Total synthesis of UCS1025A

Journal of the American Chemical Society

Volumn 128, Issue 2, 2006, Pages 426-427

  Lambert, Tristan H ^a   Danishefsky, Samuel J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PYRROLIZIDINE DERIVATIVE; TELOMERASE; TELOMERASE INHIBITOR; UC 1025A; UCS 1025A; UNCLASSIFIED DRUG;

ARTICLE; CANCER; CELL DIVISION; CELL IMMORTALIZATION; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; EPIMERIZATION; REACTION ANALYSIS; REFORMATSKY REACTION; SAPONIFICATION; STRUCTURE ANALYSIS; TELOMERE;

ACREMONIUM; ANTINEOPLASTIC AGENTS; ENZYME INHIBITORS; PYRROLIZIDINE ALKALOIDS; TELOMERASE;

EID: 31544474367     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0574567     Document Type: Article

References (11)

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7. For an encouraging precedent, see: Dvornikovs, V.; Hoye, T. R. Abstr. Papers American Chemical Society Series 229, 2005, 665-ORGN. Professor Hoye has kindly informed us of his substantial progress toward this target using a very different attachment strategy.
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11. The stereochemistry of the hydroxy group of 18 has not yet been determined.