MCL0042: A nonpeptidic MC4 receptor antagonist and serotonin reuptake inhibitor with anxiolytic- and antidepressant-like activity

Pharmacology Biochemistry and Behavior

Volumn 82, Issue 4, 2005, Pages 621-626

  Chaki, Shigeyuki ^a   Oshida, Yuichi ^a   Ogawa, Shin Ichi ^a   Funakoshi, Takeo ^a   Shimazaki, Toshiharu ^a   Okubo, Taketoshi ^a   Nakazato, Atsuro ^a   Okuyama, Shigeru ^a  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Antidepressant; Anxiolytic; MC4 receptor; MCL0042; Serotonin transporter

Indexed keywords

1 [2 (4 FLUOROPHENYL) 2 (METHYLPIPERAZIN 1 YL)ETHYL] 4 [4 (1 NAPHTHYL)BUTYL]PIPERAZINE; ANTIDEPRESSANT AGENT; MCL 0042; MELANOCORTIN 4 RECEPTOR; PIPERAZINE DERIVATIVE; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DRINKING; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; FORCED SWIMMING TEST; HYPERACTIVITY; MALE; MAZE TEST; NONHUMAN; OLFACTORY BULBECTOMY; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SEROTONIN UPTAKE; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CERCOPITHECUS AETHIOPS; COS CELLS; MALE; MOTOR ACTIVITY; NAPHTHALENES; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MELANOCORTIN, TYPE 4; SEROTONIN UPTAKE INHIBITORS;

ANIMALIA;

EID: 31844449063     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.11.001     Document Type: Article

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