Subcellular localization and regulation of type-1C and type-5 phosphodiesterases

Biochemical and Biophysical Research Communications

Volumn 341, Issue 3, 2006, Pages 837-846

  Dolci, Susanna ^a   Belmonte, Alessia ^a   Santone, Rocco ^c   Giorgi, Mauro ^c   Pellegrini, Manuela ^a   Carosa, Eleonora ^d   Piccione, Emilio ^a   Lenzi, Andrea ^b   Jannini, Emmanuele A ^d  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

Phosphodiesterases; Signal transduction; Sildenafil; Uterus

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLIC GMP; PHOSPHODIESTERASE I; PHOSPHODIESTERASE V; SILDENAFIL;

ARTICLE; CELLULAR DISTRIBUTION; CENTROSOME; DRUG INHIBITION; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MITOSIS RATE; MYOMETRIUM; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; UPREGULATION;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ADULT; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; CYCLIC GMP; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MYOMETRIUM; PHOSPHORIC DIESTER HYDROLASES; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; UP-REGULATION;

ANIMALIA;

EID: 31744449519     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.035     Document Type: Article

References (41)

1. G.K. Owens Regulation of differentiation of vascular smooth muscle cells Physiol. Rev. 75 1995 487 517
2. J.A. Beavo Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms Physiol. Rev. 75 1995 725 748
3. S.H. Soderling, and J.A. Beavo Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions Curr. Opin. Cell. Biol. 12 2001 174 179
4. L. Fawcett, R. Baxendale, P. Stacey, C. McGrouther, I. Harrow, S. Soderling, J. Hetman, J.A. Beavo, and S.C. Phillips Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A Proc. Natl. Acad. Sci. USA 97 2000 3702 3707
5. S.D. Rybalkin, K.E. Bornfeld, W.K. Sonnenburg, I.G. Rybalkina, K.S. Kwak, K. Hanson, E.G. Krebs, and J.A. Beavo Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype J. Clin. Invest. 100 1997 2611 2621
6. I. Goldstein, T.F. Lue, H. Padma-Nathan, R.C. Rosen, W.D. Steers, and P.A. Wicker Oral sildenafil in the treatment of erectile dysfunction N. Engl. J. Med. 338 1998 1397 1404
7. J.R. Berman, L.A. Berman, S.M. Toler, J. Gill, and S. Haughies Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorders: a double-blind, placebo controlled study J. Urol. 170 2003 2333 2338
8. G. Sher, and J.D. Fish Vaginal sildenafil (Viagra): a preliminary report of a new method to improve uterine artery blood flow and endometrial development in patients undergoing IVF Hum. Reprod. 15 2000 806 809
9. A.M. Agha, and R.A. Taha Sildenafil inhibits agonist-evoked rat uterine contractility: influence of guanylyl cyclase inhibition Eur. J. Pharmacol. 428 2001 343 348
10. C.S. Buhimschi, R.E. Garfield, C.P. Weiner, and I.A. Buhimschi The presence and function of phosphodiesterase type 5 in the rat myometrium Am. J. Obstet. Gyncol. 190 2004 268 274
11. M. Boolell, M.J. Allen, S.A. Ballard, S. Gepi-Attee, G.J. Muirhead, A.M. Naylor, I.H. Osterloh, and C. Gingell Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction Int. J. Impot. Res. 8 1996 47 52
12. D. Giordano, M.E. De Stefano, G. Citro, A. Modica, and M. Giorgi Expression of cGMP-binding c-GMP-phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain Biochem. Biophys. Acta 1539 2001 16 27
13. G. d'Amati, C.R. di Gioia, M. Bologna, D. Giordano, M. Giorgi, S. Dolci, and E.A. Jannini Type 5 phosphodiesterase expression in the human vagina Urology 60 2002 191 195
14. A. Morelli, S. Filippi, R. Mancina, M. Luconi, L. Vignozzi, M. Marini, C. Orlando, G.B. Vannelli, A. Aversa, A. Natali, G. Forti, M. Giorgi, E.A. Jannini, F. Ledda, and M. Maggi Androgens regulate phosphodiesterase type 5 expression and functional activity in corpora cavernosa Endocrinology 145 2004 2253 2263
15. K.A. Taskén, P. Collas, W.A. Kemmner, O. Witczak, M. Conti, and K. Taskén Phosphodiesterase 4D and protein kinase A Type II constitute a signaling unit in the centrosomal area J. Biol. Chem. 276 2001 21999 22002
16. K. Loughney, T.R. Hill, V.A. Florio, L. Uher, G.J. Rosman, S.L. Wolda, B.A. Jones, M.L. Howard, L.M. McAllister-Lucas, W.K. Sonnenburg, S.H. Francis, J.D. Corbin, J.A. Beavo, and K. Ferguson Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding cGMP-specific 3′,5′-cyclic nucleotide phosphodiesterase Gene 216 1998 139 147
17. J.F. Krall, M. Fittingoff, and J. Rajfer Characterization of cyclic nucleotide and inositol 1,4,5-trisphosphate-sensitive calcium-exchange activity of smooth muscle cells cultured from the human corpora cavernosa Biol. Reprod. 39 1988 913 922
18. P. Stacey, S. Rulten, A. Dapling, and S.C. Phillips Molecular cloning and expression of human cGMP-binding cGMP-specific phosphodiesterase (PDE5) Biochem. Biophys. Res. Commun. 247 1998 249 254
19. W.J. Thomson, and M.M. Appleman Multiple cyclic nucleotide phosphodiesterase activities from rat brain Biochemistry 10 1971 311 316
20. S.D. Rybalkin, I.G. Rybalkina, R. Feil, F. Hofman, and J.A. Beavo Regulation of cGMP-specific phosphodiesterase (PDE5) phosphorylation in smooth muscle cells J. Biol. Chem. 277 2002 3310 3317
21. E. Bailly, M. Doree, P. Nurse, and M. Bornens p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase EMBO J. 8 1989 3985 3995
22. T. Stearns, and M. Kirschner In vitro reconstitution of centrosome assembly and function: the central role of gamma-tubulin Cell 76 1994 623 637
23. I. Boulven, B. Palmier, P. Robin, M. Vacher, S. Harbon, and D. Leiber Platelet-derived growth factor stimulates phospholipase C-gamma 1, extracellular signal-regulated kinase, and arachidonic acid release in rat myometrial cells: contribution to cyclic 3′,5′-adenosine monophosphate production and effect on cell proliferation Biol. Reprod. 65 2001 496 506
24. S.D. Rybalkin, C. Yan, K.E. Bornfeldt, and J.A. Beavo Cyclic GMP phosphodiesterases and regulation of smooth muscle function Circ. Res. 93 2003 280 291
25. S. Fukumoto, H. Koyama, M. Hosoi, K. Yamakawa, S. Tanaka, H. Morii, and Y. Nishizawa Distinct role of cAMP and cGMP in cell cycle control of vascular smooth muscle cells: cGMP delays cell cycle transition to through suppression of cyclin D1 and cyclin-dependent kinase 4 activation Circ. Res. 85 1999 985 991
26. T. Sterns Centrosome duplication, a centriolar pas de deux Cell 105 2001 417 420
27. A.M. Tassin, and M. Bornens Centrosome structure and microtubule nucleation in animal cells Biol. Cell 91 1999 343 354
28. D. Diviani, and J.D. Scott AKAP signaling complexes at the cytoskeleton J. Cell Sci. 114 2001 1431 1437
29. M.J. Leroy, C. Lugnier, J. Merezak, G. Tanguy, S. Olivier, A. Le Bec, and F. Ferrè Isolation and characterization of the rolipram-sensitive AMP-specific phosphodiesterase (type IV PDE) in human term myometrium Cell. Signal. 6 1994 405 412
30. J.H. Chamley-Campbell, G.R. Campbell, and R. Ross The smooth muscle cell in culture Physiol. Rev. 59 1979 1 6
31. U.C. Garg, and A. Hassid Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells J. Clin. Invest. 83 1989 1774 1777
32. J.W. Assender, K.M. Southgate, M.B. Hallett, and A.C. Newby Inhibition of proliferation, but not of Ca2 mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells Biochem. J. 288 1992 527 532
33. H. Koyama, K.E. Bornfeldt, S. Fukumoto, and Y. Nishizawa Molecular pathways of cyclic nucleotide-induced inhibition of arterial smooth muscle cell proliferation J. Cell. Physiol. 186 2001 1 10
34. M.T. Osinski, B.H. Rauch, and K. Schror Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A Mol. Pharmacol. 59 2001 1044 1050
35. X.L. Pan, E. Arauz, J.J. Krzanowski, D.F. Fitzpatrick, and J.B. Polson Sinergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDSE IV to attenuate proliferation of rat vascular smooth muscle cells Biochem. Pharmacol. 48 1994 827 835
36. J.E. Souness, G.A. Hassall, and D.P. Parrott Inhibition of pig aortic smooth muscle cell DNA synthesis by selective type III and type IV cyclic AMP phosphodiesterase inhibitors Biochem. Pharmacol. 44 1992 857 866
37. A. Hassid, H. Arabshahi, T. Bourcier, G.S. Dhaunsi, and C. Matthews Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells Am. J. Physiol. 267 1994 H1040 H1048
38. G.S. Dhaunsi, and A. Hassid Atrial and C-type natriuretic peptides amplify growth factor activity in primary aortic smooth muscle cells Cardiovasc. Res. 3 1996 37 47
39. G.S. Dhaunsi, C. Matthews, K. Kaur, and A. Hassid NO increases protein tyrosine phosphatase activity in smooth muscle cells: relationship to antimitogenesis Am. J. Physiol. 272 1997 H1342 H1349
40. J.W. Downing, R. Ramasubramanian, R..F. Johnson, B.H. Minzter, R.L. Paschall, H.W. Sundell, B. Engelhardt, and R. Lewis Hypothesis: selective phosphodiesterase-5 inhibition improves outcome in preeclampsia Med. Hypotheses 63 2004 1057 1064
41. A. Belmonte, C. Ticconi, S. Dolci, M. Giorgi, A. Zicari, A. Lenzi, E.A. Jannini, and E. Piccione Regulation of phophodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin J. Soc. Gynecol. Invest. 12 2005 570 577