Tilia cordata Mill. Extracts and scopoletin (isolated compound): Differential cell growth effects on lymphocytes

Phytotherapy Research

Volumn 20, Issue 1, 2006, Pages 34-40

  Barreiro Arcos, Maria Laura ^b   Cremaschi, Graciela ^b   Werner, Silvia ^b   Coussio, Jorge ^a   Ferraro, Graciela ^a   Anesini, Claudia ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b Centre de Estudios Farmacologicos y Botanicos   (Argentina)

Author keywords

Antiproliferative activity; Apoptosis; Cell viability; Lymphoma cells; Normal lymphocytes; Scopoletin; Tilia

Indexed keywords

ALCOHOL; ANTINEOPLASTIC AGENT; COUMARIN DERIVATIVE; DICHLOROMETHANE; MITOGENIC AGENT; PLANT EXTRACT; SCOPOLETIN; TILIA CORDATA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AQUEOUS SOLUTION; ARTICLE; CELL GROWTH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG INFUSION; FLOWER; LYMPHOCYTE PROLIFERATION; LYMPHOMA CELL; MOUSE; NONHUMAN; T LYMPHOCYTE; TILIA CORDATA; TILIACEAE; TRADITIONAL MEDICINE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOWERS; LYMPHOCYTES; MALE; METHYLENE CHLORIDE; MICE; MICE, INBRED C3H; NECROSIS; PHYTOTHERAPY; PLANT EXTRACTS; SCOPOLETIN; SOLVENTS; TILIA;

ANIMALIA; MALVACEAE; TILIA; TILIA CORDATA;

EID: 31644438506     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.1798     Document Type: Article

References (26)

1. 50. J Pharmacol Toxicol 41: 55-58.
2. Anesini C, Genaro A, Cremaschi G, Sterin Borda L, Cazaux C, Borda E. 1996. Immunomodulatory activity of Larrea divaricate Cav. Fitoterapia 67: 329-333.
3. Anesini C, Werner S, Borda E. 1999. Effect of Tilia cordata Mill, flowers on lymphocyte proliferation: participation of peripheral type benzodiazepine binding sites. Fitoterapia 1999; 70: 361-367.
4. Araki T, Tamamoto A, Tamada M. 1987. Accurate determination of DNA content in single cell nuclei stained with Hoechst 33258 fluorochrome at high salt concentration. Histochemistry 87: 331-338.
5. Benencia F, Courreges M, Coulombie F. 2000. 'In vivo' and 'in vitro' immunomodulatory activities of Trichilia glabra aqueous extract leaf. J Ethnopharmacol 69: 199-205.
6. Cremaschi G, Fisher P, Boege F. 1991. β Adrenoceptor distribution in murine lymphoid cell line. Immunopharmacology 22: 195-206.
7. Dunnett CW. 1964. New tables of multiples comparisons with control. Biometrics 20: 482-491.
8. Font Quer R. 1976. Plantas Medicinales: el Dioscórides Renovado. Font Quer R (ed.). Editorial Labor: Madrid, 408-410.
9. Fujioka T, Furumi K, Fujii H et al. 1999. Antiproliferative constituents from Umbeliferae plants. V. A new furanocoumarin and falcarindiol furanocoumarin ethers from root of Angelica japonica. Chem Pharm Bull 47: 96-100.
10. Harbone JB. 1973. Methods of Plant Analysis, 2nd edn. Chapman and Hall: London, 1-36.
11. Hu H, Ahn NS, Yang X, Lee YS, Kang KS. 2002. Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell. Int J Cancer 102: 250-253.
12. Knowles LM, Zigrossi DA, Tauber RA, Hightower C, Milner JA. 2000. Flavonoids suppress androgen-independent human prostate tumor proliferation. Nutr Cancer 38: 116-122.
13. Lee SM, Li ML, Tse YC, et al. 2002. Paeoniae radix a Chinese herbal extract inhibits hepatoma cells growth by inducing apoptosis in a P53 independent pathway. Life Sci 712: 2267-2277.
14. Liu XL, Sun JY, Li HY, Zhang L, Qian BC. 2000. Extraction and isolation of active component for inhibiting PCS cell proliferation in vitro from fruit of Lycium barbatum L. Zhonguo Zhong Yao Za Zhi 25: 481-483.
15. Liu XL, Zhang L, Fu XL, Chen K, Qian BC. 2002. Effect of scopoletin on PC(3) cell proliferation and apoptosis. Acta Pharmacol Sin 22: 929-933.
16. Mutoh M, Takahashi M, Fukuda K, et al. 2000. Suppression of cyclooxygenase-2 promoter-dependent transcriptional activity in colon cancer cells by chemopreventive agents with a resorcin-type structure. Carcinogenesis 21: 959-963.
17. Olayiwola Akerele. 1993. Medicina tradicional. Foro Mund Salud 14: 390-395.
18. Ratera E, Ratera M. 1980. Plantas de la Flora Argentina Empleadas en Medicina Popular. Hemisferio Sur: Buenos Aires, 1-105.
19. Richter M, Ebermann R, Marian B. 1999. Quercetin-induced apoptosis in colorectal cells: possible role of EGF receptor signaling. Nutr Cancer 34: 88-99.
20. Russso A, Acquaviva R, Campisi A et al. 2000. Bioflavonoids as antiradicals, antioxidant and DNA cleavage protectors. Cell Biol Toxicol 16: 91-98.
21. Syu WJ, Don MJ, Lee GH, Sun CM. 2001. Cytotoxic and novel compounds from Solanum indicum. J Nat Prod 64: 1232-1233.
22. Thomson A. (ed.). (1987). Healing Plants (A Modern Herbal). Mc Graw Hill: London, 105-113.
23. Toker G, Asian M, Yesilada E, Memisoglu M, Ito S. 2001. Comparative evaluation of the flavonoids content in officinal Tiliae flos and Turkish lime species for quality assessment. J Pharm Biomed Anal 26: 111-121.
24. Toursarkissian M. 1980. Plantas Medicinales de la Argentina: Sus Nombres Botánicos, Vulgares, Usos y Distribución Geográfica. Hemisferio Sur: Buenos Aires, 1-139.
25. Viola H, Wolfman C, Levi de Stein M et al. 1994. Isolation of pharmacologically active benzodiazepine receptors ligands from Tilia tomentosa (Tiliaceae). J Ethnopharmacol 44: 47-53.
26. Wang IK, Lin-Shiau SY, Lin JK. 1999. Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. Eur J Cancer 35: 1517-1525.