In vivo and in vitro immunomodulatory activities of Trichilia glabra aqueous leaf extracts

Journal of Ethnopharmacology

Volumn 69, Issue 3, 2000, Pages 199-205

  Benencia, Fabián ^a   Courrèges, María Cecilia ^a   Coulombié, Félix Carlos ^a  

^a Laboratorio de Virologia Ciudad Autonoma de Buenos Aires   (Argentina)

Author keywords

Antibodies; Delayed type hypersensitivity response; Immunomodulatory effect; Leaf extract; Mouse; Trichilia glabra

Indexed keywords

ANTIBODY; PLANT EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; EXTRACTION; FEMALE; HYPERSENSITIVITY REACTION; IMMUNE SYSTEM; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; MEDICINAL PLANT; MOUSE; NONHUMAN; PLANT LEAF; T LYMPHOCYTE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODY FORMATION; CELL DIVISION; FEMALE; HYPERSENSITIVITY, DELAYED; LYMPHOCYTES; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL;

EID: 0342546052     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(99)00010-0     Document Type: Article

References (17)

1. Andrei G.M., Coulombié F.C., Courrèges M.C., de Torres R.A., Coto C.E. Melicine, an antiviral compound from Melia azedarach L., inhibits interferon production. Journal of Interferon Research. 10:1990;469-475.
2. Benencia F.and, Coulombié F.C. Immunomodulatory activities of Trichilia glabra leaf aqueous extracts. Phytotherapy Research. 12/3:1998;167-171.
3. Benencia F., Courrèges M.C., Massouh E.J., Coulombié F.C. Effect of Melia azedarach L. leaf extracts on human complement and polymorphonuclear leukocytes. Journal of Ethnopharmacology. 41:1994;53-57.
4. Benencia F., Courrèges M.C., Nores M.M., Coulombié F.C. Immunomodulatory activities of Cedrela tubiflora leaf aqueous extracts. Journal of Ethnopharmacology. 49:1995;133-139.
5. Benencia F., Courrèges M.C., Coulombié F.C. In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement. Phytotherapy Research. 10:1996;37-41.
6. Bhakuni D.S., Dhar M.L., Dhar M., Dhawan B.W., Mehratra B.N. Screening of plants for biological activity. Part II. Indian Journal of Experimental Biology. 7:1969;250-262.
7. Bray D.H., Warhurst D.C., Connolly J.D., O'Neill M.J., Phillipson J.D. Plants as sources of antimalarial drugs. Part 7. Activity of some species of Meliaceae plants and their constituent limonoids. Phytotherapy Research. 4:1990;29-34.
8. Coulombié F.C., Andrei G.M., Laguens R.P., de Torres R.A., Coto C.E. Partially purified leaf extracts of Melia azedarach L. inhibit Tacaribe virus growth in neonatal mice. Phytotherapy Research. 6:1992;15-19.
9. Courrèges M.C., Benencia F., Coto C.E., Massouh E.J., Coulombié F.C. In vitro antiphagocytic effect of Melia azedarach leaf extracts on mouse peritoneal exudate cells. Journal of Ethnopharmacology. 43:1994;135-140.
10. Courrèges M.C., Benencia F., Coulombié F.C., Coto C.E. Immunomodulatory activity of Melia azedarach L. Aqueous leaf extracts on murine lymphocytes. Phytomedicine. 5(1):1998;47-53.
11. Ford W.L., Burr W., Simonsen M. A lymph node weight assay fr the Graft vs. Host activity of rat lymphoid cells. Transplantation. 10:1970;258-263.
12. Fujiwara T., Takeda T., Ogihara Y., Shimizu M., Nomura T., Tomita T. Studies of the structure of polysaccharides from the bark of Melia azadirachta. Chemical and Pharmaceutical Bulletin. 30:1982;4025-4030.
13. Hudson L., Hay P. Chapter 5: Antibody interaction with antigen. Thomas A. Practical Immunology. 1980;131 Blackwell, Edinburgh.
14. Labadie R.P., Van der Nat J.M., Simons J.M., Kroes B.H., Kosasi S., Van der Berg A.J.J., t'Hart L.A., Van der Sluis S., Abeysekera A., Bamunuarachchi A., de Silva K.T.D. An ethnopharmacognostic approach to the search of immunomodulators of plant origin. Planta Medica. 55:1989;339-348.
15. Nores M.M., Courrèges M.C., Benencia F., Coulombie F.C. Immunomodulatory activity of Cedrela lilloi and Trichilia elegans aqueous leaf extracts. Journal of Ethnopharmacology. 55:1997;99-106.
16. Patel N.G. Indians traditional medicine: ayurveda. Steiner R.P. Folk Medicine: the Art and Science. 1986;57 American Chemical Society, Washington DC.
17. Van der Nat J.M., Klerx J.P.A.M., Van Dijk H., de Silva K.T.D., Labadie R.P. Immunomodulatory activity of an aqueous extract of Azadirachta indica stem bark. Journal of Ethnopharmacology. 19:1987;125-131.