pomponi D, Pigott R, Gearing AJ, Baiocchini A, Baroni CD. Expression and cell distribution of the intercellular adhesion molecule, vascular cell adhesion molecule, endothelial leukocyte adhesion molecule, and endothelial cell adhesion molecule (CD31) in reactive human lymph nodes and in Hodgkin's disease. Am J Pathol 1992; 140:1337-44.
8. Banks RE, Gearing AJ, Hemingway IK, Norfolk DR, Perren TJ, Selby PJ. Circulating intercellular adhesion molecule-1 (ICAM-1), E-selectin and vascular cell adhesion molecule-1 (VCAM-1) in human malignancies. Br J Cancer 1993;68:122-4.
9. Pizzolo G, Vinante F, Nadali G, Ricetti MM, Morosato L, Marrocchella R, Vincenzi C, Semenzato G, Chilosi M. ICAM-1 tissue overexpression associated with increased serum levels of its soluble form in Hodgkin's disease. Br J Haematol 1993;84:161-2.
10. Christiansen I, Enblad G, Kalkner KM, Gidlof C, Glimelius B, Totterman TH. Soluble ICAM-1 in Hodgkin's disease: a promising independent predictive marker for survival. Leuk Lymphoma 1995;19: 243-51.
11. Gruss H-J, Dower SK. Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas. Blood 1995; 85:3378-404.
12. Falini B, Pileri S, Pizzolo G, Durkop H, Flenghi L, Stirpe F, Martelli MF, Stein H. CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy. Blood 1995;85:1-14.
13. Schwab U, Stein H, Gerdes J, Lemke H, Kirchner H, Schaadt M, Diehl V. Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin's disease and a subset of normal lymphoid cells. Nature 1982;299:65-7.
14. Nadali G, Tavecchia L, Zanolin E, Bonfante V, Viviani S, Camerini E, Musto P, Di Renzo N, Carotenuto M, Chilosi M, Krampera M, Pizzolo G. Serum level of the soluble form of the CD30 molecule identifies patients with Hodgkin's disease at high risk of unfavorable outcome. Blood 1998;91:3011-6.
15. Stein H, Mason DY, Gerdes J, O'Connor N, Wainscoat J, Pallesen G, Gatter K, Falini B, Delsol G, Lemke H, Schwarting R, Lennert K. The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 1985;66:848-58.
16. Pinto A, Aldinucci D, Gloghini A, Zagonel V, Degan M, Improta S, Juzbasic S, Todesco M, Perin V, Gattei V, Herrmann F, Gruss H-J, et al. Human eosinophils express functional CD30 ligand and stimulate proliferation of a Hodgkin's disease cell line. Blood 1996;88: 3299-305.
17. Younes A, Consoli U, Zhao S, Snell V, Thomas E, Gruss H-J, Cabanillas F, Andreeff M. CD30 ligand is expressed on resting normal and malignant human B lymphocytes. Br J Haematol 1996;93: 569-71.
18. Gruss H-J, Boiani N, Williams DE, Armitage RJ, Smith CA, Goodwin RG. Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines. Blood 1994;83:2045-56.
19. Masuda M, Ishida C, Arai Y, Okamura T, Ohsawa M, Shimakage M, Mizoguchi H. Dual action of CD30 antigen: anti-CD30 antibody induced apoptosis and interleukin-8 secretion in Ki-1 lymphoma cells. Int J Hematol 1998;67:257-65.
20. Leca G, Vita N, Maiza H, Fasseu M, Bensussan A. A monoclonal antibody to the Hodgkin's disease-associated antigen CD30 induces activation and long-term growth of human autoreactive γδ T cell clone. Cell Immunol 1994;156:230-9.
21. McDonald PP, Cassatella MA, Bald A, Maggi E, Romagnani S, Gruss H-J, Pizzolo G. CD30 ligation induces nuclear factor-κB activation in human T cell lines. Eur J Immunol 1995;25:2870-6.
22. Bowen MA, Lee RK, Miragliotta G, Nam SY, Podack ER. Structure and expression of murine CD30 and its role in cytokine production. J Immunol 1996;156:442-9.
23. Baker SJ, Reddy EP. Modulation of life and death by the TNF receptor superfamily. Oncogene 1998;17:3261-70.
24. Gedrich RW, Gilfillan MC, Duckett CS, Van Dongen JL, Thompson CB. CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins. J Biol Chem 1996;271:12852-8.
25. Lee SY, Lee SY, Kandala G, Liou M-L, Liou H-C, Choi Y. CD30/TNF receptor-associated factor interaction: NF-κB activation and binding specificity. Proc Natl Acad Sci USA 1996;93:9699-9703.
26. Aizawa S, Nakano H, Ishida T, Horie R, Nagai M, Ito K, Yagita H, Okumura K, Inoue J, Watanabe T. Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFκB activation. J Biol Chem 1997;272:2042-5.
27. Horie R, Aizawa S, Nagai M, Ito K, Higashihara M, Ishida T, Inoue J, Watanabe T. A novel domain in the CD30 cytoplasmic tail mediates NFκB activation. Int Immunol 1998;10:203-10.
28. Horie R, Watanabe T, Morishita Y, Ito K, Ishida T, Kanegae Y, Saito I, Higashihara M, Mori S, Kadin ME, Watanabe T. Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells. Oncogene 2002;21:2493-503.
29. Brockman JA, Scherer DC, McKinsey TA, Hall SM, Qi X, Lee WY, Ballard DW. Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation. Mol Cell Biol 1995;15:2809-18.
30. McKinsey TA, Brockman JA, Scherer DC, Al-Murrani SW, Green PL, Ballard DW. Inactivation of IκBβ by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-κB. Mol Cell Biol 1996;16:2083-90.
31. Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET Jr, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC. Human T-cell leukemia virus type 1 Tax induction of NF-κB involves activation of the IκB kinase α (IKKα) and IKKβ cellular kinases. Mol Cell Biol 1998;18:5157-65.
32. Voraberger G, Schafer R, Stratowa C. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Induction by cytokines and phorbol ester. J Immunol 1991; 147:2777-86.
33. Ledebur HC, Parks TP. Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-κB site and p65 homodimers. J Biol Chem 1995;270:933-43.
34. Gattei V, Degan M, Gloghini A, De Iuliis A, Improta S, Rossi FM, Aldinucci D, Perin V, Serraino D, Babare R, Zagonel V, Gruss H-J, et al. CD30 ligand is frequently expressed in human hematopoietic malignancies of myeloid and lymphoid origin. Blood 1997;89:2048-59.
35. Ansai T, Yamamoto E, Awano S, Yu W, Turner AJ, Takehara T. Effects of periodontopathic bacteria on the expression of endothelin-1 in gingival epithelial cells in adult periodontitis. Clin Sci 2002;103: 327S-31S.
36. Mori N, Fujii M, Ikeda S, Yamada Y, Tomonaga M, Ballard DW, Yamamoto N. Constitutive activation of NF-κB in primary adult T-cell leukemia cells. Blood 1999;93:2360-8.
37. Springer TA. Adhesion receptors of the immune system. Nature 1990; 346:425-34.
38. Nam S-Y, Cho K-S, Heo Y-M, Ha J-C, Kim Y-H, Keun YK, Han Hwang P, Kim H-M, Podack ER. Regulation of lymphocyte clustering by CD30-mediated ICAM-1 up-regulation. Cell Immunol 2002;219: 38-47.
39. Hou J, Baichwal V, Cao Z. Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1. Proc Natl Acad Sci USA 1994;91:11641-5.
40. Ghosh S, May MJ, Kopp EB. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 2000; 16:225-60.
41. Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu Rev Immunol 2000;18:621-63.
42. Zandi E, Karin M. Bridging the gap: composition, regulation, and physiological function of the IκB kinase complex. Mol Cell Biol 1999; 19:4547-51.
43. Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV. IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 1997;278:866-9.
44. Lee FS, Peters RT, Dang LC, Maniatis T. MEKK1 activates both IκB kinase α and IκB kinase β. Proc Natl Acad Sci USA 1998;95:9319-24.
45. Horie R, Higashihara M, Watanabe T. Hodgkin's lymphoma and CD30 signal transduction. Int J Hematol 2003;77:37-47.
46. Dougherty GJ, Hogg N. The role of monocyte lymphocyte function-associated antigen 1 (LFA-1) in accessory cell function. Eur J Immunol 1987;17:943-7.
47. Wang P, Vanky F, Li SL, Patarroyo M, Klein E. Functional characteristics of the intercellular adhesion molecule-1 (CD54) expressed on cytotoxic human blood lymphocytes. Cell Immunol 1990;131:366-80.
48. Bowen MA, Olsen KJ, Cheng L, Avila D, Podack ER. Functional effects of CD30 on a large granular lymphoma cell line, YT. Inhibition of cytotoxicity, regulation of CD28 and IL-2R, and induction of homotypic aggregation. J Immunol 1993;151:5896-906.
49. Hinz M, Lemke P, Anagnostopoulos I, Hacker C, Krappmann D, Mathas S, Dorken B, Zenke M, Stein H, Scheidereit C. Nuclear factor κB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity. J Exp Med 2002; 196:605-17.
50. Bargou RC, Leng C, Krappmann D, Emmerich F, Mapara MY. Bommert K, Royer HD, Scheidereit C, Dorken B. High-level nuclear NF-κB and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells. Blood 1996;87:4340-7.
51. Cabannes E, Khan G, Aillet F, Jarrett RF, Hay RT. Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IκBα. Oncogene 1999;18:3063-70.
52. Emmerich F, Meiser M, Hummel M, Demel G, Foss HD, Jundt F, Mathas S, Krappmann D, Scheidereit C, Stein H, Dorken B. Overexpression of I kappa B alpha without inhibition of NF-κB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells. Blood 1999;94:3129-34.
53. Krappmann D, Emmerich F, Kordes U, Scharschmidt E, Dorken B, Scheidereit C. Molecular mechanisms of constitutive NF-κB/Rel activation in Hodgkin/Reed-Sternberg cells. Oncogene 1999;18:943-53.
54. Gruss H-J, Pinto A, Gloghini A, Wehnes E, Wright B, Boiani N, Aldinucci D, Gattei V, Zagonel V, Smith CA, Kadin ME, von Schilling C, et al. CD30 ligand expression in nonmalignant and Hodgkin's disease-involved lymphoid tissues. Am J Pathol 1996;149:469-81.
55. Molin D, Fischer M, Xiang Z, Larsson U, Harvima I, Venge P, Nilsson K, Sundstrom C, Enblad G, Nilsson G. Mast cells express functional CD30 ligand and are the predominant CD30L-positive cells in Hodgkin's disease. Br J Haematol 2001;114:616-23.