Dendritic cells regulate T-cell deattachment through the integrin-interacting protein CYTIP

Blood

Volumn 107, Issue 3, 2006, Pages 1003-1009

  Hofer, Susanne ^b   Pfeil, Karina ^b   Niederegger, Harald ^b   Ebner, Susanne ^b   Van Nguyen, Anh ^b   Kremmer, Elisabeth ^b   Auffinger, Margit ^b   Neyer, Susanne ^b   Fürhapter, Christina ^b   Heufler, Christine ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CYTOHESIN INTERACTING PROTEIN; FIBRONECTIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL INTERACTION; CELL MATURATION; CELL SPECIFICITY; COCULTURE; CONTROLLED STUDY; DENDRITIC CELL; GENE CONTROL; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; T LYMPHOCYTE;

EID: 31544448830     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-01-0425     Document Type: Article

References (26)

1. Dustin ML, Chan AC. Signaling takes shape in the immune system. Cell. 2000;103:283-294.
2. Bajenoff M, Granjeaud S, Guerder S. The strategy of T cell antigen-presenting cell encounter in antigen-draining lymph nodes revealed by imaging of initial T cell activation. J Exp Med. 2003; 198:715-724.
3. Creusot RJ, Mitchison NA. How DCs control cross-regulation between lymphocytes. Trends Immunol. 2004;25:126-131.
4. Wang JH, Eck MJ. Assembling atomic resolution views of the immunological synapse. Curr Opin Immunol. 2003;15:286-293.
5. Boehm T, Hofer S, Winklehner P, et al. Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration. EMBO J. 2003;22:1014-1024.
6. Romani N, Reider D, Heuer M, et al. Generation of mature dendritic cells from human blood: an improved method with special regard to clinical applicability. J Immunol Methods. 1996;196:137-151.
7. Ebner S, Neyer S, Hofer S, et al. Generation of large numbers of human dendritic cells from whole blood passaged through leukocyte removal filters: an alternative to standard buffy coats. J Immunol Methods. 2001;252:93-104.
8. Jonuleit H, Kühn U, Müller G, et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur J Immunol. 1997;27:3135-3142.
9. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor α,2: functional analysis. Blood. 1997;90:1458-1470.
10. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNFα. J Exp Med. 1996;184:695-706.
11. Lenz A, Heine M, Schuler G, Romani N. Human and murine dermis contain dendritic cells. Isolation by means of a novel method and phenotypical and functional characterization. J Clin Invest. 1993;92:2587-2596.
12. Pope M, Betjes MGH, Hirmand H, Hoffman L, Steinman RM. Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T-cell conjugates. J Invest Dermatol. 1995;104:11-17.
13. Romani N, Bhardwaj N, Pope M, et al. Dendritic cells. In: Herzenberg LA, Weir DM, Herzenberg L, Blackwell C, eds. Weir's Handbook of Experimental Immunology. Oxford, United Kingdom: Blackwell Science; 1997:156.1-156.14.
14. Cornelius LA, Sepp N, Li L-J, et al. Selective upregulation of intercellular adhesion molecule (ICAM-1) by ultraviolet B in human dermal microvascular endothelial cells. J Invest Dermatol. 1994;103:23-28.
15. + progenitors to resting human dermal microvascular endothelial cells is down-regulated upon maturation and partially depends on CD11a-CD18, CD11b-CD18 and CD36. Eur J Immunol. 2002; 32:3638-3650.
16. Johansson S, Svineng G, Wennerberg K, Armulik A, Lohikangas L. Fibronectin-integrin interactions. Front Biosci. 1997;2:d126-d146.
17. Geiger C, Nagel W, Boehm T, et al. Cytohesin-1 regulates beta-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1. EMBO J. 2000;19:2525-2536.
18. Kolanus W, Nagel W, Schiller B, et al. Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule. Cell. 1996;86:233-242.
19. Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A. 2004;101:998-1003.
20. Bousso P, Robey E. Dynamics of CD8(+) T cell priming by dendritic cells in intact lymph nodes. Nat Immunol. 2003;4:579-585.
21. Mempel TR, Henrickson SE, Von Andrian UH. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature. 2004;427: 154-159.
22. Lee KH, Holdorf AD, Dustin ML, et al. T cell receptor signaling precedes immunological synapse formation. Science. 2002;295:1539-1542.
23. Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A. 2004;101:998-1003.
24. Catron DM, Itano AA, Pape KA, Mueller DL, Jenkins MK. Visualizing the first 50 hr of the primary immune response to a soluble antigen. Immunity. 2004;21:341-347.
25. Itano AA, McSorley SJ, Reinhardt RL, et al. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity. 2003;19:47-57.
26. Itano AA, Jenkins MK. Antigen presentation to naive CD4 T cells in the lymph node. Nat Immunol. 2003;4:733-739.